STRINGSTRING
FADD FADD TRADD TRADD TLR4 TLR4 DAPK1 DAPK1 CASP3 CASP3 UNC5B UNC5B LOC102458875 LOC102458875 LOC102460485 LOC102460485 APPL2 APPL2 DAPK2 DAPK2 DCC DCC IGDCC4 IGDCC4 DAPK3 DAPK3 K7FVF1_PELSI K7FVF1_PELSI RIPK1 RIPK1 FASLG FASLG LOC102455743 LOC102455743 NEO1 NEO1 TNFSF11 TNFSF11 APPL1 APPL1 TNFSF10 TNFSF10 LOC102462633 LOC102462633 FAS FAS CASP9 CASP9 CFLAR CFLAR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FADDFas associated via death domain. (191 aa)
TRADDTNFRSF1A associated via death domain. (304 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (833 aa)
DAPK1Death associated protein kinase 1. (1430 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (286 aa)
UNC5BUnc-5 netrin receptor B. (944 aa)
LOC102458875Uncharacterized protein. (403 aa)
LOC102460485Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (404 aa)
APPL2Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (643 aa)
DAPK2Death associated protein kinase 2; Belongs to the protein kinase superfamily. (420 aa)
DCCUncharacterized protein. (415 aa)
IGDCC4Immunoglobulin superfamily DCC subclass member 4. (1126 aa)
DAPK3Death associated protein kinase 3; Belongs to the protein kinase superfamily. (456 aa)
K7FVF1_PELSIUncharacterized protein. (832 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (716 aa)
FASLGFas ligand. (245 aa)
LOC102455743Uncharacterized protein; Belongs to the peptidase C14A family. (237 aa)
NEO1Neogenin 1. (1432 aa)
TNFSF11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (245 aa)
APPL1Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (708 aa)
TNFSF10TNF superfamily member 10; Belongs to the tumor necrosis factor family. (309 aa)
LOC102462633Uncharacterized protein. (428 aa)
FASFas cell surface death receptor. (303 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (423 aa)
CFLARCASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (509 aa)
Your Current Organism:
Pelodiscus sinensis
NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.