(11 nodes) Phenylalanine metabolism network (Rufibacter sp. DG31D)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AKQ44905.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (360 aa)
	AKQ45606.1	enoyl-CoA hydratase; Catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (683 aa)
	AKQ45607.1	Carbonic anhydrase; Derived by automated computational analysis using gene prediction method: Protein Homology. (197 aa)
	AKQ47554.1	Catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (401 aa)
	AKQ45609.1	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (261 aa)
	AKQ45610.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa)
	AKQ47555.1	Phenylacetic acid degradation protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (267 aa)
	paaB	phenylacetate-CoA oxygenase; With PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; involved in phenylacetate degradation; Derived by automated computational analysis using gene prediction method: Protein Homology. (95 aa)
	AKQ45612.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa)
	AKQ45613.1	Phenylacetic acid degradation protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (358 aa)
	AKQ45856.1	Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (353 aa)

Your Current Organism:

Rufibacter sp. DG31D

NCBI taxonomy Id: 1379910
Other names: R. sp. DG31D

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKQ44905.1	AKQ45606.1	TH63_03540	TH63_08000	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	enoyl-CoA hydratase; Catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.451
AKQ44905.1	AKQ45609.1	TH63_03540	TH63_08020	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family.	0.904
AKQ44905.1	AKQ45610.1	TH63_03540	TH63_08025	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.957
AKQ44905.1	AKQ45612.1	TH63_03540	TH63_08040	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.971
AKQ44905.1	AKQ45613.1	TH63_03540	TH63_08045	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phenylacetic acid degradation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.917
AKQ44905.1	AKQ45856.1	TH63_03540	TH63_09715	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.916
AKQ44905.1	AKQ47555.1	TH63_03540	TH63_08030	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phenylacetic acid degradation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.971
AKQ44905.1	paaB	TH63_03540	TH63_08035	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	phenylacetate-CoA oxygenase; With PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; involved in phenylacetate degradation; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.972
AKQ45606.1	AKQ44905.1	TH63_08000	TH63_03540	enoyl-CoA hydratase; Catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.451
AKQ45606.1	AKQ45607.1	TH63_08000	TH63_08005	enoyl-CoA hydratase; Catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	Carbonic anhydrase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.790
AKQ45606.1	AKQ45609.1	TH63_08000	TH63_08020	enoyl-CoA hydratase; Catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family.	0.976
AKQ45606.1	AKQ45610.1	TH63_08000	TH63_08025	enoyl-CoA hydratase; Catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.918
AKQ45606.1	AKQ45612.1	TH63_08000	TH63_08040	enoyl-CoA hydratase; Catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.899
AKQ45606.1	AKQ45613.1	TH63_08000	TH63_08045	enoyl-CoA hydratase; Catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phenylacetic acid degradation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.888
AKQ45606.1	AKQ45856.1	TH63_08000	TH63_09715	enoyl-CoA hydratase; Catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.677
AKQ45606.1	AKQ47554.1	TH63_08000	TH63_08010	enoyl-CoA hydratase; Catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	Catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.	0.825
AKQ45606.1	AKQ47555.1	TH63_08000	TH63_08030	enoyl-CoA hydratase; Catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phenylacetic acid degradation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.908
AKQ45606.1	paaB	TH63_08000	TH63_08035	enoyl-CoA hydratase; Catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	phenylacetate-CoA oxygenase; With PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; involved in phenylacetate degradation; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.919
AKQ45607.1	AKQ45606.1	TH63_08005	TH63_08000	Carbonic anhydrase; Derived by automated computational analysis using gene prediction method: Protein Homology.	enoyl-CoA hydratase; Catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.790
AKQ45607.1	AKQ45609.1	TH63_08005	TH63_08020	Carbonic anhydrase; Derived by automated computational analysis using gene prediction method: Protein Homology.	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family.	0.698