STRINGSTRING
LOC102445576 LOC102445576 LOC102452578 LOC102452578 LOC102453087 LOC102453087 LOC106732714 LOC106732714 K7EXK2_PELSI K7EXK2_PELSI JUN JUN K7EXN6_PELSI K7EXN6_PELSI LOC102454071 LOC102454071 LOC102445301 LOC102445301 LOC102454821 LOC102454821 H1-0 H1-0 LOC102455573 LOC102455573 LOC102455816 LOC102455816 LOC102443376 LOC102443376 LOC102444105 LOC102444105 ENSPSIP00000001420 ENSPSIP00000001420 LOC102446769 LOC102446769 LOC102448415 LOC102448415 LOC102448654 LOC102448654 ENSPSIP00000001542 ENSPSIP00000001542 LOC102450092 LOC102450092 LOC102450562 LOC102450562 LOC102450788 LOC102450788 LOC102451747 LOC102451747 LOC102451988 LOC102451988 K7F1M4_PELSI K7F1M4_PELSI BARHL2 BARHL2 CCNA1 CCNA1 MAPKAPK5 MAPKAPK5 CBX4 CBX4 CBX8 CBX8 CBX2 CBX2 CDK2 CDK2 RPS6KA2 RPS6KA2 LOC102454758 LOC102454758 UBC UBC MAPK1 MAPK1 ETS1 ETS1 FAM89B FAM89B MAPKAPK2 MAPKAPK2 BARX2 BARX2 K7F6V1_PELSI K7F6V1_PELSI K7F6V4_PELSI K7F6V4_PELSI MINK1 MINK1 K7F7E8_PELSI K7F7E8_PELSI LOC102449128 LOC102449128 NPTX2 NPTX2 FOSL2 FOSL2 NPTXR NPTXR HMGA1 HMGA1 ANAPC10 ANAPC10 MAPK10 MAPK10 ENSPSIP00000005926 ENSPSIP00000005926 EHMT1 EHMT1 FOSB FOSB H2AZ2 H2AZ2 MRE11 MRE11 K7FF44_PELSI K7FF44_PELSI CDKN2C CDKN2C ATM ATM MAPK7 MAPK7 BARHL1 BARHL1 MAPK14 MAPK14 CDC16 CDC16 TM7SF3 TM7SF3 NBN NBN RBBP4 RBBP4 ETS2 ETS2 CDC23 CDC23 EP400 EP400 TLX1 TLX1 CDKN1C CDKN1C SCMH1 SCMH1 ANAPC5 ANAPC5 H2AZ1 H2AZ1 CDC27 CDC27 DBX2 DBX2 CCNE2 CCNE2 CDK6 CDK6 RBBP7 RBBP7 NRK NRK CDKN1B CDKN1B K7FV74_PELSI K7FV74_PELSI RAD50 RAD50 EED EED K7FWJ1_PELSI K7FWJ1_PELSI TLX3 TLX3 UBA52 UBA52 MAP2K3 MAP2K3 KXD1 KXD1 ANAPC2 ANAPC2 TERF2 TERF2 FZR1 FZR1 ANAPC7 ANAPC7 DBX1 DBX1 SCML2 SCML2 CBX7 CBX7 CBX6 CBX6 ETV3 ETV3 RPS27A RPS27A ASF1A ASF1A ETV3L ETV3L CDK3 CDK3 RNF2 RNF2 ASF1B ASF1B TP53 TP53 SUZ12 SUZ12 PHC2 PHC2 K7G468_PELSI K7G468_PELSI MAP2K4 MAP2K4 HLX HLX CABIN1 CABIN1 MAPK11 MAPK11 K7G7G7_PELSI K7G7G7_PELSI ANAPC1 ANAPC1 ID4 ID4 PHC1 PHC1 UBN1 UBN1 EZH2 EZH2 UBE2S UBE2S CDKN2A CDKN2A K7GAN8_PELSI K7GAN8_PELSI MAPK9 MAPK9 ANAPC4 ANAPC4 MAPK8 MAPK8 MAPKAPK3 MAPKAPK3 CCNE1 CCNE1 CDK4 CDK4 CCNA2 CCNA2 CEBPB CEBPB MAP3K5 MAP3K5 LOC112543494 LOC112543494 MAP2K7 MAP2K7 MDM4 MDM4 K7GFM9_PELSI K7GFM9_PELSI NME8 NME8 MAP4K4 MAP4K4 EZH1 EZH1 MAP2K6 MAP2K6 ANAPC11 ANAPC11 FOS FOS ANAPC16 ANAPC16 TNIK TNIK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102445576H15 domain-containing protein. (217 aa)
LOC102452578Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC102453087Histone H2B 8. (126 aa)
LOC106732714Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (94 aa)
K7EXK2_PELSIUbiquitin-like domain-containing protein. (32 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (314 aa)
K7EXN6_PELSIHistone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
LOC102454071Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (109 aa)
LOC102445301Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
LOC102454821Histone H2B; Belongs to the histone H2B family. (126 aa)
H1-0H1 histone family member 0. (192 aa)
LOC102455573Histone H2B 8. (126 aa)
LOC102455816Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
LOC102443376H15 domain-containing protein. (173 aa)
LOC102444105Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSPSIP00000001420annotation not available (103 aa)
LOC102446769Histone H2B 8. (126 aa)
LOC102448415Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (107 aa)
LOC102448654Histone H4. (107 aa)
ENSPSIP00000001542annotation not available (103 aa)
LOC102450092Histone H4. (103 aa)
LOC102450562Histone H4. (103 aa)
LOC102450788Histone H4. (103 aa)
LOC102451747Histone H2B 1/2/3/4/6. (126 aa)
LOC102451988Histone H2B; Belongs to the histone H2B family. (126 aa)
K7F1M4_PELSIUncharacterized protein. (56 aa)
BARHL2BarH like homeobox 2. (364 aa)
CCNA1Cyclin A1; Belongs to the cyclin family. (416 aa)
MAPKAPK5Protein kinase domain-containing protein. (405 aa)
CBX4Chromobox 4. (456 aa)
CBX8Chromobox 8. (371 aa)
CBX2Chromobox 2. (504 aa)
CDK2Cyclin dependent kinase 2. (259 aa)
RPS6KA2Ribosomal protein S6 kinase. (734 aa)
LOC102454758Protein HIRA; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (1025 aa)
UBCUncharacterized protein. (355 aa)
MAPK1Mitogen-activated protein kinase. (322 aa)
ETS1ETS proto-oncogene 1, transcription factor. (485 aa)
FAM89BFamily with sequence similarity 89 member B. (179 aa)
MAPKAPK2MAPK activated protein kinase 2. (307 aa)
BARX2BARX homeobox 2. (269 aa)
K7F6V1_PELSIProtein kinase domain-containing protein. (832 aa)
K7F6V4_PELSIProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (442 aa)
MINK1CNH domain-containing protein. (290 aa)
K7F7E8_PELSIHistone H2B; Belongs to the histone H2B family. (134 aa)
LOC102449128Histone H2B; Belongs to the histone H2B family. (134 aa)
NPTX2Neuronal pentraxin 2. (443 aa)
FOSL2FOS like 2, AP-1 transcription factor subunit. (323 aa)
NPTXRNeuronal pentraxin receptor. (292 aa)
HMGA1High mobility group AT-hook 1. (108 aa)
ANAPC10Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa)
MAPK10Mitogen-activated protein kinase. (426 aa)
ENSPSIP00000005926annotation not available (72 aa)
EHMT1Euchromatic histone lysine methyltransferase 1. (1276 aa)
FOSBFosB proto-oncogene, AP-1 transcription factor subunit. (222 aa)
H2AZ2Histone H2A; Belongs to the histone H2A family. (128 aa)
MRE11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (714 aa)
K7FF44_PELSIUncharacterized protein. (2943 aa)
CDKN2CCyclin dependent kinase inhibitor 2C. (169 aa)
ATMNon-specific serine/threonine protein kinase. (3061 aa)
MAPK7Mitogen-activated protein kinase 7. (762 aa)
BARHL1BarH like homeobox 1. (321 aa)
MAPK14Mitogen-activated protein kinase. (321 aa)
CDC16Cell division cycle 16. (623 aa)
TM7SF3Transmembrane 7 superfamily member 3. (568 aa)
NBNNibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (778 aa)
RBBP4WD_REPEATS_REGION domain-containing protein. (390 aa)
ETS2ETS proto-oncogene 2, transcription factor. (485 aa)
CDC23Cell division cycle 23. (738 aa)
EP400E1A binding protein p400. (1504 aa)
TLX1T cell leukemia homeobox 1. (140 aa)
CDKN1CCyclin dependent kinase inhibitor 1C. (229 aa)
SCMH1Scm polycomb group protein homolog 1. (512 aa)
ANAPC5Anaphase promoting complex subunit 5. (703 aa)
H2AZ1Histone H2A; Belongs to the histone H2A family. (128 aa)
CDC27Cell division cycle 27. (834 aa)
DBX2Developing brain homeobox 2. (234 aa)
CCNE2Cyclin E2; Belongs to the cyclin family. (405 aa)
CDK6Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
RBBP7RB binding protein 7, chromatin remodeling factor. (391 aa)
NRKCNH domain-containing protein. (824 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
K7FV74_PELSIUncharacterized protein. (378 aa)
RAD50Zinc-hook domain-containing protein. (1304 aa)
EEDEmbryonic ectoderm development. (404 aa)
K7FWJ1_PELSIUBIQUITIN_CONJUGAT_2 domain-containing protein. (164 aa)
TLX3T cell leukemia homeobox 3. (291 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (337 aa)
KXD1KxDL motif containing 1. (176 aa)
ANAPC2Anaphase promoting complex subunit 2; Belongs to the cullin family. (771 aa)
TERF2Telomeric repeat binding factor 2. (654 aa)
FZR1Fizzy and cell division cycle 20 related 1. (495 aa)
ANAPC7Anaphase promoting complex subunit 7. (498 aa)
DBX1Developing brain homeobox 1. (348 aa)
SCML2Scm polycomb group protein like 2. (727 aa)
CBX7Chromobox 7. (247 aa)
CBX6Chromobox 6. (413 aa)
ETV3ETS variant 3. (530 aa)
RPS27AUbiquitin-like domain-containing protein. (140 aa)
ASF1AAnti-silencing function 1A histone chaperone. (205 aa)
ETV3LETS variant 3 like. (237 aa)
CDK3Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (304 aa)
RNF2Ring finger protein 2. (350 aa)
ASF1BAnti-silencing function 1B histone chaperone. (175 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (390 aa)
SUZ12SUZ12 polycomb repressive complex 2 subunit. (755 aa)
PHC2Polyhomeotic homolog 2. (846 aa)
K7G468_PELSIHira domain-containing protein. (523 aa)
MAP2K4Mitogen-activated protein kinase kinase 4. (328 aa)
HLXH2.0 like homeobox. (354 aa)
CABIN1Calcineurin binding protein 1. (2131 aa)
MAPK11Mitogen-activated protein kinase. (361 aa)
K7G7G7_PELSIUncharacterized protein. (720 aa)
ANAPC1Anaphase promoting complex subunit 1. (1341 aa)
ID4Inhibitor of DNA binding 4, HLH protein. (156 aa)
PHC1Polyhomeotic homolog 1. (996 aa)
UBN1Ubinuclein 1. (1017 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (764 aa)
UBE2SUbiquitin conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (114 aa)
CDKN2ACyclin dependent kinase inhibitor 2A. (139 aa)
K7GAN8_PELSIUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (107 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
ANAPC4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (800 aa)
MAPK8Mitogen-activated protein kinase. (429 aa)
MAPKAPK3MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (387 aa)
CCNE1Cyclin E1; Belongs to the cyclin family. (404 aa)
CDK4Cyclin dependent kinase 4. (216 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (362 aa)
CEBPBCCAAT enhancer binding protein beta. (315 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1218 aa)
LOC112543494Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (192 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (396 aa)
MDM4Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (473 aa)
K7GFM9_PELSIThioredoxin domain-containing protein. (86 aa)
NME8NME/NM23 family member 8; Belongs to the NDK family. (296 aa)
MAP4K4Mitogen-activated protein kinase kinase kinase kinase 4. (1293 aa)
EZH1Enhancer of zeste 1 polycomb repressive complex 2 subunit. (750 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
ANAPC11RING-type domain-containing protein. (84 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (374 aa)
ANAPC16Anaphase promoting complex subunit 16. (111 aa)
TNIKTRAF2 and NCK interacting kinase. (1324 aa)
Your Current Organism:
Pelodiscus sinensis
NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38
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