STRINGSTRING
RFC5 RFC5 ATAD5 ATAD5 POLE3 POLE3 RPA1 RPA1 POLE POLE USP1 USP1 CUL4B CUL4B RFC4 RFC4 POLD2 POLD2 RAD18 RAD18 POLE2 POLE2 RFC2 RFC2 DDB1 DDB1 CUL4A CUL4A K7G6G0_PELSI K7G6G0_PELSI RFC3 RFC3 POLD3 POLD3 K7EXK2_PELSI K7EXK2_PELSI PCNA PCNA RCBTB1 RCBTB1 UBC UBC WDR48 WDR48 RPA3 RPA3 MEIOB MEIOB RPS27A RPS27A RCBTB2 RCBTB2 DTL DTL KXD1 KXD1 UBA52 UBA52 RFC1 RFC1 RBX1 RBX1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RFC5Replication factor C subunit 5. (319 aa)
ATAD5ATPase family AAA domain containing 5. (1692 aa)
POLE3CBFD_NFYB_HMF domain-containing protein. (141 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (603 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2166 aa)
USP1Ubiquitin specific peptidase 1; Belongs to the peptidase C19 family. (668 aa)
CUL4BCullin 4B; Belongs to the cullin family. (913 aa)
RFC4Replication factor C subunit 4. (329 aa)
POLD2DNA polymerase delta 2, accessory subunit. (470 aa)
RAD18RAD18 E3 ubiquitin protein ligase. (500 aa)
POLE2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa)
RFC2Replication factor C subunit 2. (374 aa)
DDB1Damage specific DNA binding protein 1. (1124 aa)
CUL4ACULLIN_2 domain-containing protein; Belongs to the cullin family. (571 aa)
K7G6G0_PELSICULLIN_2 domain-containing protein; Belongs to the cullin family. (189 aa)
RFC3Replication factor C subunit 3. (304 aa)
POLD3Uncharacterized protein. (420 aa)
K7EXK2_PELSIUbiquitin-like domain-containing protein. (32 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (262 aa)
RCBTB1RCC1 and BTB domain containing protein 1. (531 aa)
UBCUncharacterized protein. (355 aa)
WDR48WD repeat domain 48. (682 aa)
RPA3Replication protein A3. (119 aa)
MEIOBMeiosis specific with OB-fold. (467 aa)
RPS27AUbiquitin-like domain-containing protein. (140 aa)
RCBTB2RCC1 and BTB domain containing protein 2. (552 aa)
DTLDenticleless E3 ubiquitin protein ligase homolog. (680 aa)
KXD1KxDL motif containing 1. (176 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
RFC1Replication factor C subunit 1. (1146 aa)
RBX1Ring-box 1. (120 aa)
Your Current Organism:
Pelodiscus sinensis
NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.