52 items (Pelodiscus sinensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AP2A2	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (946 aa)
	AMN	Amnion associated transmembrane protein. (481 aa)
	SYT7	Synaptotagmin 7. (674 aa)
	RAB20	RAB20, member RAS oncogene family. (234 aa)
	RAB23	RAB23, member RAS oncogene family. (237 aa)
	RAB38	RAB38, member RAS oncogene family. (212 aa)
	APPL2	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (643 aa)
	INPP5F	Inositol polyphosphate-5-phosphatase F. (1101 aa)
	PIP4P1	Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (109 aa)
	RAB35	Uncharacterized protein. (193 aa)
	RAB9A	RAB9A, member RAS oncogene family. (201 aa)
	TLR2	TIR domain-containing protein; Belongs to the Toll-like receptor family. (783 aa)
	LOC102457570	TIR domain-containing protein; Belongs to the Toll-like receptor family. (783 aa)
	SLC18A3	Solute carrier family 18 member A3. (509 aa)
	K7F181_PELSI	MACPF domain-containing protein. (335 aa)
	SCARB2	Scavenger receptor class B member 2; Belongs to the CD36 family. (421 aa)
	K7FRF1_PELSI	Uncharacterized protein. (141 aa)
	RAB31	RAB31, member RAS oncogene family. (195 aa)
	SYT11	Synaptotagmin 11. (373 aa)
	MPEG1	Macrophage expressed 1. (700 aa)
	RABEP1	Rabaptin, RAB GTPase binding effector protein 1. (860 aa)
	AP2S1	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (122 aa)
	RAB14	RAB14, member RAS oncogene family. (215 aa)
	RIN3	Ras and Rab interactor 3. (973 aa)
	VAMP4	Vesicle associated membrane protein 4. (141 aa)
	LOC102463148	Uncharacterized protein. (178 aa)
	EMILIN2	Elastin microfibril interfacer 2. (1103 aa)
	CORO1B	Coronin; Belongs to the WD repeat coronin family. (481 aa)
	PIKFYVE	Phosphoinositide kinase, FYVE-type zinc finger containing. (1498 aa)
	K7FBX3_PELSI	Uncharacterized protein. (98 aa)
	RAB9B	RAB9B, member RAS oncogene family. (201 aa)
	PIP4P2	Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (222 aa)
	LMBRD1	LMBR1 domain containing 1. (540 aa)
	CORO1C	Coronin; Belongs to the WD repeat coronin family. (475 aa)
	RAB7B	RAB7B, member RAS oncogene family. (200 aa)
	APPL1	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (708 aa)
	OCRL	OCRL inositol polyphosphate-5-phosphatase. (716 aa)
	INPP5B	Inositol polyphosphate-5-phosphatase B. (862 aa)
	K7EXC9_PELSI	Uncharacterized protein. (448 aa)
	LOC102456214	Uncharacterized protein. (425 aa)
	TLR7	Toll like receptor 7; Belongs to the Toll-like receptor family. (1050 aa)
	CSF3R	Colony stimulating factor 3 receptor. (850 aa)
	RAB22A	RAB22A, member RAS oncogene family. (194 aa)
	TLR8	TIR domain-containing protein; Belongs to the Toll-like receptor family. (1037 aa)
	ANXA3	Annexin. (323 aa)
	RAB39A	RAB39A, member RAS oncogene family. (213 aa)
	SYK	Tyrosine-protein kinase. (445 aa)
	TLR6	Toll-like receptor. (653 aa)
	K7G218_PELSI	TIR domain-containing protein; Belongs to the Toll-like receptor family. (1043 aa)
	LAMP1	Lysosomal associated membrane protein 1. (397 aa)
	RAB32	RAB32, member RAS oncogene family. (218 aa)
	LYST	Lysosomal trafficking regulator. (3784 aa)

Your Current Organism:

Pelodiscus sinensis

NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AP2A2	AP2S1	ENSPSIP00000016265	ENSPSIP00000007963	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.998
AP2A2	SCARB2	ENSPSIP00000016265	ENSPSIP00000010778	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	Scavenger receptor class B member 2; Belongs to the CD36 family.	0.539
AP2A2	SLC18A3	ENSPSIP00000016265	ENSPSIP00000000541	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	Solute carrier family 18 member A3.	0.542
AP2A2	SYT11	ENSPSIP00000016265	ENSPSIP00000008555	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	Synaptotagmin 11.	0.439
AP2A2	VAMP4	ENSPSIP00000016265	ENSPSIP00000007340	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	Vesicle associated membrane protein 4.	0.542
AP2S1	AP2A2	ENSPSIP00000007963	ENSPSIP00000016265	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.998
AP2S1	APPL1	ENSPSIP00000007963	ENSPSIP00000007726	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.	0.439
AP2S1	APPL2	ENSPSIP00000007963	ENSPSIP00000018146	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.	0.439
AP2S1	VAMP4	ENSPSIP00000007963	ENSPSIP00000007340	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Vesicle associated membrane protein 4.	0.609
APPL1	AP2S1	ENSPSIP00000007726	ENSPSIP00000007963	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.439
APPL1	APPL2	ENSPSIP00000007726	ENSPSIP00000018146	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.	0.995
APPL1	INPP5B	ENSPSIP00000007726	ENSPSIP00000005544	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.	Inositol polyphosphate-5-phosphatase B.	0.563
APPL1	OCRL	ENSPSIP00000007726	ENSPSIP00000004597	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.	OCRL inositol polyphosphate-5-phosphatase.	0.640
APPL1	RAB20	ENSPSIP00000007726	ENSPSIP00000017255	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.	RAB20, member RAS oncogene family.	0.870
APPL1	RAB22A	ENSPSIP00000007726	ENSPSIP00000010974	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.	RAB22A, member RAS oncogene family.	0.870
APPL1	RAB31	ENSPSIP00000007726	ENSPSIP00000010047	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.	RAB31, member RAS oncogene family.	0.870
APPL2	AP2S1	ENSPSIP00000018146	ENSPSIP00000007963	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.439
APPL2	APPL1	ENSPSIP00000018146	ENSPSIP00000007726	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.	0.995
APPL2	RAB20	ENSPSIP00000018146	ENSPSIP00000017255	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.	RAB20, member RAS oncogene family.	0.870
APPL2	RAB22A	ENSPSIP00000018146	ENSPSIP00000010974	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.	RAB22A, member RAS oncogene family.	0.870