(87 nodes) Cytochrome P450 - arranged by substrate type network (Pelodiscus sinensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102448631	Uncharacterized protein. (294 aa)
	K7GJN0_PELSI	Uncharacterized protein. (581 aa)
	CYP26A1	Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family. (453 aa)
	CYP19A1	Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family. (503 aa)
	CYP26C1	Cytochrome P450 family 26 subfamily C member 1; Belongs to the cytochrome P450 family. (526 aa)
	K7GI26_PELSI	Uncharacterized protein; Belongs to the cytochrome P450 family. (494 aa)
	CYP51A1	Cytochrome P450 family 51 subfamily A member 1; Belongs to the cytochrome P450 family. (502 aa)
	CYP20A1	Cytochrome P450 family 20 subfamily A member 1. (461 aa)
	K7GFR4_PELSI	Uncharacterized protein; Belongs to the cytochrome P450 family. (330 aa)
	K7GFK2_PELSI	Uncharacterized protein. (401 aa)
	K7GFE0_PELSI	Uncharacterized protein; Belongs to the cytochrome P450 family. (494 aa)
	CYP24A1	Cytochrome P450 family 24 subfamily A member 1; Belongs to the cytochrome P450 family. (472 aa)
	CYP7B1	Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. (502 aa)
	CYP27B1	Cytochrome P450 family 27 subfamily B member 1. (469 aa)
	CYP39A1	Cytochrome P450 family 39 subfamily A member 1; Belongs to the cytochrome P450 family. (470 aa)
	K7GC00_PELSI	Uncharacterized protein; Belongs to the cytochrome P450 family. (479 aa)
	CYP27C1	Cytochrome P450 family 27 subfamily C member 1; Belongs to the cytochrome P450 family. (496 aa)
	CCNDBP1	Cyclin D1 binding protein 1. (233 aa)
	K7G9Q4_PELSI	Uncharacterized protein. (174 aa)
	TBXAS1	Uncharacterized protein; Belongs to the cytochrome P450 family. (297 aa)
	LOC102446167	Uncharacterized protein; Belongs to the cytochrome P450 family. (276 aa)
	CYP46A1	Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family. (485 aa)
	LOC102462071	2Fe-2S ferredoxin-type domain-containing protein. (182 aa)
	LOC102460160	Uncharacterized protein; Belongs to the cytochrome P450 family. (522 aa)
	K7G4D0_PELSI	Uncharacterized protein; Belongs to the cytochrome P450 family. (491 aa)
	LOC102451013	Uncharacterized protein. (501 aa)
	CYP11A1	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (554 aa)
	K7G3S1_PELSI	Uncharacterized protein. (498 aa)
	CYP26B1	Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (488 aa)
	K7G2G6_PELSI	Uncharacterized protein. (509 aa)
	K7G0D6_PELSI	Uncharacterized protein; Belongs to the cytochrome P450 family. (504 aa)
	K7G035_PELSI	Uncharacterized protein. (350 aa)
	K7G034_PELSI	Uncharacterized protein. (376 aa)
	K7FZF9_PELSI	Uncharacterized protein. (507 aa)
	CYP2R1	Cytochrome P450 family 2 subfamily R member 1; Belongs to the cytochrome P450 family. (497 aa)
	TTI2	TELO2 interacting protein 2. (510 aa)
	POMC	Proopiomelanocortin. (261 aa)
	K7FVH1_PELSI	Uncharacterized protein. (510 aa)
	ARNT2	Aryl hydrocarbon receptor nuclear translocator 2. (725 aa)
	CYP4F22	Cytochrome P450 family 4 subfamily F member 22; Belongs to the cytochrome P450 family. (364 aa)
	PTGIS	Prostaglandin I2 synthase; Belongs to the cytochrome P450 family. (456 aa)
	AHR	Uncharacterized protein. (831 aa)
	LOC102460248	Uncharacterized protein; Belongs to the cytochrome P450 family. (525 aa)
	LOC102462176	Uncharacterized protein; Belongs to the cytochrome P450 family. (507 aa)
	LOC102447714	Uncharacterized protein. (522 aa)
	K7FR97_PELSI	Uncharacterized protein; Belongs to the cytochrome P450 family. (463 aa)
	FDX1	Ferredoxin 1. (123 aa)
	K7FP12_PELSI	Uncharacterized protein; Belongs to the cytochrome P450 family. (495 aa)
	LOC102455815	Uncharacterized protein; Belongs to the cytochrome P450 family. (513 aa)
	LOC102447293	Uncharacterized protein. (510 aa)
	K7FN96_PELSI	Uncharacterized protein. (133 aa)
	K7FN89_PELSI	Uncharacterized protein. (164 aa)
	ARNT	Aryl hydrocarbon receptor nuclear translocator. (793 aa)
	K7FMM2_PELSI	Uncharacterized protein; Belongs to the cytochrome P450 family. (549 aa)
	K7FMI1_PELSI	Uncharacterized protein. (187 aa)
	K7FLX9_PELSI	Uncharacterized protein. (217 aa)
	LOC102459847	Uncharacterized protein; Belongs to the cytochrome P450 family. (494 aa)
	LOC102461775	Uncharacterized protein; Belongs to the cytochrome P450 family. (146 aa)
	FDXR	NADPH:adrenodoxin oxidoreductase, mitochondrial. (500 aa)
	LOC102455640	Uncharacterized protein; Belongs to the cytochrome P450 family. (530 aa)
	CYP7A1	Cytochrome P450 family 7 subfamily A member 1. (514 aa)
	LOC102457583	Uncharacterized protein; Belongs to the cytochrome P450 family. (494 aa)
	AHRR	Uncharacterized protein. (549 aa)
	K7FI64_PELSI	Uncharacterized protein. (180 aa)
	LOC102455397	Uncharacterized protein; Belongs to the cytochrome P450 family. (631 aa)
	CBFA2T2	CBFA2/RUNX1 partner transcriptional co-repressor 2. (580 aa)
	CYP2U1	Cytochrome P450 family 2 subfamily U member 1; Belongs to the cytochrome P450 family. (518 aa)
	NR1H4	Nuclear receptor subfamily 1 group H member 4. (450 aa)
	CYP1B1	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (536 aa)
	K7FBW5_PELSI	Uncharacterized protein; Belongs to the cytochrome P450 family. (488 aa)
	K7FBD5_PELSI	Uncharacterized protein. (119 aa)
	K7FBC7_PELSI	Uncharacterized protein. (209 aa)
	K7FB82_PELSI	Uncharacterized protein. (133 aa)
	CYP2J19	Uncharacterized protein; Belongs to the cytochrome P450 family. (499 aa)
	K7FAG8_PELSI	Uncharacterized protein; Belongs to the cytochrome P450 family. (547 aa)
	FADS6	Fatty acid desaturase 6. (464 aa)
	LOC102458597	Uncharacterized protein; Belongs to the cytochrome P450 family. (494 aa)
	LOC102449041	Uncharacterized protein. (513 aa)
	K7F7J1_PELSI	Uncharacterized protein. (279 aa)
	CBFA2T3	Uncharacterized protein. (447 aa)
	LOC102452942	Uncharacterized protein. (519 aa)
	K7F4U7_PELSI	Uncharacterized protein. (192 aa)
	LOC102452682	Uncharacterized protein; Belongs to the cytochrome P450 family. (322 aa)
	LOC102452267	Uncharacterized protein. (518 aa)
	CYP8B1	Cytochrome P450 family 8 subfamily B member 1; Belongs to the cytochrome P450 family. (482 aa)
	RUNX1T1	RUNX1 partner transcriptional co-repressor 1. (603 aa)
	CCDC160	Coiled-coil domain containing 160. (323 aa)

Your Current Organism:

Pelodiscus sinensis

NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AHR	ARNT	ENSPSIP00000011268	ENSPSIP00000009433	Uncharacterized protein.	Aryl hydrocarbon receptor nuclear translocator.	0.893
AHR	ARNT2	ENSPSIP00000011268	ENSPSIP00000011844	Uncharacterized protein.	Aryl hydrocarbon receptor nuclear translocator 2.	0.928
AHRR	ARNT	ENSPSIP00000007799	ENSPSIP00000009433	Uncharacterized protein.	Aryl hydrocarbon receptor nuclear translocator.	0.664
AHRR	ARNT2	ENSPSIP00000007799	ENSPSIP00000011844	Uncharacterized protein.	Aryl hydrocarbon receptor nuclear translocator 2.	0.664
AHRR	K7FI64_PELSI	ENSPSIP00000007799	ENSPSIP00000007724	Uncharacterized protein.	Uncharacterized protein.	0.886
ARNT	AHR	ENSPSIP00000009433	ENSPSIP00000011268	Aryl hydrocarbon receptor nuclear translocator.	Uncharacterized protein.	0.893
ARNT	AHRR	ENSPSIP00000009433	ENSPSIP00000007799	Aryl hydrocarbon receptor nuclear translocator.	Uncharacterized protein.	0.664
ARNT	K7FI64_PELSI	ENSPSIP00000009433	ENSPSIP00000007724	Aryl hydrocarbon receptor nuclear translocator.	Uncharacterized protein.	0.664
ARNT	K7GJN0_PELSI	ENSPSIP00000009433	ENSPSIP00000020491	Aryl hydrocarbon receptor nuclear translocator.	Uncharacterized protein.	0.893
ARNT2	AHR	ENSPSIP00000011844	ENSPSIP00000011268	Aryl hydrocarbon receptor nuclear translocator 2.	Uncharacterized protein.	0.928
ARNT2	AHRR	ENSPSIP00000011844	ENSPSIP00000007799	Aryl hydrocarbon receptor nuclear translocator 2.	Uncharacterized protein.	0.664
ARNT2	K7FI64_PELSI	ENSPSIP00000011844	ENSPSIP00000007724	Aryl hydrocarbon receptor nuclear translocator 2.	Uncharacterized protein.	0.664
ARNT2	K7GJN0_PELSI	ENSPSIP00000011844	ENSPSIP00000020491	Aryl hydrocarbon receptor nuclear translocator 2.	Uncharacterized protein.	0.893
CBFA2T2	CBFA2T3	ENSPSIP00000006751	ENSPSIP00000003666	CBFA2/RUNX1 partner transcriptional co-repressor 2.	Uncharacterized protein.	0.459
CBFA2T2	RUNX1T1	ENSPSIP00000006751	ENSPSIP00000002466	CBFA2/RUNX1 partner transcriptional co-repressor 2.	RUNX1 partner transcriptional co-repressor 1.	0.454
CBFA2T3	CBFA2T2	ENSPSIP00000003666	ENSPSIP00000006751	Uncharacterized protein.	CBFA2/RUNX1 partner transcriptional co-repressor 2.	0.459
CYP11A1	CYP19A1	ENSPSIP00000014954	ENSPSIP00000020111	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family.	0.401
CYP11A1	CYP26B1	ENSPSIP00000014954	ENSPSIP00000014920	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family.	0.570
CYP11A1	CYP26C1	ENSPSIP00000014954	ENSPSIP00000020108	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Cytochrome P450 family 26 subfamily C member 1; Belongs to the cytochrome P450 family.	0.491
CYP11A1	CYP46A1	ENSPSIP00000014954	ENSPSIP00000016212	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family.	0.463