STRINGSTRING
CFTR CFTR EIF2S2 EIF2S2 PSMA2 PSMA2 PSMD4 PSMD4 LOC102455013 LOC102455013 K7GJ68_PELSI K7GJ68_PELSI LOC102443709 LOC102443709 ABCC1 ABCC1 PSMD3 PSMD3 ABCD2 ABCD2 PSME4 PSME4 KXD1 KXD1 UBA52 UBA52 PSMB2 PSMB2 ERLEC1 ERLEC1 ABCG8 ABCG8 PSMA4 PSMA4 ABCA5 ABCA5 DERL1 DERL1 ABCD3 ABCD3 ABCA3 ABCA3 K7FMD5_PELSI K7FMD5_PELSI LOC102461494 LOC102461494 PSMD10 PSMD10 PSMA6 PSMA6 K7FQ98_PELSI K7FQ98_PELSI K7FQI5_PELSI K7FQI5_PELSI PSMD7 PSMD7 PSMB3 PSMB3 PTCHD3 PTCHD3 ABCF1 ABCF1 ABCC10 ABCC10 ABCG5 ABCG5 VCP VCP K7FUW8_PELSI K7FUW8_PELSI PSMD1 PSMD1 K7F3C8_PELSI K7F3C8_PELSI PSMA8 PSMA8 ABCC9 ABCC9 ABCB10 ABCB10 PSMD6 PSMD6 UBC UBC PSMD11 PSMD11 PSMB6 PSMB6 PSMC3 PSMC3 PSMD14 PSMD14 SEL1L SEL1L PSMC5 PSMC5 PSMD8 PSMD8 PSMB7 PSMB7 PSMB4 PSMB4 PSMD5 PSMD5 PEX3 PEX3 ERLIN1 ERLIN1 PSMD12 PSMD12 DELE1 DELE1 SPATA5L1 SPATA5L1 PSMD13 PSMD13 K7F2E3_PELSI K7F2E3_PELSI K7F0N2_PELSI K7F0N2_PELSI KCNJ11 KCNJ11 K7EXK2_PELSI K7EXK2_PELSI PSMA5 PSMA5 ABCC12 ABCC12 PLEKHD1 PLEKHD1 ABCC3 ABCC3 SPATA5 SPATA5 DERL3 DERL3 RPS27A RPS27A RNF185 RNF185 PSMC6 PSMC6 ABCC5 ABCC5 SMPDL3A SMPDL3A ERLIN2 ERLIN2 PSMC2 PSMC2 LOC102459126 LOC102459126 PSMA1 PSMA1 SEL1L2 SEL1L2 ABCG4 ABCG4 EIF2S1 EIF2S1 PSMC1 PSMC1 PSMA3 PSMA3 PTCHD4 PTCHD4 PTCHD1 PTCHD1 LRP2BP LRP2BP ABCB7 ABCB7 ABCA13 ABCA13 ABCF3 ABCF3 ABCA12 ABCA12 EIF2S3 EIF2S3 PSMD9 PSMD9 PSMC4 PSMC4 PSMA7 PSMA7 ABCG1 ABCG1 LOC102451294 LOC102451294 PSMF1 PSMF1 K7GEK6_PELSI K7GEK6_PELSI K7GEL9_PELSI K7GEL9_PELSI SEL1L3 SEL1L3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1015 aa)
EIF2S2Eukaryotic translation initiation factor 2 subunit beta. (329 aa)
PSMA2Proteasome endopeptidase complex. (156 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (378 aa)
LOC102455013RING-type domain-containing protein. (193 aa)
K7GJ68_PELSIUncharacterized protein. (706 aa)
LOC102443709ABC transporter domain-containing protein. (336 aa)
ABCC1ATP binding cassette subfamily C member 1. (1531 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (461 aa)
ABCD2ATP binding cassette subfamily D member 2. (738 aa)
PSME4Proteasome activator subunit 4. (1837 aa)
KXD1KxDL motif containing 1. (176 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
PSMB2Proteasome subunit beta. (171 aa)
ERLEC1Endoplasmic reticulum lectin 1. (475 aa)
ABCG8ATP binding cassette subfamily G member 8. (677 aa)
PSMA4Proteasome subunit alpha type. (262 aa)
ABCA5ATP binding cassette subfamily A member 5. (1650 aa)
DERL1Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (250 aa)
ABCD3ATP binding cassette subfamily D member 3. (648 aa)
ABCA3ATP binding cassette subfamily A member 3. (1658 aa)
K7FMD5_PELSIUncharacterized protein. (701 aa)
LOC102461494Uncharacterized protein. (1633 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (190 aa)
PSMA6Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (246 aa)
K7FQ98_PELSIUncharacterized protein. (124 aa)
K7FQI5_PELSIABC transporter domain-containing protein. (648 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (323 aa)
PSMB3Proteasome subunit beta. (204 aa)
PTCHD3SSD domain-containing protein. (556 aa)
ABCF1ATP binding cassette subfamily F member 1. (289 aa)
ABCC10Uncharacterized protein. (1165 aa)
ABCG5ATP binding cassette subfamily G member 5. (606 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (763 aa)
K7FUW8_PELSIUncharacterized protein. (92 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (809 aa)
K7F3C8_PELSIProteasome subunit alpha type. (245 aa)
PSMA8Proteasome endopeptidase complex. (194 aa)
ABCC9ATP binding cassette subfamily C member 9. (1554 aa)
ABCB10ATP binding cassette subfamily B member 10. (567 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (371 aa)
UBCUncharacterized protein. (355 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (393 aa)
PSMB6Proteasome subunit beta 6. (228 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (426 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
SEL1LSEL1L adaptor subunit of ERAD E3 ubiquitin ligase. (791 aa)
PSMC5Proteasome 26S subunit, ATPase 5. (228 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (244 aa)
PSMB7Proteasome subunit beta. (277 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (230 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (453 aa)
PEX3Peroxisomal biogenesis factor 3. (351 aa)
ERLIN1ER lipid raft associated 1. (347 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (420 aa)
DELE1Uncharacterized protein. (525 aa)
SPATA5L1Spermatogenesis associated 5 like 1. (757 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (365 aa)
K7F2E3_PELSIUncharacterized protein. (944 aa)
K7F0N2_PELSIUncharacterized protein. (47 aa)
KCNJ11Potassium voltage-gated channel subfamily J member 11. (395 aa)
K7EXK2_PELSIUbiquitin-like domain-containing protein. (32 aa)
PSMA5Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (237 aa)
ABCC12ATP binding cassette subfamily C member 12. (1367 aa)
PLEKHD1Pleckstrin homology and coiled-coil domain containing D1. (503 aa)
ABCC3Uncharacterized protein. (1528 aa)
SPATA5Spermatogenesis associated 5. (829 aa)
DERL3Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (156 aa)
RPS27AUbiquitin-like domain-containing protein. (140 aa)
RNF185RING-type domain-containing protein. (193 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (288 aa)
ABCC5ATP binding cassette subfamily C member 5. (1435 aa)
SMPDL3ASphingomyelin phosphodiesterase acid like 3A. (420 aa)
ERLIN2ER lipid raft associated 2. (333 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (437 aa)
LOC102459126SSD domain-containing protein. (768 aa)
PSMA1Proteasome endopeptidase complex. (236 aa)
SEL1L2SEL1L2 adaptor subunit of ERAD E3 ligase. (594 aa)
ABCG4ATP binding cassette subfamily G member 4. (645 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit alpha. (315 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (439 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
PTCHD4Uncharacterized protein. (350 aa)
PTCHD1Patched domain containing 1. (488 aa)
LRP2BPLRP2 binding protein. (323 aa)
ABCB7ATP binding cassette subfamily B member 7. (673 aa)
ABCA13ATP binding cassette subfamily A member 13. (4753 aa)
ABCF3ATP binding cassette subfamily F member 3. (644 aa)
ABCA12ATP binding cassette subfamily A member 12. (2585 aa)
EIF2S3Tr-type G domain-containing protein. (450 aa)
PSMD9PDZ domain-containing protein. (166 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (406 aa)
PSMA7Proteasome endopeptidase complex. (220 aa)
ABCG1ATP binding cassette subfamily G member 1. (665 aa)
LOC102451294Uncharacterized protein. (809 aa)
PSMF1PI31_Prot_C domain-containing protein. (174 aa)
K7GEK6_PELSIUncharacterized protein. (158 aa)
K7GEL9_PELSIUncharacterized protein. (1361 aa)
SEL1L3Uncharacterized protein. (829 aa)
Your Current Organism:
Pelodiscus sinensis
NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38
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