STRINGSTRING
POLR2D POLR2D RBFOX2 RBFOX2 FGF5 FGF5 FGF16 FGF16 POLR2H POLR2H FRS2 FRS2 POLR2C POLR2C MKNK2 MKNK2 KRAS KRAS HRAS HRAS FGF1 FGF1 PIK3CA PIK3CA PTBP1 PTBP1 POLR2A POLR2A LOC102443910 LOC102443910 K7G5M9_PELSI K7G5M9_PELSI POLR2F POLR2F POLR2L POLR2L TIAL1 TIAL1 TIA1 TIA1 PPP2CB PPP2CB SOS1 SOS1 RPS27A RPS27A K7FZH9_PELSI K7FZH9_PELSI FGF2 FGF2 FGF18 FGF18 HNRNPM HNRNPM POLR2I POLR2I BRAF BRAF FGF23 FGF23 FGF6 FGF6 UBA52 UBA52 FGF20 FGF20 STIL STIL SPRY2 SPRY2 LOC102453643 LOC102453643 FGFR3 FGFR3 FGFRL1 FGFRL1 NCBP1 NCBP1 K7FR43_PELSI K7FR43_PELSI FGF19 FGF19 GRB2 GRB2 FGF4 FGF4 FGF7 FGF7 SPRED2 SPRED2 FGF3 FGF3 K7FMW9_PELSI K7FMW9_PELSI PTBP3 PTBP3 FGF8 FGF8 FGF9 FGF9 FGFR2 FGFR2 FGF17 FGF17 FRS3 FRS3 GTF2F1 GTF2F1 K7FJ02_PELSI K7FJ02_PELSI K7FIQ5_PELSI K7FIQ5_PELSI PTBP2 PTBP2 FNDC3B FNDC3B K7FGG7_PELSI K7FGG7_PELSI SPRED1 SPRED1 FGFR1 FGFR1 LOC102447645 LOC102447645 PPP2CA PPP2CA ANOS1 ANOS1 POLR2G POLR2G FGF10 FGF10 POLR2K POLR2K GAB1 GAB1 CSDE1 CSDE1 NRAS NRAS PTPN11 PTPN11 ESRP2 ESRP2 UBC UBC MKNK1 MKNK1 POLR2B POLR2B POLR2E POLR2E FLRT2 FLRT2 ESRP1 ESRP1 FNDC3A FNDC3A FLRT1 FLRT1 FLRT3 FLRT3 K7EZ08_PELSI K7EZ08_PELSI SPRY3 SPRY3 K7EYU4_PELSI K7EYU4_PELSI K7EXK2_PELSI K7EXK2_PELSI FGFBP1 FGFBP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
POLR2DRNA polymerase II subunit D. (118 aa)
RBFOX2RNA binding protein fox-1 homolog 2; RNA-binding protein that regulates alternative splicing events. (398 aa)
FGF5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (251 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
POLR2HRNA polymerase II subunit H. (114 aa)
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)
POLR2CRNA polymerase II subunit C. (272 aa)
MKNK2MAPK interacting serine/threonine kinase 2; Belongs to the protein kinase superfamily. (467 aa)
KRASKRAS proto-oncogene, GTPase. (227 aa)
HRASHRas proto-oncogene, GTPase. (190 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1029 aa)
PTBP1Polypyrimidine tract binding protein 1. (577 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1634 aa)
LOC102443910Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
K7G5M9_PELSIUncharacterized protein. (120 aa)
POLR2FRNA polymerase II subunit F. (71 aa)
POLR2LRNA polymerase II subunit L. (67 aa)
TIAL1Uncharacterized protein. (430 aa)
TIA1TIA1 cytotoxic granule associated RNA binding protein. (373 aa)
PPP2CBSerine/threonine-protein phosphatase. (307 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1304 aa)
RPS27AUbiquitin-like domain-containing protein. (140 aa)
K7FZH9_PELSIUncharacterized protein. (310 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (97 aa)
FGF18Fibroblast growth factor 18; Belongs to the heparin-binding growth factors family. (204 aa)
HNRNPMHeterogeneous nuclear ribonucleoprotein M. (667 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (103 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (760 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (250 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (215 aa)
STILSTIL centriolar assembly protein. (1327 aa)
SPRY2Sprouty RTK signaling antagonist 2. (313 aa)
LOC102453643RNA polymerase II subunit J. (100 aa)
FGFR3Fibroblast growth factor receptor. (827 aa)
FGFRL1Fibroblast growth factor receptor like 1. (487 aa)
NCBP1Nuclear cap binding protein subunit 1. (512 aa)
K7FR43_PELSINuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (132 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (223 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (192 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
SPRED2Sprouty related EVH1 domain containing 2. (410 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (235 aa)
K7FMW9_PELSINuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (140 aa)
PTBP3Polypyrimidine tract binding protein 3. (539 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (228 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
FGFR2Fibroblast growth factor receptor. (815 aa)
FGF17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
FRS3Fibroblast growth factor receptor substrate 3; Belongs to the peptidase A1 family. (738 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (511 aa)
K7FJ02_PELSIPhosphatidylinositol 3-kinase catalytic subunit type 3. (787 aa)
K7FIQ5_PELSIPI3K-ABD domain-containing protein; Belongs to the PI3/PI4-kinase family. (211 aa)
PTBP2Polypyrimidine tract binding protein 2. (588 aa)
FNDC3BFibronectin type III domain containing 3B. (1211 aa)
K7FGG7_PELSIUncharacterized protein. (738 aa)
SPRED1Sprouty related EVH1 domain containing 1. (213 aa)
FGFR1Fibroblast growth factor receptor. (820 aa)
LOC102447645Uncharacterized protein. (227 aa)
PPP2CASerine/threonine-protein phosphatase. (244 aa)
ANOS1Anosmin 1. (678 aa)
POLR2GRNA polymerase II subunit G. (210 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
POLR2KRNA polymerase II subunit K. (58 aa)
GAB1GRB2 associated binding protein 1. (687 aa)
CSDE1Cold shock domain containing E1. (471 aa)
NRASNRAS proto-oncogene, GTPase. (123 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (591 aa)
ESRP2Epithelial splicing regulatory protein 2. (708 aa)
UBCUncharacterized protein. (355 aa)
MKNK1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (471 aa)
POLR2BRNA polymerase II subunit B; Belongs to the RNA polymerase beta chain family. (800 aa)
POLR2ERNA polymerase II subunit E. (208 aa)
FLRT2Fibronectin leucine rich transmembrane protein 2. (661 aa)
ESRP1Epithelial splicing regulatory protein 1. (427 aa)
FNDC3AFibronectin type III domain containing 3A. (1142 aa)
FLRT1Fibronectin leucine rich transmembrane protein 1. (661 aa)
FLRT3Fibronectin leucine rich transmembrane protein 3. (649 aa)
K7EZ08_PELSIUncharacterized protein. (281 aa)
SPRY3Sprouty RTK signaling antagonist 3. (290 aa)
K7EYU4_PELSIUncharacterized protein. (249 aa)
K7EXK2_PELSIUbiquitin-like domain-containing protein. (32 aa)
FGFBP1Fibroblast growth factor binding protein 1. (252 aa)
Your Current Organism:
Pelodiscus sinensis
NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38
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