(26 nodes) Toll/interleukin-1 receptor homology (TIR) domain superfamily network (Pelodiscus sinensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	IL1RAPL1	Interleukin 1 receptor accessory protein like 1. (669 aa)
	TIRAP	TIR domain containing adaptor protein. (232 aa)
	K7G601_PELSI	TIR domain-containing protein. (888 aa)
	K7G218_PELSI	TIR domain-containing protein; Belongs to the Toll-like receptor family. (1043 aa)
	TLR6	Toll-like receptor. (653 aa)
	IL18R1	Interleukin 18 receptor 1. (569 aa)
	TLR3	Toll like receptor 3; Belongs to the Toll-like receptor family. (896 aa)
	IL1RAPL2	Interleukin 1 receptor accessory protein like 2. (658 aa)
	TLR8	TIR domain-containing protein; Belongs to the Toll-like receptor family. (1037 aa)
	IL1RL1	Interleukin 1 receptor like 1. (547 aa)
	MYD88	MYD88 innate immune signal transduction adaptor. (186 aa)
	IL17RD	Interleukin 17 receptor D. (740 aa)
	LOC102457570	TIR domain-containing protein; Belongs to the Toll-like receptor family. (783 aa)
	TLR5	TIR domain-containing protein. (860 aa)
	TLR2	TIR domain-containing protein; Belongs to the Toll-like receptor family. (783 aa)
	TLR7	Toll like receptor 7; Belongs to the Toll-like receptor family. (1050 aa)
	LOC102461996	TIR domain-containing protein; Belongs to the Toll-like receptor family. (925 aa)
	SARM1	Sterile alpha and TIR motif containing 1. (712 aa)
	LOC102463929	Uncharacterized protein. (436 aa)
	LOC102463419	Uncharacterized protein. (547 aa)
	K7GFU7_PELSI	Uncharacterized protein. (555 aa)
	TICAM2	TIR domain-containing protein. (170 aa)
	SIGIRR	Single Ig and TIR domain containing. (434 aa)
	IL18RAP	Interleukin 18 receptor accessory protein. (584 aa)
	IL1RAP	Interleukin 1 receptor accessory protein. (681 aa)
	TLR4	Toll like receptor 4; Belongs to the Toll-like receptor family. (833 aa)

Your Current Organism:

Pelodiscus sinensis

NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IL18R1	IL1RAP	ENSPSIP00000012682	ENSPSIP00000005779	Interleukin 18 receptor 1.	Interleukin 1 receptor accessory protein.	0.590
IL18R1	SIGIRR	ENSPSIP00000012682	ENSPSIP00000008042	Interleukin 18 receptor 1.	Single Ig and TIR domain containing.	0.608
IL1RAP	IL18R1	ENSPSIP00000005779	ENSPSIP00000012682	Interleukin 1 receptor accessory protein.	Interleukin 18 receptor 1.	0.590
IL1RAP	IL1RAPL2	ENSPSIP00000005779	ENSPSIP00000011850	Interleukin 1 receptor accessory protein.	Interleukin 1 receptor accessory protein like 2.	0.835
IL1RAP	IL1RL1	ENSPSIP00000005779	ENSPSIP00000010424	Interleukin 1 receptor accessory protein.	Interleukin 1 receptor like 1.	0.965
IL1RAP	K7GFU7_PELSI	ENSPSIP00000005779	ENSPSIP00000019158	Interleukin 1 receptor accessory protein.	Uncharacterized protein.	0.840
IL1RAP	LOC102463419	ENSPSIP00000005779	ENSPSIP00000019377	Interleukin 1 receptor accessory protein.	Uncharacterized protein.	0.840
IL1RAP	LOC102463929	ENSPSIP00000005779	ENSPSIP00000019412	Interleukin 1 receptor accessory protein.	Uncharacterized protein.	0.840
IL1RAP	MYD88	ENSPSIP00000005779	ENSPSIP00000008979	Interleukin 1 receptor accessory protein.	MYD88 innate immune signal transduction adaptor.	0.814
IL1RAPL2	IL1RAP	ENSPSIP00000011850	ENSPSIP00000005779	Interleukin 1 receptor accessory protein like 2.	Interleukin 1 receptor accessory protein.	0.835
IL1RL1	IL1RAP	ENSPSIP00000010424	ENSPSIP00000005779	Interleukin 1 receptor like 1.	Interleukin 1 receptor accessory protein.	0.965
IL1RL1	MYD88	ENSPSIP00000010424	ENSPSIP00000008979	Interleukin 1 receptor like 1.	MYD88 innate immune signal transduction adaptor.	0.762
K7G218_PELSI	K7G601_PELSI	ENSPSIP00000014329	ENSPSIP00000015712	TIR domain-containing protein; Belongs to the Toll-like receptor family.	TIR domain-containing protein.	0.495
K7G218_PELSI	LOC102461996	ENSPSIP00000014329	ENSPSIP00000000251	TIR domain-containing protein; Belongs to the Toll-like receptor family.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.546
K7G218_PELSI	MYD88	ENSPSIP00000014329	ENSPSIP00000008979	TIR domain-containing protein; Belongs to the Toll-like receptor family.	MYD88 innate immune signal transduction adaptor.	0.978
K7G218_PELSI	TICAM2	ENSPSIP00000014329	ENSPSIP00000019141	TIR domain-containing protein; Belongs to the Toll-like receptor family.	TIR domain-containing protein.	0.408
K7G218_PELSI	TIRAP	ENSPSIP00000014329	ENSPSIP00000015944	TIR domain-containing protein; Belongs to the Toll-like receptor family.	TIR domain containing adaptor protein.	0.627
K7G218_PELSI	TLR3	ENSPSIP00000014329	ENSPSIP00000012134	TIR domain-containing protein; Belongs to the Toll-like receptor family.	Toll like receptor 3; Belongs to the Toll-like receptor family.	0.629
K7G218_PELSI	TLR5	ENSPSIP00000014329	ENSPSIP00000000534	TIR domain-containing protein; Belongs to the Toll-like receptor family.	TIR domain-containing protein.	0.527
K7G218_PELSI	TLR7	ENSPSIP00000014329	ENSPSIP00000000410	TIR domain-containing protein; Belongs to the Toll-like receptor family.	Toll like receptor 7; Belongs to the Toll-like receptor family.	0.587