STRINGSTRING
RHOG RHOG LOC102456623 LOC102456623 RAB9A RAB9A JUN JUN TLR2 TLR2 TLR5 TLR5 LOC102457570 LOC102457570 K7F0D9_PELSI K7F0D9_PELSI RHOH RHOH ARF6 ARF6 LOC102458580 LOC102458580 RAB9B RAB9B LOC102453465 LOC102453465 NCKAP1 NCKAP1 KPNA3 KPNA3 PIK3C2G PIK3C2G PIK3CB PIK3CB LOC106731249 LOC106731249 RAB5B RAB5B VPS11 VPS11 MAPK1 MAPK1 BCL2 BCL2 LEF1 LEF1 RAB7B RAB7B TLR4 TLR4 CYFIP2 CYFIP2 PFN1 PFN1 TRADD TRADD FLNB FLNB DNM2 DNM2 K7FA65_PELSI K7FA65_PELSI DYNC1LI1 DYNC1LI1 PIK3CD PIK3CD PAK1 PAK1 FADD FADD SKP1 SKP1 TCF7 TCF7 PLEKHM1 PLEKHM1 TNF TNF AKT3 AKT3 MAPK10 MAPK10 IKBKB IKBKB PFN2 PFN2 LOC102457934 LOC102457934 LOC102459140 LOC102459140 LOC102462633 LOC102462633 PFN4 PFN4 LOC102455915 LOC102455915 MAP2K2 MAP2K2 PIK3CG PIK3CG CHUK CHUK K7FGD1_PELSI K7FGD1_PELSI SNX18 SNX18 MAPK14 MAPK14 K7FH17_PELSI K7FH17_PELSI MAPK13 MAPK13 TNFSF10 TNFSF10 ARPC5L ARPC5L MYL7 MYL7 RAB5A RAB5A DYNC1H1 DYNC1H1 CYFIP1 CYFIP1 K7FJ02_PELSI K7FJ02_PELSI PTPRC PTPRC CYTH4 CYTH4 AKT1 AKT1 KLC1 KLC1 KPNA4 KPNA4 MYD88 MYD88 MYC MYC DYNLRB1 DYNLRB1 NFKB1 NFKB1 FYCO1 FYCO1 RPS3 RPS3 LOC102454632 LOC102454632 VPS39 VPS39 K7FQ12_PELSI K7FQ12_PELSI DYNLL2 DYNLL2 EXOC5 EXOC5 NFKBIA NFKBIA EXOC4 EXOC4 LOC102455743 LOC102455743 S100A10 S100A10 RIPK2 RIPK2 ARF1 ARF1 RAF1 RAF1 TCF7L1 TCF7L1 DYNLT3 DYNLT3 MYLPF MYLPF HSP90B1 HSP90B1 GCC2 GCC2 LOC102448753 LOC102448753 RHOJ RHOJ ROCK2 ROCK2 RIPK1 RIPK1 DYNC2LI1 DYNC2LI1 CSE1L CSE1L WASF3 WASF3 TRAF6 TRAF6 ARPC1A ARPC1A MAP2K3 MAP2K3 K7FWT7_PELSI K7FWT7_PELSI TXN2 TXN2 TAB1 TAB1 SNX9 SNX9 RAB7A RAB7A RHOB RHOB MAP2K1 MAP2K1 IKBKG IKBKG PODXL PODXL NOD1 NOD1 ARPC3 ARPC3 ARPC2 ARPC2 EXOC2 EXOC2 PIK3C2A PIK3C2A MYO6 MYO6 PIK3C3 PIK3C3 LOC102444442 LOC102444442 RAC1 RAC1 WASL WASL ANXA2 ANXA2 TAB3 TAB3 CYTH3 CYTH3 ARHGEF26 ARHGEF26 VPS33A VPS33A ELMO2 ELMO2 IRAK4 IRAK4 PAK3 PAK3 RILP RILP MAP2K4 MAP2K4 BAK1 BAK1 LOC102459066 LOC102459066 DYNLL1 DYNLL1 MAPK11 MAPK11 M6PR M6PR TRAF2 TRAF2 VPS18 VPS18 TIRAP TIRAP MYL10 MYL10 MAPK12 MAPK12 PIK3CA PIK3CA LOC102449094 LOC102449094 DYNC2H1 DYNC2H1 HRAS HRAS RAB5C RAB5C K7G9R9_PELSI K7G9R9_PELSI RHOA RHOA MLKL MLKL MAPK9 MAPK9 PLEKHM2 PLEKHM2 MAPK8 MAPK8 TAB2 TAB2 ACBD3 ACBD3 CASP7 CASP7 MYL9 MYL9 FBXO22 FBXO22 MAP2K7 MAP2K7 CASP3 CASP3 ELMO1 ELMO1 KPNA1 KPNA1 IL18 IL18 MYL5 MYL5 VPS41 VPS41 MAP2K6 MAP2K6 FOS FOS DYNLT1 DYNLT1 RALA RALA HSP90AB1 HSP90AB1 LOC102458875 LOC102458875 DYNC1LI2 DYNC1LI2 LOC102455941 LOC102455941 HSP90AA1 HSP90AA1 TCF7L2 TCF7L2 DYNC1I1 DYNC1I1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RHOGRas homolog family member G. (191 aa)
LOC102456623Uncharacterized protein. (191 aa)
RAB9ARAB9A, member RAS oncogene family. (201 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (314 aa)
TLR2TIR domain-containing protein; Belongs to the Toll-like receptor family. (783 aa)
TLR5TIR domain-containing protein. (860 aa)
LOC102457570TIR domain-containing protein; Belongs to the Toll-like receptor family. (783 aa)
K7F0D9_PELSIUncharacterized protein. (374 aa)
RHOHRas homolog family member H. (191 aa)
ARF6ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
LOC102458580Uncharacterized protein. (198 aa)
RAB9BRAB9B, member RAS oncogene family. (201 aa)
LOC102453465Actin gamma 1. (375 aa)
NCKAP1NCK associated protein 1. (1133 aa)
KPNA3Karyopherin subunit alpha 3. (434 aa)
PIK3C2GPhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma; Belongs to the PI3/PI4-kinase family. (1019 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
LOC106731249Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
RAB5BRAB5B, member RAS oncogene family. (217 aa)
VPS11Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (877 aa)
MAPK1Mitogen-activated protein kinase. (322 aa)
BCL2BCL2 apoptosis regulator. (232 aa)
LEF1Lymphoid enhancer binding protein 1 (LEF-1) homologue. (398 aa)
RAB7BRAB7B, member RAS oncogene family. (200 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (833 aa)
CYFIP2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1254 aa)
PFN1Profilin; Belongs to the profilin family. (141 aa)
TRADDTNFRSF1A associated via death domain. (304 aa)
FLNBFilamin B. (2635 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (870 aa)
K7FA65_PELSITPR_REGION domain-containing protein. (553 aa)
DYNC1LI1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (454 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1066 aa)
PAK1Non-specific serine/threonine protein kinase. (545 aa)
FADDFas associated via death domain. (191 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
TCF7Transcription factor 7. (342 aa)
PLEKHM1Pleckstrin homology and RUN domain containing M1. (928 aa)
TNFTumor necrosis factor. (229 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
MAPK10Mitogen-activated protein kinase. (426 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (714 aa)
PFN2Profilin; Belongs to the profilin family. (97 aa)
LOC102457934Uncharacterized protein. (172 aa)
LOC102459140Uncharacterized protein. (172 aa)
LOC102462633Uncharacterized protein. (428 aa)
PFN4Profilin; Belongs to the profilin family. (124 aa)
LOC102455915PDZ domain-containing protein. (224 aa)
MAP2K2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (397 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1106 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (716 aa)
K7FGD1_PELSIUncharacterized protein. (725 aa)
SNX18Sorting nexin 18. (383 aa)
MAPK14Mitogen-activated protein kinase. (321 aa)
K7FH17_PELSIUncharacterized protein; Belongs to the peptidase C14A family. (244 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
TNFSF10TNF superfamily member 10; Belongs to the tumor necrosis factor family. (309 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (101 aa)
MYL7Myosin light chain 7. (148 aa)
RAB5ARAB5A, member RAS oncogene family. (215 aa)
DYNC1H1Dynein cytoplasmic 1 heavy chain 1. (4659 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
K7FJ02_PELSIPhosphatidylinositol 3-kinase catalytic subunit type 3. (787 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (736 aa)
CYTH4Cytohesin 4. (406 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
KLC1Uncharacterized protein. (623 aa)
KPNA4Importin subunit alpha; Belongs to the importin alpha family. (521 aa)
MYD88MYD88 innate immune signal transduction adaptor. (186 aa)
MYCMYC proto-oncogene, bHLH transcription factor. (324 aa)
DYNLRB1Dynein light chain roadblock. (96 aa)
NFKB1Nuclear factor kappa B subunit 1. (993 aa)
FYCO1RUN domain-containing protein. (956 aa)
RPS3KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (243 aa)
LOC102454632Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (104 aa)
VPS39VPS39 subunit of HOPS complex. (865 aa)
K7FQ12_PELSIInterleukin-1. (182 aa)
DYNLL2Dynein light chain. (91 aa)
EXOC5Exocyst complex component 5. (708 aa)
NFKBIAANK_REP_REGION domain-containing protein. (238 aa)
EXOC4Exocyst complex component 4. (950 aa)
LOC102455743Uncharacterized protein; Belongs to the peptidase C14A family. (237 aa)
S100A10S100 calcium binding protein A10; Belongs to the S-100 family. (106 aa)
RIPK2Receptor interacting serine/threonine kinase 2. (562 aa)
ARF1ADP ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family. (192 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (648 aa)
TCF7L1Transcription factor 7 like 1. (215 aa)
DYNLT3Dynein light chain Tctex-type 3. (112 aa)
MYLPFMyosin light chain, phosphorylatable, fast skeletal muscle. (168 aa)
HSP90B1Heat shock protein 90 beta family member 1. (792 aa)
GCC2GRIP and coiled-coil domain containing 2. (1667 aa)
LOC102448753Uncharacterized protein. (611 aa)
RHOJRas homolog family member J. (214 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1360 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (716 aa)
DYNC2LI1Dynein cytoplasmic 2 light intermediate chain 1. (315 aa)
CSE1LChromosome segregation 1 like. (983 aa)
WASF3WASP family member 3. (501 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (547 aa)
ARPC1AActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (370 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (337 aa)
K7FWT7_PELSIProtein kinase domain-containing protein. (174 aa)
TXN2Thioredoxin 2. (199 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (563 aa)
SNX9Sorting nexin. (596 aa)
RAB7ARAB7A, member RAS oncogene family. (207 aa)
RHOBRas homolog family member B. (196 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (395 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (585 aa)
PODXLPodocalyxin like. (535 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (950 aa)
ARPC3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (283 aa)
EXOC2Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (924 aa)
PIK3C2APhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family. (1690 aa)
MYO6Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1284 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (864 aa)
LOC102444442Uncharacterized protein. (252 aa)
RAC1Rac family small GTPase 1. (186 aa)
WASLWASP like actin nucleation promoting factor. (502 aa)
ANXA2Annexin. (367 aa)
TAB3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (706 aa)
CYTH3Cytohesin 3. (388 aa)
ARHGEF26Rho guanine nucleotide exchange factor 26. (867 aa)
VPS33AUncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (569 aa)
ELMO2Engulfment and cell motility 2. (710 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (464 aa)
PAK3Non-specific serine/threonine protein kinase. (560 aa)
RILPRH2 domain-containing protein. (69 aa)
MAP2K4Mitogen-activated protein kinase kinase 4. (328 aa)
BAK1BCL2 antagonist/killer 1. (213 aa)
LOC102459066Uncharacterized protein. (196 aa)
DYNLL1Dynein light chain. (89 aa)
MAPK11Mitogen-activated protein kinase. (361 aa)
M6PRMannose-6-phosphate receptor, cation dependent. (277 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (511 aa)
VPS18VPS18 core subunit of CORVET and HOPS complexes. (974 aa)
TIRAPTIR domain containing adaptor protein. (232 aa)
MYL10Uncharacterized protein. (166 aa)
MAPK12Mitogen-activated protein kinase. (364 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1029 aa)
LOC102449094WH2 domain-containing protein. (446 aa)
DYNC2H1Dynein cytoplasmic 2 heavy chain 1. (4313 aa)
HRASHRas proto-oncogene, GTPase. (190 aa)
RAB5CUncharacterized protein. (216 aa)
K7G9R9_PELSIUncharacterized protein. (650 aa)
RHOAUncharacterized protein. (202 aa)
MLKLUncharacterized protein. (256 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
PLEKHM2Pleckstrin homology and RUN domain containing M2. (901 aa)
MAPK8Mitogen-activated protein kinase. (429 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (692 aa)
ACBD3Acyl-CoA binding domain containing 3. (377 aa)
CASP7Caspase 7; Belongs to the peptidase C14A family. (312 aa)
MYL9Myosin light chain 9. (172 aa)
FBXO22F-box protein 22. (414 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (396 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (286 aa)
ELMO1Engulfment and cell motility 1. (727 aa)
KPNA1Importin subunit alpha; Belongs to the importin alpha family. (538 aa)
IL18Interleukin 18. (200 aa)
MYL5Myosin light chain 5. (172 aa)
VPS41Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (854 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (374 aa)
DYNLT1Dynein light chain Tctex-type 1. (113 aa)
RALARAS like proto-oncogene A. (206 aa)
HSP90AB1Heat shock protein 90 alpha family class B member 1. (683 aa)
LOC102458875Uncharacterized protein. (403 aa)
DYNC1LI2Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (470 aa)
LOC102455941Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (121 aa)
HSP90AA1Heat shock protein 90 alpha family class A member 1. (728 aa)
TCF7L2Transcription factor 7 like 2. (602 aa)
DYNC1I1Dynein cytoplasmic 1 intermediate chain 1. (628 aa)
Your Current Organism:
Pelodiscus sinensis
NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38
Server load: low (30%) [HD]