(87 nodes) Dendrite network (Pelodiscus sinensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APOD	Apolipoprotein D; Belongs to the calycin superfamily. Lipocalin family. (188 aa)
	CRIPT	CXXC repeat containing interactor of PDZ3 domain. (101 aa)
	SST	Somatostatin. (116 aa)
	NOS2	Nitric oxide synthase; Produces nitric oxide (NO). (1092 aa)
	RGS12	Regulator of G protein signaling 12. (1422 aa)
	DRD5	Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family. (465 aa)
	NSG1	Neuronal vesicle trafficking associated 1. (185 aa)
	PPP1R9B	Protein phosphatase 1 regulatory subunit 9B. (731 aa)
	ATP6AP2	ATPase H+ transporting accessory protein 2. (343 aa)
	IL1RAPL1	Interleukin 1 receptor accessory protein like 1. (669 aa)
	LAMP5	Lysosomal associated membrane protein family member 5. (222 aa)
	DHX36	DEAH-box helicase 36. (908 aa)
	K7G225_PELSI	PH domain-containing protein. (507 aa)
	CRHBP	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (322 aa)
	CADM1	Cell adhesion molecule 1. (404 aa)
	ARHGAP42	Rho GTPase activating protein 42. (820 aa)
	LZTS1	Leucine zipper tumor suppressor 1. (617 aa)
	ADCY3	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1125 aa)
	PVALB	Parvalbumin; Belongs to the parvalbumin family. (137 aa)
	LOC102463966	Uncharacterized protein. (1286 aa)
	MME	Membrane metalloendopeptidase. (750 aa)
	MAP2	Microtubule-associated protein. (1868 aa)
	INPP5A	Inositol polyphosphate-5-phosphatase A. (388 aa)
	ARFGEF2	ADP ribosylation factor guanine nucleotide exchange factor 2. (1493 aa)
	SYNPO	Synaptopodin. (739 aa)
	NCDN	Neurochondrin. (728 aa)
	ALS2	Alsin Rho guanine nucleotide exchange factor ALS2. (1629 aa)
	TMEM185A	Transmembrane protein 185A. (341 aa)
	RUFY3	RUN and FYVE domain containing 3. (635 aa)
	CDKL5	Cyclin dependent kinase like 5. (644 aa)
	GIGYF2	GRB10 interacting GYF protein 2. (1285 aa)
	TRPV1	Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (838 aa)
	TRPV4	Transient receptor potential cation channel subfamily V member 4. (854 aa)
	NF1	Neurofibromin 1. (2788 aa)
	PSEN2	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (387 aa)
	PPP1R9A	Protein phosphatase 1 regulatory subunit 9A. (1114 aa)
	STUM	Stum, mechanosensory transduction mediator homolog. (102 aa)
	K7GGH9_PELSI	ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (648 aa)
	TRPV3	Transient receptor potential cation channel subfamily V member 3; Belongs to the transient receptor (TC 1.A.4) family. (791 aa)
	CTTNBP2	Cortactin binding protein 2. (1609 aa)
	GPHN	Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (729 aa)
	DRD1	Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (451 aa)
	K7EWG1_PELSI	Uncharacterized protein. (58 aa)
	CCIN	Calicin. (588 aa)
	TMEM60	Transmembrane protein 60. (134 aa)
	ABHD13	Abhydrolase domain containing 13. (337 aa)
	K7F0I3_PELSI	Uncharacterized protein; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (307 aa)
	LOC102443870	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (416 aa)
	GPER1	G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (369 aa)
	ZNF804A	Zinc finger protein 804A. (1123 aa)
	NPAS4	Uncharacterized protein. (479 aa)
	FARP1	Uncharacterized protein. (952 aa)
	LOC102446337	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (442 aa)
	FRMPD1	Uncharacterized protein. (435 aa)
	KCND3	DUF3399 domain-containing protein. (233 aa)
	KCND3-2	BTB domain-containing protein; Belongs to the potassium channel family. (447 aa)
	TMEM222	Transmembrane protein 222. (143 aa)
	KNDC1	Kinase non-catalytic C-lobe domain containing 1. (1123 aa)
	K7F890_PELSI	Peptidase_M23 domain-containing protein. (144 aa)
	COBL	Cordon-bleu WH2 repeat protein. (1408 aa)
	VSTM5	V-set and transmembrane domain containing 5. (200 aa)
	SLC4A10	Anion exchange protein. (1130 aa)
	NEURL1	Neuralized E3 ubiquitin protein ligase 1. (572 aa)
	LOC102452665	DHR-2 domain-containing protein; Belongs to the DOCK family. (1239 aa)
	KCND2	Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family. (369 aa)
	K7FFP0_PELSI	DUF3399 domain-containing protein. (127 aa)
	ABR	Rho-GAP domain-containing protein. (117 aa)
	PSEN1	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
	NOS1	Nitric oxide synthase 1. (1437 aa)
	PALMD	Palmdelphin. (553 aa)
	BRINP2	BMP/retinoic acid inducible neural specific 2. (775 aa)
	CNIH3	Cornichon family AMPA receptor auxiliary protein 3. (160 aa)
	TANC2	Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2. (1916 aa)
	BCR	BCR activator of RhoGEF and GTPase. (1293 aa)
	TRIM9	Tripartite motif containing 9. (472 aa)
	ADCY8	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1070 aa)
	FXR1	FMR1 autosomal homolog 1. (672 aa)
	K7FK98_PELSI	Uncharacterized protein. (100 aa)
	BRINP3	MACPF domain-containing protein. (696 aa)
	GRID2IP	Grid2 interacting protein. (1011 aa)
	ATCAY	ATCAY kinesin light chain interacting caytaxin. (361 aa)
	FXR2	FMR1 autosomal homolog 2. (644 aa)
	NSMF	NMDA receptor synaptonuclear signaling and neuronal migration factor. (525 aa)
	K7FNA0_PELSI	Uncharacterized protein. (111 aa)
	OPHN1	Oligophrenin 1. (801 aa)
	GRIP2	Glutamate receptor interacting protein 2. (564 aa)
	FMR1	Fragile X mental retardation 1. (561 aa)

Your Current Organism:

Pelodiscus sinensis

NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY3	ADCY8	ENSPSIP00000010430	ENSPSIP00000008407	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.610
ADCY8	ADCY3	ENSPSIP00000008407	ENSPSIP00000010430	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.610
CDKL5	FMR1	ENSPSIP00000014123	ENSPSIP00000010080	Cyclin dependent kinase like 5.	Fragile X mental retardation 1.	0.564
CRHBP	SST	ENSPSIP00000014861	ENSPSIP00000016361	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.	Somatostatin.	0.472
FMR1	CDKL5	ENSPSIP00000010080	ENSPSIP00000014123	Fragile X mental retardation 1.	Cyclin dependent kinase like 5.	0.564
FMR1	FXR1	ENSPSIP00000010080	ENSPSIP00000008435	Fragile X mental retardation 1.	FMR1 autosomal homolog 1.	0.958
FMR1	FXR2	ENSPSIP00000010080	ENSPSIP00000009051	Fragile X mental retardation 1.	FMR1 autosomal homolog 2.	0.958
FXR1	FMR1	ENSPSIP00000008435	ENSPSIP00000010080	FMR1 autosomal homolog 1.	Fragile X mental retardation 1.	0.958
FXR1	FXR2	ENSPSIP00000008435	ENSPSIP00000009051	FMR1 autosomal homolog 1.	FMR1 autosomal homolog 2.	0.901
FXR2	FMR1	ENSPSIP00000009051	ENSPSIP00000010080	FMR1 autosomal homolog 2.	Fragile X mental retardation 1.	0.958
FXR2	FXR1	ENSPSIP00000009051	ENSPSIP00000008435	FMR1 autosomal homolog 2.	FMR1 autosomal homolog 1.	0.901
GPER1	SST	ENSPSIP00000001724	ENSPSIP00000016361	G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family.	Somatostatin.	0.563
GPHN	PVALB	ENSPSIP00000018826	ENSPSIP00000010993	Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.	Parvalbumin; Belongs to the parvalbumin family.	0.605
K7FFP0_PELSI	KCND2	ENSPSIP00000006850	ENSPSIP00000006838	DUF3399 domain-containing protein.	Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family.	0.497
K7FFP0_PELSI	KCND3-2	ENSPSIP00000006850	ENSPSIP00000003850	DUF3399 domain-containing protein.	BTB domain-containing protein; Belongs to the potassium channel family.	0.461
K7FNA0_PELSI	TANC2	ENSPSIP00000009510	ENSPSIP00000007926	Uncharacterized protein.	Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2.	0.896
K7G225_PELSI	LOC102452665	ENSPSIP00000014336	ENSPSIP00000006071	PH domain-containing protein.	DHR-2 domain-containing protein; Belongs to the DOCK family.	0.888
KCND2	K7FFP0_PELSI	ENSPSIP00000006838	ENSPSIP00000006850	Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family.	DUF3399 domain-containing protein.	0.497
KCND2	KCND3	ENSPSIP00000006838	ENSPSIP00000003843	Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family.	DUF3399 domain-containing protein.	0.858
KCND3	KCND2	ENSPSIP00000003843	ENSPSIP00000006838	DUF3399 domain-containing protein.	Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family.	0.858