18 items (Pelodiscus sinensis) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

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Others

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co-expression

protein homology

Your Input:
	UBC	Uncharacterized protein. (355 aa)
	SMAD3	Mothers against decapentaplegic homolog. (358 aa)
	UBA52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	RPS27A	Ubiquitin-like domain-containing protein. (140 aa)
	STUB1	STIP1 homology and U-box containing protein 1. (261 aa)
	K7FUJ5_PELSI	HECT domain-containing protein. (261 aa)
	SMURF2	E3 ubiquitin-protein ligase. (734 aa)
	LDLRAD4	Low density lipoprotein receptor class A domain containing 4. (212 aa)
	MTMR4	Myotubularin related protein 4. (1148 aa)
	STRAP	Serine/threonine kinase receptor associated protein. (323 aa)
	SMAD2	Mothers against decapentaplegic homolog. (496 aa)
	SMAD7	Mothers against decapentaplegic homolog. (387 aa)
	TGFBR2	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (584 aa)
	LOC102457599	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (567 aa)
	K7EXK2_PELSI	Ubiquitin-like domain-containing protein. (32 aa)
	PMEPA1	Prostate transmembrane protein, androgen induced 1. (150 aa)
	BAMBI	BMP and activin membrane bound inhibitor. (242 aa)
	TGFBR1	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)

Your Current Organism:

Pelodiscus sinensis

NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAMBI	LOC102457599	ENSPSIP00000019913	ENSPSIP00000003778	BMP and activin membrane bound inhibitor.	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...]	0.530
BAMBI	SMAD2	ENSPSIP00000019913	ENSPSIP00000007362	BMP and activin membrane bound inhibitor.	Mothers against decapentaplegic homolog.	0.486
BAMBI	SMAD3	ENSPSIP00000019913	ENSPSIP00000011835	BMP and activin membrane bound inhibitor.	Mothers against decapentaplegic homolog.	0.486
BAMBI	SMAD7	ENSPSIP00000019913	ENSPSIP00000006817	BMP and activin membrane bound inhibitor.	Mothers against decapentaplegic homolog.	0.810
BAMBI	TGFBR1	ENSPSIP00000019913	ENSPSIP00000020416	BMP and activin membrane bound inhibitor.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.760
BAMBI	TGFBR2	ENSPSIP00000019913	ENSPSIP00000005650	BMP and activin membrane bound inhibitor.	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...]	0.626
K7EXK2_PELSI	K7FUJ5_PELSI	ENSPSIP00000000512	ENSPSIP00000011705	Ubiquitin-like domain-containing protein.	HECT domain-containing protein.	0.667
K7EXK2_PELSI	RPS27A	ENSPSIP00000000512	ENSPSIP00000014184	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.988
K7EXK2_PELSI	SMURF2	ENSPSIP00000000512	ENSPSIP00000011487	Ubiquitin-like domain-containing protein.	E3 ubiquitin-protein ligase.	0.667
K7EXK2_PELSI	STUB1	ENSPSIP00000000512	ENSPSIP00000015567	Ubiquitin-like domain-containing protein.	STIP1 homology and U-box containing protein 1.	0.594
K7EXK2_PELSI	TGFBR2	ENSPSIP00000000512	ENSPSIP00000005650	Ubiquitin-like domain-containing protein.	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...]	0.448
K7EXK2_PELSI	UBC	ENSPSIP00000000512	ENSPSIP00000003340	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.949
K7FUJ5_PELSI	K7EXK2_PELSI	ENSPSIP00000011705	ENSPSIP00000000512	HECT domain-containing protein.	Ubiquitin-like domain-containing protein.	0.667
K7FUJ5_PELSI	LOC102457599	ENSPSIP00000011705	ENSPSIP00000003778	HECT domain-containing protein.	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...]	0.462
K7FUJ5_PELSI	RPS27A	ENSPSIP00000011705	ENSPSIP00000014184	HECT domain-containing protein.	Ubiquitin-like domain-containing protein.	0.892
K7FUJ5_PELSI	SMAD2	ENSPSIP00000011705	ENSPSIP00000007362	HECT domain-containing protein.	Mothers against decapentaplegic homolog.	0.770
K7FUJ5_PELSI	SMAD3	ENSPSIP00000011705	ENSPSIP00000011835	HECT domain-containing protein.	Mothers against decapentaplegic homolog.	0.770
K7FUJ5_PELSI	SMAD7	ENSPSIP00000011705	ENSPSIP00000006817	HECT domain-containing protein.	Mothers against decapentaplegic homolog.	0.961
K7FUJ5_PELSI	TGFBR1	ENSPSIP00000011705	ENSPSIP00000020416	HECT domain-containing protein.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.894
K7FUJ5_PELSI	TGFBR2	ENSPSIP00000011705	ENSPSIP00000005650	HECT domain-containing protein.	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...]	0.579