99 items (Pelodiscus sinensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TLR2	TIR domain-containing protein; Belongs to the Toll-like receptor family. (783 aa)
	LOC102457570	TIR domain-containing protein; Belongs to the Toll-like receptor family. (783 aa)
	K7F0D9_PELSI	Uncharacterized protein. (374 aa)
	K7F0I3_PELSI	Uncharacterized protein; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (307 aa)
	LOC102453465	Actin gamma 1. (375 aa)
	TFRC	Transferrin receptor. (762 aa)
	TUBA1B	Tubulin alpha 1b; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (574 aa)
	TUBA1C	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
	COLEC11	Collectin subfamily member 11. (289 aa)
	RAB5B	RAB5B, member RAS oncogene family. (217 aa)
	SCARB1	Scavenger receptor class B member 1; Belongs to the CD36 family. (454 aa)
	LOC102446337	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (442 aa)
	RAB7B	RAB7B, member RAS oncogene family. (200 aa)
	ITGB5	Integrin beta; Belongs to the integrin beta chain family. (796 aa)
	CTSL	Uncharacterized protein; Belongs to the peptidase C1 family. (338 aa)
	K7F7N0_PELSI	Ig-like domain-containing protein. (280 aa)
	TLR4	Toll like receptor 4; Belongs to the Toll-like receptor family. (833 aa)
	CANX	Uncharacterized protein. (606 aa)
	SEC22B	SEC22 homolog B, vesicle trafficking protein (gene/pseudogene); Belongs to the synaptobrevin family. (128 aa)
	PIKFYVE	Phosphoinositide kinase, FYVE-type zinc finger containing. (1498 aa)
	THBS1	Thrombospondin 1. (1176 aa)
	DYNC1LI1	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (454 aa)
	K7FB74_PELSI	Ig-like domain-containing protein; Belongs to the MHC class I family. (346 aa)
	TUBB1	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (453 aa)
	ATP6V0C	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (129 aa)
	SEC61G	SEC61 translocon gamma subunit. (66 aa)
	K7FHH2_PELSI	Uncharacterized protein; Belongs to the peptidase C1 family. (338 aa)
	ITGA2	VWFA domain-containing protein. (726 aa)
	K7FHZ3_PELSI	Ig-like domain-containing protein. (185 aa)
	TUBB3	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (459 aa)
	RAB5A	RAB5A, member RAS oncogene family. (215 aa)
	DYNC1H1	Dynein cytoplasmic 1 heavy chain 1. (4659 aa)
	K7FJR6_PELSI	Ig-like domain-containing protein. (242 aa)
	C1R	Complement C1r; Belongs to the peptidase S1 family. (708 aa)
	CYBB	Cytochrome b-245 beta chain. (572 aa)
	COLEC12	Collectin subfamily member 12. (734 aa)
	ITGB2	Integrin beta. (771 aa)
	NCF4	Neutrophil cytosolic factor 4. (352 aa)
	CTSS	Cathepsin S; Belongs to the peptidase C1 family. (330 aa)
	LOC102456554	C-type lectin domain-containing protein. (306 aa)
	THBS4	Uncharacterized protein. (951 aa)
	LOC102456804	C-type lectin domain-containing protein. (248 aa)
	ATP6V1B2	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (502 aa)
	ATP6V1C1	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (382 aa)
	K7FRL7_PELSI	Ig-like domain-containing protein. (117 aa)
	K7FRW5_PELSI	Uncharacterized protein. (755 aa)
	THBS2	Thrombospondin 2. (1182 aa)
	LOC102454956	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (427 aa)
	TUBB2A	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
	PLA2R1	Phospholipase A2 receptor 1. (1457 aa)
	NCF2	Neutrophil cytosolic factor 2. (526 aa)
	RAB7A	RAB7A, member RAS oncogene family. (207 aa)
	NCF1	Neutrophil cytosolic factor 1. (390 aa)
	LOC102450295	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (414 aa)
	SFTPD	Surfactant protein D. (373 aa)
	K7FZR0_PELSI	Uncharacterized protein. (314 aa)
	LOC102456381	Uncharacterized protein. (451 aa)
	K7FZX6_PELSI	Uncharacterized protein. (314 aa)
	ATP6V0D1	ATPase H+ transporting V0 subunit d1. (364 aa)
	PIK3C3	Phosphatidylinositol 3-kinase catalytic subunit type 3. (864 aa)
	RAC1	Rac family small GTPase 1. (186 aa)
	ATP6V1E1	Uncharacterized protein. (212 aa)
	CALR	Calreticulin. (392 aa)
	LOC102445290	C-type lectin domain-containing protein. (233 aa)
	RILP	RH2 domain-containing protein. (69 aa)
	TUBB6	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
	LOC102454048	Uncharacterized protein. (573 aa)
	ATP6V0E1	V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (81 aa)
	CALR3	Calreticulin. (388 aa)
	LAMP1	Lysosomal associated membrane protein 1. (397 aa)
	ATP6V0D2	ATPase H+ transporting V0 subunit d2. (176 aa)
	STX12	Syntaxin 12; Belongs to the syntaxin family. (265 aa)
	SEC61A1	SEC61 translocon alpha 1 subunit. (476 aa)
	M6PR	Mannose-6-phosphate receptor, cation dependent. (277 aa)
	STX7	Syntaxin 7; Belongs to the syntaxin family. (258 aa)
	TUBB4A	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (406 aa)
	DYNC2H1	Dynein cytoplasmic 2 heavy chain 1. (4313 aa)
	LOC102457342	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (455 aa)
	ATP6V1D	ATPase H+ transporting V1 subunit D. (229 aa)
	TUBA8	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
	RAB5C	Uncharacterized protein. (216 aa)
	ITGAV	Integrin subunit alpha V; Belongs to the integrin alpha chain family. (1046 aa)
	ATP6V0A4	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (839 aa)
	LOC102446295	Ig-like domain-containing protein; Belongs to the MHC class I family. (240 aa)
	ATP6V1C2	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (386 aa)
	VAMP3	Vesicle associated membrane protein 3. (98 aa)
	EPX	Eosinophil peroxidase. (706 aa)
	C3	Uncharacterized protein. (1664 aa)
	K7GDT8_PELSI	ATP-synt_ab domain-containing protein. (322 aa)
	STX18	Syntaxin 18. (329 aa)
	ATP6V1G1	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (135 aa)
	ATP6V0A1	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (845 aa)
	ATP6V1H	V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (480 aa)
	ATP6V1A	ATPase H+ transporting V1 subunit A. (617 aa)
	LOC102444982	Uncharacterized protein. (1455 aa)
	DYNC1LI2	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (470 aa)
	DYNC1I1	Dynein cytoplasmic 1 intermediate chain 1. (628 aa)
	EEA1	Early endosome antigen 1. (1409 aa)
	CD36	CD36 molecule; Belongs to the CD36 family. (479 aa)

Your Current Organism:

Pelodiscus sinensis

NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP6V0A1	ATP6V0A4	ENSPSIP00000018978	ENSPSIP00000017376	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.901
ATP6V0A1	ATP6V0C	ENSPSIP00000018978	ENSPSIP00000006145	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.996
ATP6V0A1	ATP6V0D1	ENSPSIP00000018978	ENSPSIP00000013629	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	ATPase H+ transporting V0 subunit d1.	0.992
ATP6V0A1	ATP6V0D2	ENSPSIP00000018978	ENSPSIP00000015395	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	ATPase H+ transporting V0 subunit d2.	0.992
ATP6V0A1	ATP6V0E1	ENSPSIP00000018978	ENSPSIP00000015209	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.962
ATP6V0A1	ATP6V1A	ENSPSIP00000018978	ENSPSIP00000019267	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	ATPase H+ transporting V1 subunit A.	0.901
ATP6V0A1	ATP6V1B2	ENSPSIP00000018978	ENSPSIP00000010255	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	0.945
ATP6V0A1	ATP6V1C1	ENSPSIP00000018978	ENSPSIP00000010546	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.950
ATP6V0A1	ATP6V1C2	ENSPSIP00000018978	ENSPSIP00000017740	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.907
ATP6V0A1	ATP6V1D	ENSPSIP00000018978	ENSPSIP00000016553	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	ATPase H+ transporting V1 subunit D.	0.957
ATP6V0A1	ATP6V1E1	ENSPSIP00000018978	ENSPSIP00000014401	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Uncharacterized protein.	0.981
ATP6V0A1	ATP6V1G1	ENSPSIP00000018978	ENSPSIP00000018778	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.963
ATP6V0A1	ATP6V1H	ENSPSIP00000018978	ENSPSIP00000019173	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system.	0.994
ATP6V0A1	K7GDT8_PELSI	ENSPSIP00000018978	ENSPSIP00000018449	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	ATP-synt_ab domain-containing protein.	0.852
ATP6V0A1	LOC102456381	ENSPSIP00000018978	ENSPSIP00000013552	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Uncharacterized protein.	0.981
ATP6V0A4	ATP6V0A1	ENSPSIP00000017376	ENSPSIP00000018978	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.901
ATP6V0A4	ATP6V0C	ENSPSIP00000017376	ENSPSIP00000006145	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.996
ATP6V0A4	ATP6V0D1	ENSPSIP00000017376	ENSPSIP00000013629	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	ATPase H+ transporting V0 subunit d1.	0.992
ATP6V0A4	ATP6V0D2	ENSPSIP00000017376	ENSPSIP00000015395	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	ATPase H+ transporting V0 subunit d2.	0.992
ATP6V0A4	ATP6V0E1	ENSPSIP00000017376	ENSPSIP00000015209	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.962