STRINGSTRING
SPRY2 SPRY2 FGFR3 FGFR3 SPRY3 SPRY3 K7EXK2_PELSI K7EXK2_PELSI FNDC3A FNDC3A MKNK1 MKNK1 UBC UBC PTPN11 PTPN11 PPP2CA PPP2CA LOC102447645 LOC102447645 K7FGG7_PELSI K7FGG7_PELSI FNDC3B FNDC3B FGF17 FGF17 FGF9 FGF9 FGF8 FGF8 FGF4 FGF4 GRB2 GRB2 FGF5 FGF5 FGF16 FGF16 FRS2 FRS2 MKNK2 MKNK2 FGF1 FGF1 LOC102443910 LOC102443910 PPP2CB PPP2CB RPS27A RPS27A K7FZH9_PELSI K7FZH9_PELSI FGF2 FGF2 FGF18 FGF18 BRAF BRAF FGF23 FGF23 UBA52 UBA52 FGF20 FGF20
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SPRY2Sprouty RTK signaling antagonist 2. (313 aa)
FGFR3Fibroblast growth factor receptor. (827 aa)
SPRY3Sprouty RTK signaling antagonist 3. (290 aa)
K7EXK2_PELSIUbiquitin-like domain-containing protein. (32 aa)
FNDC3AFibronectin type III domain containing 3A. (1142 aa)
MKNK1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (471 aa)
UBCUncharacterized protein. (355 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (591 aa)
PPP2CASerine/threonine-protein phosphatase. (244 aa)
LOC102447645Uncharacterized protein. (227 aa)
K7FGG7_PELSIUncharacterized protein. (738 aa)
FNDC3BFibronectin type III domain containing 3B. (1211 aa)
FGF17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (228 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (192 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
FGF5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (251 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)
MKNK2MAPK interacting serine/threonine kinase 2; Belongs to the protein kinase superfamily. (467 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
LOC102443910Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
PPP2CBSerine/threonine-protein phosphatase. (307 aa)
RPS27AUbiquitin-like domain-containing protein. (140 aa)
K7FZH9_PELSIUncharacterized protein. (310 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (97 aa)
FGF18Fibroblast growth factor 18; Belongs to the heparin-binding growth factors family. (204 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (760 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (250 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (215 aa)
Your Current Organism:
Pelodiscus sinensis
NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38
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