STRINGSTRING
PSMD10 PSMD10 PSMA6 PSMA6 ANAPC5 ANAPC5 H2AZ1 H2AZ1 CDC27 CDC27 KPNA6 KPNA6 PSMD7 PSMD7 PSMB3 PSMB3 POLA1 POLA1 KPNB1 KPNB1 MCM7 MCM7 MCM6 MCM6 LOC102463705 LOC102463705 PSMD3 PSMD3 PSMB2 PSMB2 MCM2 MCM2 PSMC1 PSMC1 PSMA3 PSMA3 ANAPC1 ANAPC1 UBE2S UBE2S POLE3 POLE3 K7GAN8_PELSI K7GAN8_PELSI PRIM2 PRIM2 MCM8 MCM8 PSMD4 PSMD4 PSMA2 PSMA2 ANAPC16 ANAPC16 ANAPC11 ANAPC11 KPNA1 KPNA1 PSMF1 PSMF1 PSMD2 PSMD2 PSMC4 PSMC4 POLE POLE MCM10 MCM10 ANAPC4 ANAPC4 PSMD9 PSMD9 CDK2 CDK2 CDC45 CDC45 PSMD6 PSMD6 CDC7 CDC7 K7F3C8_PELSI K7F3C8_PELSI CDC6 CDC6 PSMD1 PSMD1 LOC102451988 LOC102451988 LOC102451747 LOC102451747 LOC102450788 LOC102450788 LOC102450562 LOC102450562 LOC102450092 LOC102450092 ENSPSIP00000001542 ENSPSIP00000001542 LOC102448654 LOC102448654 LOC102448415 LOC102448415 LOC102446769 LOC102446769 ENSPSIP00000001420 ENSPSIP00000001420 LOC102444105 LOC102444105 LOC102455816 LOC102455816 LOC102455573 LOC102455573 LOC102454821 LOC102454821 LOC102445301 LOC102445301 LOC102454071 LOC102454071 K7EXN6_PELSI K7EXN6_PELSI K7EXK2_PELSI K7EXK2_PELSI LOC102453087 LOC102453087 LOC106732714 LOC106732714 LOC102452578 LOC102452578 RPA1 RPA1 K7FWJ1_PELSI K7FWJ1_PELSI UBA52 UBA52 KXD1 KXD1 ANAPC2 ANAPC2 PSMB1 PSMB1 ORC3 ORC3 PSMA5 PSMA5 FZR1 FZR1 ANAPC7 ANAPC7 MCM9 MCM9 RPS27A RPS27A MEIOB MEIOB CDK3 CDK3 PSMC6 PSMC6 PSMC2 PSMC2 LOC102462305 LOC102462305 PSMA1 PSMA1 K7G5T8_PELSI K7G5T8_PELSI ORC6 ORC6 CDT1 CDT1 UBC UBC PSMD11 PSMD11 K7F650_PELSI K7F650_PELSI PSMB6 PSMB6 FAM89B FAM89B K7F7E8_PELSI K7F7E8_PELSI LOC102449128 LOC102449128 ORC5 ORC5 PSMC3 PSMC3 ORC2 ORC2 PSMD14 PSMD14 RPA3 RPA3 PSMC5 PSMC5 ANAPC10 ANAPC10 GMNN GMNN PSMD8 PSMD8 PSMB7 PSMB7 PSMB4 PSMB4 H2AZ2 H2AZ2 PSMD5 PSMD5 PSMD12 PSMD12 DBF4 DBF4 MCM3 MCM3 ORC4 ORC4 PSMD13 PSMD13 CDC16 CDC16 TM7SF3 TM7SF3 PSMA4 PSMA4 POLE2 POLE2 KPNA5 KPNA5 CDC23 CDC23 MCM5 MCM5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PSMD10Proteasome 26S subunit, non-ATPase 10. (190 aa)
PSMA6Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (246 aa)
ANAPC5Anaphase promoting complex subunit 5. (703 aa)
H2AZ1Histone H2A; Belongs to the histone H2A family. (128 aa)
CDC27Cell division cycle 27. (834 aa)
KPNA6Importin subunit alpha; Belongs to the importin alpha family. (575 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (323 aa)
PSMB3Proteasome subunit beta. (204 aa)
POLA1DNA polymerase. (1351 aa)
KPNB1Karyopherin subunit beta 1. (843 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (615 aa)
MCM6DNA helicase; Belongs to the MCM family. (811 aa)
LOC102463705Uncharacterized protein. (526 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (461 aa)
PSMB2Proteasome subunit beta. (171 aa)
MCM2DNA helicase; Belongs to the MCM family. (826 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (439 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
ANAPC1Anaphase promoting complex subunit 1. (1341 aa)
UBE2SUbiquitin conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (114 aa)
POLE3CBFD_NFYB_HMF domain-containing protein. (141 aa)
K7GAN8_PELSIUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (107 aa)
PRIM2DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (545 aa)
MCM8MCM domain-containing protein; Belongs to the MCM family. (825 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (378 aa)
PSMA2Proteasome endopeptidase complex. (156 aa)
ANAPC16Anaphase promoting complex subunit 16. (111 aa)
ANAPC11RING-type domain-containing protein. (84 aa)
KPNA1Importin subunit alpha; Belongs to the importin alpha family. (538 aa)
PSMF1PI31_Prot_C domain-containing protein. (174 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (911 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (406 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2166 aa)
MCM10Minichromosome maintenance 10 replication initiation factor. (865 aa)
ANAPC4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (800 aa)
PSMD9PDZ domain-containing protein. (166 aa)
CDK2Cyclin dependent kinase 2. (259 aa)
CDC45Cell division cycle 45. (596 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (371 aa)
CDC7Cell division cycle 7. (569 aa)
K7F3C8_PELSIProteasome subunit alpha type. (245 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (548 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (809 aa)
LOC102451988Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC102451747Histone H2B 1/2/3/4/6. (126 aa)
LOC102450788Histone H4. (103 aa)
LOC102450562Histone H4. (103 aa)
LOC102450092Histone H4. (103 aa)
ENSPSIP00000001542annotation not available (103 aa)
LOC102448654Histone H4. (107 aa)
LOC102448415Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (107 aa)
LOC102446769Histone H2B 8. (126 aa)
ENSPSIP00000001420annotation not available (103 aa)
LOC102444105Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC102455816Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
LOC102455573Histone H2B 8. (126 aa)
LOC102454821Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC102445301Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
LOC102454071Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (109 aa)
K7EXN6_PELSIHistone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
K7EXK2_PELSIUbiquitin-like domain-containing protein. (32 aa)
LOC102453087Histone H2B 8. (126 aa)
LOC106732714Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (94 aa)
LOC102452578Histone H2B; Belongs to the histone H2B family. (126 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (603 aa)
K7FWJ1_PELSIUBIQUITIN_CONJUGAT_2 domain-containing protein. (164 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
KXD1KxDL motif containing 1. (176 aa)
ANAPC2Anaphase promoting complex subunit 2; Belongs to the cullin family. (771 aa)
PSMB1Proteasome subunit beta. (240 aa)
ORC3Origin recognition complex subunit 3. (724 aa)
PSMA5Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (237 aa)
FZR1Fizzy and cell division cycle 20 related 1. (495 aa)
ANAPC7Anaphase promoting complex subunit 7. (498 aa)
MCM9Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1183 aa)
RPS27AUbiquitin-like domain-containing protein. (140 aa)
MEIOBMeiosis specific with OB-fold. (467 aa)
CDK3Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (304 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (288 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (437 aa)
LOC102462305DNA helicase; Belongs to the MCM family. (812 aa)
PSMA1Proteasome endopeptidase complex. (236 aa)
K7G5T8_PELSIDNA helicase; Belongs to the MCM family. (840 aa)
ORC6Origin recognition complex subunit 6. (272 aa)
CDT1Chromatin licensing and DNA replication factor 1. (689 aa)
UBCUncharacterized protein. (355 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (393 aa)
K7F650_PELSIDNA primase; Belongs to the eukaryotic-type primase small subunit family. (382 aa)
PSMB6Proteasome subunit beta 6. (228 aa)
FAM89BFamily with sequence similarity 89 member B. (179 aa)
K7F7E8_PELSIHistone H2B; Belongs to the histone H2B family. (134 aa)
LOC102449128Histone H2B; Belongs to the histone H2B family. (134 aa)
ORC5Origin recognition complex subunit 5. (447 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (426 aa)
ORC2Origin recognition complex subunit 2. (585 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
RPA3Replication protein A3. (119 aa)
PSMC5Proteasome 26S subunit, ATPase 5. (228 aa)
ANAPC10Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa)
GMNNGeminin DNA replication inhibitor. (223 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (244 aa)
PSMB7Proteasome subunit beta. (277 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (230 aa)
H2AZ2Histone H2A; Belongs to the histone H2A family. (128 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (453 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (420 aa)
DBF4DBF4 zinc finger. (675 aa)
MCM3DNA helicase; Belongs to the MCM family. (788 aa)
ORC4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (436 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (365 aa)
CDC16Cell division cycle 16. (623 aa)
TM7SF3Transmembrane 7 superfamily member 3. (568 aa)
PSMA4Proteasome subunit alpha type. (262 aa)
POLE2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa)
KPNA5Karyopherin subunit alpha 5. (604 aa)
CDC23Cell division cycle 23. (738 aa)
MCM5DNA helicase; Belongs to the MCM family. (734 aa)
Your Current Organism:
Pelodiscus sinensis
NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38
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