STRINGSTRING
AKQ46161.1 AKQ46161.1 AKQ44393.1 AKQ44393.1 eno eno AKQ44631.1 AKQ44631.1 aroC aroC leuC leuC leuD leuD hutU hutU AKQ45073.1 AKQ45073.1 AKQ45075.1 AKQ45075.1 uxuA uxuA AKQ45335.1 AKQ45335.1 AKQ45337.1 AKQ45337.1 trpB trpB trpA trpA dapA dapA AKQ45497.1 AKQ45497.1 mgsA mgsA hisB hisB AKQ45605.1 AKQ45605.1 AKQ45609.1 AKQ45609.1 AKQ45765.1 AKQ45765.1 AKQ47611.1 AKQ47611.1 AKQ45959.1 AKQ45959.1 AKQ47625.1 AKQ47625.1 AKQ46082.1 AKQ46082.1 AKQ46181.1 AKQ46181.1 AKQ46199.1 AKQ46199.1 aroQ aroQ lpxC lpxC AKQ46384.1 AKQ46384.1 AKQ46430.1 AKQ46430.1 uxuA-2 uxuA-2 AKQ46653.1 AKQ46653.1 AKQ46760.1 AKQ46760.1 AKQ46763.1 AKQ46763.1 AKQ46929.1 AKQ46929.1 fumC fumC AKQ47107.1 AKQ47107.1 AKQ47121.1 AKQ47121.1 AKQ47229.1 AKQ47229.1 nnrD nnrD murQ murQ nth nth
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AKQ46161.16-pyruvoyl tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (147 aa)
AKQ44393.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (130 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (425 aa)
AKQ44631.16-pyruvoyl tetrahydrobiopterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (135 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (360 aa)
leuCIsopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (465 aa)
leuD3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (198 aa)
hutUUrocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (561 aa)
AKQ45073.1Pectate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (495 aa)
AKQ45075.1Pectate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (466 aa)
uxuAMannonate dehydratase; Catalyzes the dehydration of D-mannonate. (390 aa)
AKQ45335.1Carbonate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (212 aa)
AKQ45337.1Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (439 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (398 aa)
trpAHypothetical protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (258 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (292 aa)
AKQ45497.1Threonine synthase; Catalyzes the formation of L-threonine from O-phospho-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (400 aa)
mgsAMethylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. (126 aa)
hisBImidazoleglycerol-phosphate dehydratase; Catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. (364 aa)
AKQ45605.1enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (254 aa)
AKQ45609.1enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (261 aa)
AKQ45765.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (259 aa)
AKQ47611.1Carbonate dehydratase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (206 aa)
AKQ45959.1Aconitate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (757 aa)
AKQ47625.1methylglutaconyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (265 aa)
AKQ46082.16-pyruvoyl tetrahydrobiopterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (138 aa)
AKQ46181.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (813 aa)
AKQ46199.13-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (346 aa)
aroQ3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (152 aa)
lpxChydroxymyristoyl-ACP dehydratase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily. (464 aa)
AKQ46384.1Endonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology. (235 aa)
AKQ46430.1Pterin-4-alpha-carbinolamine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (110 aa)
uxuA-2Mannonate dehydratase; Catalyzes the dehydration of D-mannonate. (392 aa)
AKQ46653.1DNA-formamidopyrimidine glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (271 aa)
AKQ46760.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (65 aa)
AKQ46763.1Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. (326 aa)
AKQ46929.1dTDP-glucose 4,6-dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (348 aa)
fumCFumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (465 aa)
AKQ47107.1Pterin-4-alpha-carbinolamine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (86 aa)
AKQ47121.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (140 aa)
AKQ47229.1uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (263 aa)
nnrDCarbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] (504 aa)
murQN-acetylmuramic acid-6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. (268 aa)
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (224 aa)
Your Current Organism:
Rufibacter sp. DG31D
NCBI taxonomy Id: 1379910
Other names: R. sp. DG31D
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