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| | TP53BP2 | Tumor protein p53 binding protein 2. (1140 aa) |
| | FOXP4 | Forkhead box P4. (689 aa) |
| | L3MBTL1 | SAM domain-containing protein. (830 aa) |
| | ING1 | Inhibitor of growth protein. (281 aa) |
| | CCNA2 | Cyclin A2; Belongs to the cyclin family. (362 aa) |
| | DYRK2 | Dual specificity tyrosine phosphorylation regulated kinase 2. (598 aa) |
| | TP53INP2 | Tumor protein p53 inducible nuclear protein 2. (218 aa) |
| | TAF6 | TATA-box binding protein associated factor 6. (424 aa) |
| | MDM4 | Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (473 aa) |
| | RAD1 | RAD1 checkpoint DNA exonuclease. (281 aa) |
| | PRKAG2 | Protein kinase AMP-activated non-catalytic subunit gamma 2. (564 aa) |
| | KXD1 | KxDL motif containing 1. (176 aa) |
| | AIRE | Autoimmune regulator. (534 aa) |
| | UBA52 | Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa) |
| | PDPK1 | 3-phosphoinositide dependent protein kinase 1. (559 aa) |
| | TXNDC11 | Thioredoxin domain containing 11. (900 aa) |
| | EXD2 | Exonuclease 3'-5' domain containing 2. (621 aa) |
| | SSRP1 | FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (697 aa) |
| | PPP1R13B | Protein phosphatase 1 regulatory subunit 13B. (1093 aa) |
| | BLM | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (557 aa) |
| | K7FRX4_PELSI | Protein kinase domain-containing protein. (267 aa) |
| | L3MBTL3 | L3MBTL histone methyl-lysine binding protein 3. (814 aa) |
| | DYRK4 | Dual specificity tyrosine phosphorylation regulated kinase 4. (357 aa) |
| | TP53INP1 | Tumor protein p53 inducible nuclear protein 1. (236 aa) |
| | LOC102463045 | TAF4 domain-containing protein. (174 aa) |
| | USP7 | Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1106 aa) |
| | K7FQ62_PELSI | Uncharacterized protein. (809 aa) |
| | MEAF6 | MYST/Esa1 associated factor 6. (161 aa) |
| | NUAK2 | NUAK family kinase 2. (614 aa) |
| | RBBP8 | RB binding protein 8, endonuclease. (482 aa) |
| | RNF34 | Ring finger protein 34. (340 aa) |
| | TOPBP1 | DNA topoisomerase II binding protein 1. (1517 aa) |
| | ZNF385B | Zinc finger protein 385B. (520 aa) |
| | TAF10 | TATA-box binding protein associated factor 10. (124 aa) |
| | MLST8 | MTOR associated protein, LST8 homolog. (271 aa) |
| | LOC102461919 | SAM domain-containing protein. (668 aa) |
| | RFC3 | Replication factor C subunit 3. (304 aa) |
| | K7FKZ4_PELSI | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (386 aa) |
| | RBBP4 | WD_REPEATS_REGION domain-containing protein. (390 aa) |
| | JMY | Junction mediating and regulatory protein, p53 cofactor. (712 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | DNA2 | DNA replication helicase/nuclease 2. (714 aa) |
| | NBN | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (778 aa) |
| | ZNF385C | Zinc finger protein 385C. (412 aa) |
| | BRD1 | Bromodomain containing 1. (1186 aa) |
| | MTOR | Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2522 aa) |
| | TAF9 | TATA-box binding protein associated factor 9. (236 aa) |
| | BRPF3 | Bromodomain and PHD finger containing 3. (1028 aa) |
| | CSNK2B | Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (216 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (321 aa) |
| | GATAD2A | GATA zinc finger domain containing 2A. (596 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (603 aa) |
| | CDK1 | Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (303 aa) |
| | SUPT16H | SPT16 homolog, facilitates chromatin remodeling subunit. (515 aa) |
| | K7GAB9_PELSI | TAFH domain-containing protein. (848 aa) |
| | HIPK2 | Homeodomain interacting protein kinase 2. (1205 aa) |
| | BARD1 | BRCA1 associated RING domain 1. (691 aa) |
| | RAD17 | RAD17 checkpoint clamp loader component. (690 aa) |
| | ANKRD11 | ANK_REP_REGION domain-containing protein. (2723 aa) |
| | AURKA | Aurora kinase A; Belongs to the protein kinase superfamily. (409 aa) |
| | TAF2 | TATA-box binding protein associated factor 2. (1200 aa) |
| | RFFL | RING-type domain-containing protein. (362 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (361 aa) |
| | TDRD3 | Tudor domain containing 3. (651 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (560 aa) |
| | PIN1 | Peptidyl-prolyl cis-trans isomerase. (141 aa) |
| | MAPKAP1 | MAPK associated protein 1. (522 aa) |
| | BRPF1 | Uncharacterized protein. (698 aa) |
| | WRN | WRN RecQ like helicase. (1490 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (390 aa) |
| | TAF3 | TATA-box binding protein associated factor 3. (864 aa) |
| | PPP2CB | Serine/threonine-protein phosphatase. (307 aa) |
| | TBP | TATA-box binding protein. (299 aa) |
| | TAF4 | TATA-box binding protein associated factor 4. (1101 aa) |
| | RFC2 | Replication factor C subunit 2. (374 aa) |
| | HUS1 | Checkpoint protein; Belongs to the HUS1 family. (231 aa) |
| | K7FGU8_PELSI | PIPK domain-containing protein. (360 aa) |
| | K7G2C8_PELSI | POU domain protein. (289 aa) |
| | CDK3 | Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (304 aa) |
| | CHD3 | Chromodomain helicase DNA binding protein 3. (1112 aa) |
| | BRD7 | Bromodomain containing 7. (579 aa) |
| | K7FU23_PELSI | Uncharacterized protein. (111 aa) |
| | RICTOR | RPTOR independent companion of MTOR complex 2. (1715 aa) |
| | RBBP7 | RB binding protein 7, chromatin remodeling factor. (391 aa) |
| | K7FUU4_PELSI | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (191 aa) |
| | PIP4K2B | Phosphatidylinositol-5-phosphate 4-kinase type 2 beta. (364 aa) |
| | TBPL2 | TATA-box binding protein like 2. (330 aa) |
| | TTC5 | Tetratricopeptide repeat domain 5. (427 aa) |
| | RAD50 | Zinc-hook domain-containing protein. (1304 aa) |
| | K7G262_PELSI | ANK_REP_REGION domain-containing protein. (93 aa) |
| | MEIOB | Meiosis specific with OB-fold. (467 aa) |
| | RPS27A | Ubiquitin-like domain-containing protein. (140 aa) |
| | EXO1 | Exonuclease 1. (808 aa) |
| | HIPK3 | Homeodomain interacting protein kinase 3. (1193 aa) |
| | NOC2L | NOC2 like nucleolar associated transcriptional repressor. (657 aa) |
| | BANP | BTG3 associated nuclear protein. (508 aa) |
| | SLF1 | SMC5-SMC6 complex localization factor 1. (1062 aa) |
| | TP53RK | TP53 regulating kinase. (254 aa) |
| | CHD5 | Chromodomain helicase DNA binding protein 5. (1881 aa) |
| | AURKB | Aurora kinase B; Belongs to the protein kinase superfamily. (365 aa) |
| | ATM | Non-specific serine/threonine protein kinase. (3061 aa) |
| | ANKRD12 | Ankyrin repeat domain 12. (2060 aa) |
| | CCNG1 | Cyclin G1; Belongs to the cyclin family. (295 aa) |
| | MRE11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (714 aa) |
| | PIP4K2A | Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (358 aa) |
| | TAF12 | TATA-box binding protein associated factor 12. (161 aa) |
| | EHMT1 | Euchromatic histone lysine methyltransferase 1. (1276 aa) |
| | SMYD2 | SET and MYND domain containing 2. (421 aa) |
| | K7FC61_PELSI | BRCT_assoc domain-containing protein. (1048 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | TAF11 | TAFII28 domain-containing protein. (174 aa) |
| | TAF5 | TATA-box binding protein associated factor 5. (554 aa) |
| | PPP2CA | Serine/threonine-protein phosphatase. (244 aa) |
| | RFC5 | Replication factor C subunit 5. (319 aa) |
| | EP300 | E1A binding protein p300. (2399 aa) |
| | GATAD2B | GATA zinc finger domain containing 2B. (234 aa) |
| | RPA3 | Replication protein A3. (119 aa) |
| | CSNK2A2 | Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (340 aa) |
| | TP73 | Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (633 aa) |
| | BRD9 | Bromodomain containing 9. (447 aa) |
| | HIPK1 | Homeodomain interacting protein kinase 1. (1210 aa) |
| | TAF7 | TATA-box binding protein associated factor 7. (360 aa) |
| | TBPL1 | TATA-box binding protein like 1. (186 aa) |
| | PRKAA2 | Non-specific serine/threonine protein kinase. (520 aa) |
| | DYRK3 | Dual specificity tyrosine phosphorylation regulated kinase 3. (579 aa) |
| | K7F6A0_PELSI | Uncharacterized protein. (163 aa) |
| | PPP2R1A | Uncharacterized protein. (175 aa) |
| | RAD9B | Uncharacterized protein. (141 aa) |
| | UBC | Uncharacterized protein. (355 aa) |
| | RECQL4 | Uncharacterized protein. (847 aa) |
| | CDK2 | Cyclin dependent kinase 2. (259 aa) |
| | STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (373 aa) |
| | TAF1 | Transcription initiation factor TFIID subunit. (1824 aa) |
| | TAF5L | TATA-box binding protein associated factor 5 like. (585 aa) |
| | PRDM1 | PR/SET domain 1. (787 aa) |
| | TAF4B | TATA-box binding protein associated factor 4b. (724 aa) |
| | MAPKAPK5 | Protein kinase domain-containing protein. (405 aa) |
| | CCNA1 | Cyclin A1; Belongs to the cyclin family. (416 aa) |
| | PIP4P2 | Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (222 aa) |
| | TAF13 | TATA-box binding protein associated factor 13. (117 aa) |
| | RMI1 | RecQ mediated genome instability 1. (623 aa) |
| | POU4F2 | POU domain protein. (171 aa) |
| | K7F0N6_PELSI | SWIB domain-containing protein. (130 aa) |
| | ING2 | Inhibitor of growth family member 2. (173 aa) |
| | K7EYN7_PELSI | U1-type domain-containing protein. (92 aa) |
| | ANKRD31 | Uncharacterized protein. (300 aa) |
| | K7EXK2_PELSI | Ubiquitin-like domain-containing protein. (32 aa) |
| | K7EW96_PELSI | Uncharacterized protein. (63 aa) |
| | PIP4P1 | Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (109 aa) |
| | CDCA7 | Cell division cycle associated 7. (274 aa) |
| | TOP3A | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1038 aa) |
| | PHF20 | PHD finger protein 20. (1061 aa) |
| | PRKAB1 | Protein kinase AMP-activated non-catalytic subunit beta 1. (263 aa) |
| | RFC4 | Replication factor C subunit 4. (329 aa) |
| | CSNK2A1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa) |
| | ATR | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2661 aa) |
| | RAD9A | Cell cycle checkpoint control protein; Belongs to the rad9 family. (394 aa) |
| | K7GBZ7_PELSI | Uncharacterized protein. (1927 aa) |
| | ATRIP | ATR interacting protein. (519 aa) |
| | CHEK1 | Checkpoint kinase 1. (454 aa) |
| | NUAK1 | NUAK family kinase 1. (641 aa) |
| | TP63 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (470 aa) |
| | POU4F3 | POU domain protein. (337 aa) |
| | MDM2 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (465 aa) |
| | PRR5 | Proline rich 5. (404 aa) |
| | SETD9 | SET domain containing 9. (274 aa) |
