46 items (Pelodiscus sinensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	UBE2N	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
	K7EXK2_PELSI	Ubiquitin-like domain-containing protein. (32 aa)
	USP45	Ubiquitin carboxyl-terminal hydrolase. (823 aa)
	GTF2H1	General transcription factor IIH subunit 1. (548 aa)
	UBC	Uncharacterized protein. (355 aa)
	RPA3	Replication protein A3. (119 aa)
	RBX1	Ring-box 1. (120 aa)
	DDB2	Damage specific DNA binding protein 2. (508 aa)
	PIAS3	Protein inhibitor of activated STAT 3. (602 aa)
	KCTD2	Potassium channel tetramerization domain containing 2. (257 aa)
	SUMO4	Small ubiquitin-related modifier. (95 aa)
	GTF2H4	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (438 aa)
	BIVM	Uncharacterized protein. (1604 aa)
	RNF111	Ring finger protein 111. (984 aa)
	GTF2H3	General transcription factor IIH subunit 3. (330 aa)
	GTF2H5	General transcription factor IIH subunit 5. (71 aa)
	CUL4B	Cullin 4B; Belongs to the cullin family. (913 aa)
	PARP1	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (975 aa)
	SUMO3	Small ubiquitin-related modifier. (88 aa)
	VTCN1	IGv domain-containing protein. (151 aa)
	RPA1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (603 aa)
	VWA5B2	Von Willebrand factor A domain containing 5B2. (1274 aa)
	XPC	XPC complex subunit, DNA damage recognition and repair factor. (949 aa)
	RAD23B	RAD23 homolog B, nucleotide excision repair protein. (392 aa)
	UBE2V2	Ubiquitin conjugating enzyme E2 V2. (144 aa)
	ERCC3	ERCC excision repair 3, TFIIH core complex helicase subunit. (717 aa)
	GTF2H2	General transcription factor IIH subunit. (395 aa)
	MNAT1	CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
	CUL4A	CULLIN_2 domain-containing protein; Belongs to the cullin family. (571 aa)
	K7G6G0_PELSI	CULLIN_2 domain-containing protein; Belongs to the cullin family. (189 aa)
	DDB1	Damage specific DNA binding protein 1. (1124 aa)
	RAD23A	RAD23 homolog A, nucleotide excision repair protein. (348 aa)
	CCNH	Cyclin H; Belongs to the cyclin family. (363 aa)
	MEIOB	Meiosis specific with OB-fold. (467 aa)
	CHD1L	Chromodomain helicase DNA binding protein 1 like. (917 aa)
	RPS27A	Ubiquitin-like domain-containing protein. (140 aa)
	PIAS1	Protein inhibitor of activated STAT 1. (641 aa)
	CETN3	Centrin 3. (167 aa)
	SUMO1	Small ubiquitin-related modifier. (101 aa)
	KXD1	KxDL motif containing 1. (176 aa)
	UBA52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	UBE2I	Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. (162 aa)
	ERCC1	ERCC excision repair 1, endonuclease non-catalytic subunit. (275 aa)
	CDK7	Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (343 aa)
	WDR76	WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family. (598 aa)
	XPA	XPA, DNA damage recognition and repair factor. (226 aa)

Your Current Organism:

Pelodiscus sinensis

NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BIVM	CCNH	ENSPSIP00000020602	ENSPSIP00000014573	Uncharacterized protein.	Cyclin H; Belongs to the cyclin family.	0.596
BIVM	CDK7	ENSPSIP00000020602	ENSPSIP00000011233	Uncharacterized protein.	Cyclin dependent kinase 7; Belongs to the protein kinase superfamily.	0.551
BIVM	CETN3	ENSPSIP00000020602	ENSPSIP00000013269	Uncharacterized protein.	Centrin 3.	0.476
BIVM	CHD1L	ENSPSIP00000020602	ENSPSIP00000014235	Uncharacterized protein.	Chromodomain helicase DNA binding protein 1 like.	0.697
BIVM	CUL4A	ENSPSIP00000020602	ENSPSIP00000015877	Uncharacterized protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.537
BIVM	CUL4B	ENSPSIP00000020602	ENSPSIP00000019008	Uncharacterized protein.	Cullin 4B; Belongs to the cullin family.	0.537
BIVM	DDB1	ENSPSIP00000020602	ENSPSIP00000015016	Uncharacterized protein.	Damage specific DNA binding protein 1.	0.787
BIVM	DDB2	ENSPSIP00000020602	ENSPSIP00000010113	Uncharacterized protein.	Damage specific DNA binding protein 2.	0.733
BIVM	ERCC1	ENSPSIP00000020602	ENSPSIP00000011840	Uncharacterized protein.	ERCC excision repair 1, endonuclease non-catalytic subunit.	0.898
BIVM	ERCC3	ENSPSIP00000020602	ENSPSIP00000016662	Uncharacterized protein.	ERCC excision repair 3, TFIIH core complex helicase subunit.	0.976
BIVM	GTF2H1	ENSPSIP00000020602	ENSPSIP00000002659	Uncharacterized protein.	General transcription factor IIH subunit 1.	0.992
BIVM	GTF2H2	ENSPSIP00000020602	ENSPSIP00000016598	Uncharacterized protein.	General transcription factor IIH subunit.	0.911
BIVM	GTF2H3	ENSPSIP00000020602	ENSPSIP00000019683	Uncharacterized protein.	General transcription factor IIH subunit 3.	0.704
BIVM	GTF2H4	ENSPSIP00000020602	ENSPSIP00000007277	Uncharacterized protein.	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.683
BIVM	GTF2H5	ENSPSIP00000020602	ENSPSIP00000019607	Uncharacterized protein.	General transcription factor IIH subunit 5.	0.739
BIVM	K7EXK2_PELSI	ENSPSIP00000020602	ENSPSIP00000000512	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.419
BIVM	K7G6G0_PELSI	ENSPSIP00000020602	ENSPSIP00000015871	Uncharacterized protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.537
BIVM	MEIOB	ENSPSIP00000020602	ENSPSIP00000014291	Uncharacterized protein.	Meiosis specific with OB-fold.	0.701
BIVM	PARP1	ENSPSIP00000020602	ENSPSIP00000018712	Uncharacterized protein.	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	0.670
BIVM	RAD23A	ENSPSIP00000020602	ENSPSIP00000014873	Uncharacterized protein.	RAD23 homolog A, nucleotide excision repair protein.	0.698