STRINGSTRING
DUSP6 DUSP6 K7FL34_PELSI K7FL34_PELSI PPP4R1 PPP4R1 K7FK04_PELSI K7FK04_PELSI RELCH RELCH IRAK2 IRAK2 MAPK14 MAPK14 IL17D IL17D MAPK7 MAPK7 DUSP3 DUSP3 FOSB FOSB CREB1 CREB1 MAPK10 MAPK10 ATF7 ATF7 CREB5 CREB5 DUSP7 DUSP7 MAP3K20 MAP3K20 MAPK9 MAPK9 MAPK8 MAPK8 MAPKAPK3 MAPKAPK3 TAB2 TAB2 ATF1 ATF1 MAP2K7 MAP2K7 MAPK15 MAPK15 MAP2K6 MAP2K6 MAPK11 MAPK11 UBE2N UBE2N MAP2K4 MAP2K4 PPP2CA PPP2CA FOSL2 FOSL2 MAPKAPK2 MAPKAPK2 K7F6A0_PELSI K7F6A0_PELSI PPP2R1A PPP2R1A K7EXK2_PELSI K7EXK2_PELSI IL17RB IL17RB ATF2 ATF2 MAPK1 MAPK1 UBC UBC LOC102450501 LOC102450501 RPS6KA2 RPS6KA2 JUN JUN FNBP4 FNBP4 PPP2CB PPP2CB TAB3 TAB3 RPS27A RPS27A FOS FOS RPS6KA4 RPS6KA4 NOD1 NOD1 VRK3 VRK3 IKBKG IKBKG TAB1 TAB1 KXD1 KXD1 MAP2K3 MAP2K3 UBA52 UBA52 TRAF6 TRAF6 LOC102461321 LOC102461321 RIPK2 RIPK2 PPP4R4 PPP4R4 K7FQ52_PELSI K7FQ52_PELSI RPS6KA5 RPS6KA5 K7FN03_PELSI K7FN03_PELSI
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DUSP6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (382 aa)
K7FL34_PELSIUncharacterized protein. (170 aa)
PPP4R1Protein phosphatase 4 regulatory subunit 1. (945 aa)
K7FK04_PELSIUncharacterized protein. (171 aa)
RELCHRAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (724 aa)
IRAK2Interleukin 1 receptor associated kinase 2. (705 aa)
MAPK14Mitogen-activated protein kinase. (321 aa)
IL17DInterleukin 17D. (154 aa)
MAPK7Mitogen-activated protein kinase 7. (762 aa)
DUSP3Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (184 aa)
FOSBFosB proto-oncogene, AP-1 transcription factor subunit. (222 aa)
CREB1cAMP responsive element binding protein 1. (327 aa)
MAPK10Mitogen-activated protein kinase. (426 aa)
ATF7Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. (484 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (501 aa)
DUSP7Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (363 aa)
MAP3K20Uncharacterized protein. (796 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
MAPK8Mitogen-activated protein kinase. (429 aa)
MAPKAPK3MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (387 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (692 aa)
ATF1Activating transcription factor 1. (318 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (396 aa)
MAPK15Protein kinase domain-containing protein. (189 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
MAPK11Mitogen-activated protein kinase. (361 aa)
UBE2NUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
MAP2K4Mitogen-activated protein kinase kinase 4. (328 aa)
PPP2CASerine/threonine-protein phosphatase. (244 aa)
FOSL2FOS like 2, AP-1 transcription factor subunit. (323 aa)
MAPKAPK2MAPK activated protein kinase 2. (307 aa)
K7F6A0_PELSIUncharacterized protein. (163 aa)
PPP2R1AUncharacterized protein. (175 aa)
K7EXK2_PELSIUbiquitin-like domain-containing protein. (32 aa)
IL17RBInterleukin 17 receptor B. (481 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (492 aa)
MAPK1Mitogen-activated protein kinase. (322 aa)
UBCUncharacterized protein. (355 aa)
LOC102450501Uncharacterized protein. (357 aa)
RPS6KA2Ribosomal protein S6 kinase. (734 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (314 aa)
FNBP4Formin binding protein 4. (894 aa)
PPP2CBSerine/threonine-protein phosphatase. (307 aa)
TAB3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (706 aa)
RPS27AUbiquitin-like domain-containing protein. (140 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (374 aa)
RPS6KA4Ribosomal protein S6 kinase. (752 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (950 aa)
VRK3VRK serine/threonine kinase 3. (445 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (585 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (563 aa)
KXD1KxDL motif containing 1. (176 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (337 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (547 aa)
LOC102461321WRNPLPNID domain-containing protein. (929 aa)
RIPK2Receptor interacting serine/threonine kinase 2. (562 aa)
PPP4R4Protein phosphatase 4 regulatory subunit 4. (864 aa)
K7FQ52_PELSIProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (448 aa)
RPS6KA5Ribosomal protein S6 kinase. (833 aa)
K7FN03_PELSIProtein kinase domain-containing protein. (449 aa)
Your Current Organism:
Pelodiscus sinensis
NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38
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