STRINGSTRING
LRRC34 LRRC34 RPS6KA4 RPS6KA4 SARM1 SARM1 FOS FOS MAP2K6 MAP2K6 MAPK15 MAPK15 MAP2K7 MAP2K7 ATF1 ATF1 VWC2 VWC2 TAB2 TAB2 MAPKAPK3 MAPKAPK3 MAPK8 MAPK8 MAPK9 MAPK9 MAP3K20 MAP3K20 TRAF3 TRAF3 VWC2L VWC2L NLRX1 NLRX1 UBE2D1 UBE2D1 LRRC45 LRRC45 MAP2K4 MAP2K4 FNBP4 FNBP4 PPP2CB PPP2CB BIRC7 BIRC7 TAB3 TAB3 RPS27A RPS27A K7FZH9_PELSI K7FZH9_PELSI NOD1 NOD1 VRK3 VRK3 IKBKG IKBKG N4BP1 N4BP1 TAB1 TAB1 KXD1 KXD1 K7FWX0_PELSI K7FWX0_PELSI K7FWT7_PELSI K7FWT7_PELSI MAP2K3 MAP2K3 UBA52 UBA52 K7FW92_PELSI K7FW92_PELSI LOC102453021 LOC102453021 TRAF6 TRAF6 K7FVS3_PELSI K7FVS3_PELSI S100B S100B RIPK1 RIPK1 LOC102448753 LOC102448753 LOC102461321 LOC102461321 RIPK2 RIPK2 NFKBIA NFKBIA LRRC74B LRRC74B PPP4R4 PPP4R4 TRAF5 TRAF5 K7FQ52_PELSI K7FQ52_PELSI NFKB1 NFKB1 RPS6KA5 RPS6KA5 NKIRAS1 NKIRAS1 K7FN03_PELSI K7FN03_PELSI DUSP6 DUSP6 USP14 USP14 PPP4R1 PPP4R1 RELCH RELCH NKIRAS2 NKIRAS2 UBE2D3 UBE2D3 IRAK2 IRAK2 TBK1 TBK1 MAPK14 MAPK14 MAPK7 MAPK7 DUSP3 DUSP3 K7FF63_PELSI K7FF63_PELSI CHUK CHUK K7FER2_PELSI K7FER2_PELSI FOSB FOSB CREB1 CREB1 IKBKB IKBKB MAPK10 MAPK10 LOC102447645 LOC102447645 ATF7 ATF7 UBE2N UBE2N PPP2CA PPP2CA FADD FADD TANK TANK FOSL2 FOSL2 TLR4 TLR4 MAPKAPK2 MAPKAPK2 IKBKE IKBKE PTPN11 PTPN11 K7F6A0_PELSI K7F6A0_PELSI PPP2R1A PPP2R1A ATF2 ATF2 MAPK1 MAPK1 UBC UBC LRRC14 LRRC14 LOC102450501 LOC102450501 RPS6KA2 RPS6KA2 NFKBIB NFKBIB NLRC5 NLRC5 K7EZT1_PELSI K7EZT1_PELSI K7EZL8_PELSI K7EZL8_PELSI JUN JUN K7EXK2_PELSI K7EXK2_PELSI LRRC74A LRRC74A USP18 USP18 DUSP7 DUSP7 CREB5 CREB5 LOC102443910 LOC102443910 LRRC71 LRRC71 MAPK11 MAPK11 LRRC31 LRRC31
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LRRC34Leucine rich repeat containing 34. (411 aa)
RPS6KA4Ribosomal protein S6 kinase. (752 aa)
SARM1Sterile alpha and TIR motif containing 1. (712 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (374 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
MAPK15Protein kinase domain-containing protein. (189 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (396 aa)
ATF1Activating transcription factor 1. (318 aa)
VWC2Von Willebrand factor C domain containing 2. (331 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (692 aa)
MAPKAPK3MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (387 aa)
MAPK8Mitogen-activated protein kinase. (429 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
MAP3K20Uncharacterized protein. (796 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (566 aa)
VWC2LVon Willebrand factor C domain containing 2 like. (222 aa)
NLRX1NLR family member X1. (990 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (110 aa)
LRRC45Leucine rich repeat containing 45. (674 aa)
MAP2K4Mitogen-activated protein kinase kinase 4. (328 aa)
FNBP4Formin binding protein 4. (894 aa)
PPP2CBSerine/threonine-protein phosphatase. (307 aa)
BIRC7Baculoviral IAP repeat containing 7. (352 aa)
TAB3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (706 aa)
RPS27AUbiquitin-like domain-containing protein. (140 aa)
K7FZH9_PELSIUncharacterized protein. (310 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (950 aa)
VRK3VRK serine/threonine kinase 3. (445 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (585 aa)
N4BP1NEDD4 binding protein 1. (836 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (563 aa)
KXD1KxDL motif containing 1. (176 aa)
K7FWX0_PELSIRNase_Zc3h12a domain-containing protein. (658 aa)
K7FWT7_PELSIProtein kinase domain-containing protein. (174 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (337 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
K7FW92_PELSIUncharacterized protein. (222 aa)
LOC102453021Uncharacterized protein. (886 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (547 aa)
K7FVS3_PELSIUncharacterized protein. (1102 aa)
S100BS100 calcium binding protein B; Belongs to the S-100 family. (92 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (716 aa)
LOC102448753Uncharacterized protein. (611 aa)
LOC102461321WRNPLPNID domain-containing protein. (929 aa)
RIPK2Receptor interacting serine/threonine kinase 2. (562 aa)
NFKBIAANK_REP_REGION domain-containing protein. (238 aa)
LRRC74BUncharacterized protein. (341 aa)
PPP4R4Protein phosphatase 4 regulatory subunit 4. (864 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (567 aa)
K7FQ52_PELSIProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (448 aa)
NFKB1Nuclear factor kappa B subunit 1. (993 aa)
RPS6KA5Ribosomal protein S6 kinase. (833 aa)
NKIRAS1NFKB inhibitor interacting Ras like 1. (191 aa)
K7FN03_PELSIProtein kinase domain-containing protein. (449 aa)
DUSP6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (382 aa)
USP14Ubiquitin carboxyl-terminal hydrolase. (480 aa)
PPP4R1Protein phosphatase 4 regulatory subunit 1. (945 aa)
RELCHRAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (724 aa)
NKIRAS2NFKB inhibitor interacting Ras like 2. (191 aa)
UBE2D3Ubiquitin conjugating enzyme E2 D3; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
IRAK2Interleukin 1 receptor associated kinase 2. (705 aa)
TBK1TANK binding kinase 1. (728 aa)
MAPK14Mitogen-activated protein kinase. (321 aa)
MAPK7Mitogen-activated protein kinase 7. (762 aa)
DUSP3Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (184 aa)
K7FF63_PELSIUncharacterized protein. (837 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (716 aa)
K7FER2_PELSIUncharacterized protein. (478 aa)
FOSBFosB proto-oncogene, AP-1 transcription factor subunit. (222 aa)
CREB1cAMP responsive element binding protein 1. (327 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (714 aa)
MAPK10Mitogen-activated protein kinase. (426 aa)
LOC102447645Uncharacterized protein. (227 aa)
ATF7Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. (484 aa)
UBE2NUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
PPP2CASerine/threonine-protein phosphatase. (244 aa)
FADDFas associated via death domain. (191 aa)
TANKTRAF family member associated NFKB activator. (427 aa)
FOSL2FOS like 2, AP-1 transcription factor subunit. (323 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (833 aa)
MAPKAPK2MAPK activated protein kinase 2. (307 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (728 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (591 aa)
K7F6A0_PELSIUncharacterized protein. (163 aa)
PPP2R1AUncharacterized protein. (175 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (492 aa)
MAPK1Mitogen-activated protein kinase. (322 aa)
UBCUncharacterized protein. (355 aa)
LRRC14Uncharacterized protein. (556 aa)
LOC102450501Uncharacterized protein. (357 aa)
RPS6KA2Ribosomal protein S6 kinase. (734 aa)
NFKBIBNFKB inhibitor beta. (275 aa)
NLRC5NACHT domain-containing protein. (482 aa)
K7EZT1_PELSIUncharacterized protein. (496 aa)
K7EZL8_PELSIUncharacterized protein. (250 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (314 aa)
K7EXK2_PELSIUbiquitin-like domain-containing protein. (32 aa)
LRRC74ALeucine rich repeat containing 74A. (450 aa)
USP18USP domain-containing protein; Belongs to the peptidase C19 family. (364 aa)
DUSP7Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (363 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (501 aa)
LOC102443910Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
LRRC71Leucine rich repeat containing 71. (261 aa)
MAPK11Mitogen-activated protein kinase. (361 aa)
LRRC31Leucine rich repeat containing 31. (557 aa)
Your Current Organism:
Pelodiscus sinensis
NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38
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