STRINGSTRING
JUN JUN CITED2 CITED2 PGAM5 PGAM5 ATG5 ATG5 UBC UBC BCL2L1 BCL2L1 RAB7B RAB7B NRAS NRAS CSNK2A2 CSNK2A2 BECN1 BECN1 USP15 USP15 PINK1 PINK1 MAPK10 MAPK10 NBR1 NBR1 PRKN PRKN CALCOCO2 CALCOCO2 USP30 USP30 AMBRA1 AMBRA1 CSNK2B CSNK2B FIS1 FIS1 TBK1 TBK1 FOXO3 FOXO3 K7FKZ4_PELSI K7FKZ4_PELSI GABARAPL1 GABARAPL1 ULK1 ULK1 MRAS MRAS HIF1A HIF1A MFN2 MFN2 ATF4 ATF4 UBA52 UBA52 RAB7A RAB7A TBC1D15 TBC1D15 MITF MITF RPS27A RPS27A SRC SRC BCL2L13 BCL2L13 TP53 TP53 MFN1 MFN1 FUNDC1 FUNDC1 K7G5M9_PELSI K7G5M9_PELSI RHOT2 RHOT2 TAX1BP1 TAX1BP1 HRAS HRAS LOC102450218 LOC102450218 KRAS KRAS RRAS2 RRAS2 MAPK9 MAPK9 OPTN OPTN MAPK8 MAPK8 BNIP3 BNIP3 BNIP3L BNIP3L CSNK2A1 CSNK2A1 USP8 USP8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (314 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (231 aa)
PGAM5PGAM family member 5, mitochondrial serine/threonine protein phosphatase. (226 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (276 aa)
UBCUncharacterized protein. (355 aa)
BCL2L1BCL2 like 1. (229 aa)
RAB7BRAB7B, member RAS oncogene family. (200 aa)
NRASNRAS proto-oncogene, GTPase. (123 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (340 aa)
BECN1Uncharacterized protein. (407 aa)
USP15Ubiquitin carboxyl-terminal hydrolase. (984 aa)
PINK1PTEN induced kinase 1. (364 aa)
MAPK10Mitogen-activated protein kinase. (426 aa)
NBR1NBR1 autophagy cargo receptor. (995 aa)
PRKNRBR-type E3 ubiquitin transferase. (119 aa)
CALCOCO2Calcium binding and coiled-coil domain 2. (454 aa)
USP30Ubiquitin carboxyl-terminal hydrolase. (489 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1301 aa)
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (216 aa)
FIS1Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (151 aa)
TBK1TANK binding kinase 1. (728 aa)
FOXO3Fork-head domain-containing protein. (587 aa)
K7FKZ4_PELSIProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (386 aa)
GABARAPL1GABA type A receptor associated protein like 1. (117 aa)
ULK1Unc-51 like autophagy activating kinase 1. (1030 aa)
MRASMuscle RAS oncogene homolog. (208 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (811 aa)
MFN2Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa)
ATF4Activating transcription factor 4. (356 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
RAB7ARAB7A, member RAS oncogene family. (207 aa)
TBC1D15TBC1 domain family member 15. (684 aa)
MITFMelanocyte inducing transcription factor. (451 aa)
RPS27AUbiquitin-like domain-containing protein. (140 aa)
SRCTyrosine-protein kinase. (533 aa)
BCL2L13BCL2 like 13. (470 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (390 aa)
MFN1Mitofusin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (752 aa)
FUNDC1FUN14 domain containing 1. (100 aa)
K7G5M9_PELSIUncharacterized protein. (120 aa)
RHOT2Ras homolog family member T2. (480 aa)
TAX1BP1Tax1 binding protein 1. (813 aa)
HRASHRas proto-oncogene, GTPase. (190 aa)
LOC102450218Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (273 aa)
KRASKRAS proto-oncogene, GTPase. (227 aa)
RRAS2RAS related 2. (173 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
OPTNOptineurin. (560 aa)
MAPK8Mitogen-activated protein kinase. (429 aa)
BNIP3BCL2 interacting protein 3. (205 aa)
BNIP3LBCL2 interacting protein 3 like. (199 aa)
CSNK2A1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa)
USP8Uncharacterized protein; Belongs to the peptidase C19 family. (861 aa)
Your Current Organism:
Pelodiscus sinensis
NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38
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