69 items (Pelodiscus sinensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	K7FCZ0_PELSI	Uncharacterized protein. (410 aa)
	K7F708_PELSI	A2M_N_2 domain-containing protein. (530 aa)
	SAR1B	Secretion associated Ras related GTPase 1B; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
	APOA2	Uncharacterized protein. (103 aa)
	ZDHHC5	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (722 aa)
	K7FE86_PELSI	Uncharacterized protein. (141 aa)
	LOC102444059	Vitellogenin domain-containing protein. (861 aa)
	K7FFP8_PELSI	TED_complement domain-containing protein. (631 aa)
	LMF1	Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family. (563 aa)
	APOB	Apolipoprotein B. (4628 aa)
	PRKACB	Uncharacterized protein; Belongs to the protein kinase superfamily. (398 aa)
	AP2S1	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (122 aa)
	NCEH1	Neutral cholesterol ester hydrolase 1. (444 aa)
	MTTP	Microsomal triglyceride transfer protein. (893 aa)
	LDLRAP1	Low density lipoprotein receptor adaptor protein 1. (179 aa)
	LSR	Lipolysis stimulated lipoprotein receptor. (409 aa)
	MYLIP	Myosin regulatory light chain interacting protein. (419 aa)
	ANGPTL4	Angiopoietin like 4. (324 aa)
	PTCHD3	SSD domain-containing protein. (556 aa)
	LCAT	Lecithin-cholesterol acyltransferase. (309 aa)
	K7FSP2_PELSI	Uncharacterized protein. (1238 aa)
	PDIA2	Protein disulfide isomerase family A member 2. (348 aa)
	P4HB	Protein disulfide-isomerase. (450 aa)
	K7GHB6_PELSI	A2M_N_2 domain-containing protein. (446 aa)
	PLG	Uncharacterized protein; Belongs to the peptidase S1 family. (835 aa)
	LOC102451496	Uncharacterized protein. (1085 aa)
	K7GGJ3_PELSI	Vitellogenin domain-containing protein. (743 aa)
	K7GGC3_PELSI	Uncharacterized protein. (543 aa)
	K7GG70_PELSI	Uncharacterized protein. (1845 aa)
	ANGPTL3	Angiopoietin like 3. (461 aa)
	NPC2	NPC intracellular cholesterol transporter 2. (148 aa)
	LPL	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (469 aa)
	HDLBP	High density lipoprotein binding protein. (1159 aa)
	NR1H3	Nuclear receptor subfamily 1 group H member 3. (409 aa)
	UBA52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	CETP	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. (500 aa)
	KXD1	KxDL motif containing 1. (176 aa)
	K7FXH4_PELSI	Uncharacterized protein. (935 aa)
	APOA1	Apolipoprotein A1. (261 aa)
	PLEKHD1	Pleckstrin homology and coiled-coil domain containing D1. (503 aa)
	CLHC1	Clathrin heavy chain linker domain-containing protein 1. (590 aa)
	RPS27A	Ubiquitin-like domain-containing protein. (140 aa)
	APOA4	Apolipoprotein A4. (367 aa)
	PRKACA	Uncharacterized protein; Belongs to the protein kinase superfamily. (340 aa)
	SMPDL3A	Sphingomyelin phosphodiesterase acid like 3A. (420 aa)
	APOA5	Apolipoprotein A5. (364 aa)
	CUBN	Cubilin. (3680 aa)
	LOC102459126	SSD domain-containing protein. (768 aa)
	K7G555_PELSI	MG3 domain-containing protein. (105 aa)
	PCSK6	Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (875 aa)
	K7G5Y1_PELSI	Uncharacterized protein. (131 aa)
	LIPC	Lipase C, hepatic type. (498 aa)
	SAR1A	Secretion associated Ras related GTPase 1A; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
	PCSK5	Proprotein convertase subtilisin/kexin type 5; Belongs to the peptidase S8 family. (915 aa)
	PTCHD4	Uncharacterized protein. (350 aa)
	AP2A2	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (946 aa)
	PTCHD1	Patched domain containing 1. (488 aa)
	A2ML1	Alpha-2-macroglobulin like 1. (1451 aa)
	AMN	Amnion associated transmembrane protein. (481 aa)
	AP2M1	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (433 aa)
	K7GD29_PELSI	Uncharacterized protein. (1489 aa)
	K7EXK2_PELSI	Ubiquitin-like domain-containing protein. (32 aa)
	ZDHHC8	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (714 aa)
	PCSK4	Proprotein convertase subtilisin/kexin type 4. (599 aa)
	LMF2	Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family. (666 aa)
	CDCP2	CUB domain containing protein 2. (441 aa)
	SCARB1	Scavenger receptor class B member 1; Belongs to the CD36 family. (454 aa)
	UBC	Uncharacterized protein. (355 aa)
	PCSK9	Proprotein convertase subtilisin/kexin type 9. (690 aa)

Your Current Organism:

Pelodiscus sinensis

NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMN	CDCP2	ENSPSIP00000016487	ENSPSIP00000003088	Amnion associated transmembrane protein.	CUB domain containing protein 2.	0.896
AMN	CUBN	ENSPSIP00000016487	ENSPSIP00000015092	Amnion associated transmembrane protein.	Cubilin.	0.977
ANGPTL3	APOA5	ENSPSIP00000018543	ENSPSIP00000014942	Angiopoietin like 3.	Apolipoprotein A5.	0.609
ANGPTL3	APOB	ENSPSIP00000018543	ENSPSIP00000007565	Angiopoietin like 3.	Apolipoprotein B.	0.612
ANGPTL3	K7GGC3_PELSI	ENSPSIP00000018543	ENSPSIP00000019334	Angiopoietin like 3.	Uncharacterized protein.	0.452
ANGPTL3	PCSK9	ENSPSIP00000018543	ENSPSIP00000003667	Angiopoietin like 3.	Proprotein convertase subtilisin/kexin type 9.	0.419
AP2A2	AP2M1	ENSPSIP00000016265	ENSPSIP00000017064	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	0.998
AP2A2	AP2S1	ENSPSIP00000016265	ENSPSIP00000007963	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.998
AP2A2	K7EXK2_PELSI	ENSPSIP00000016265	ENSPSIP00000000512	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	Ubiquitin-like domain-containing protein.	0.424
AP2A2	PCSK9	ENSPSIP00000016265	ENSPSIP00000003667	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	Proprotein convertase subtilisin/kexin type 9.	0.426
AP2A2	RPS27A	ENSPSIP00000016265	ENSPSIP00000014184	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	Ubiquitin-like domain-containing protein.	0.568
AP2A2	SCARB1	ENSPSIP00000016265	ENSPSIP00000003334	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	Scavenger receptor class B member 1; Belongs to the CD36 family.	0.419
AP2A2	UBA52	ENSPSIP00000016265	ENSPSIP00000012408	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.452
AP2A2	UBC	ENSPSIP00000016265	ENSPSIP00000003340	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	Uncharacterized protein.	0.575
AP2M1	AP2A2	ENSPSIP00000017064	ENSPSIP00000016265	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.998
AP2M1	AP2S1	ENSPSIP00000017064	ENSPSIP00000007963	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.999
AP2M1	APOB	ENSPSIP00000017064	ENSPSIP00000007565	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Apolipoprotein B.	0.534
AP2M1	CLHC1	ENSPSIP00000017064	ENSPSIP00000014173	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Clathrin heavy chain linker domain-containing protein 1.	0.743
AP2M1	K7EXK2_PELSI	ENSPSIP00000017064	ENSPSIP00000000512	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Ubiquitin-like domain-containing protein.	0.578
AP2M1	K7GGC3_PELSI	ENSPSIP00000017064	ENSPSIP00000019334	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Uncharacterized protein.	0.430