STRINGSTRING
AKQ46760.1 AKQ46760.1 kmo kmo kynU kynU AKQ46841.1 AKQ46841.1 AKQ47351.1 AKQ47351.1 fumC fumC AKQ47378.1 AKQ47378.1 AKQ44455.1 AKQ44455.1 aroE aroE dapF dapF AKQ44587.1 AKQ44587.1 AKQ44589.1 AKQ44589.1 AKQ44636.1 AKQ44636.1 AKQ44637.1 AKQ44637.1 AKQ44670.1 AKQ44670.1 aroC aroC gltD gltD AKQ45016.1 AKQ45016.1 nadA nadA hutU hutU AKQ45061.1 AKQ45061.1 AKQ45265.1 AKQ45265.1 AKQ45306.1 AKQ45306.1 AKQ45360.1 AKQ45360.1 dapA dapA AKQ45484.1 AKQ45484.1 AKQ47561.1 AKQ47561.1 AKQ45786.1 AKQ45786.1 AKQ45834.1 AKQ45834.1 lysA lysA AKQ45887.1 AKQ45887.1 AKQ47610.1 AKQ47610.1 AKQ45964.1 AKQ45964.1 AKQ46031.1 AKQ46031.1 AKQ46032.1 AKQ46032.1 AKQ46125.1 AKQ46125.1 AKQ47681.1 AKQ47681.1 AKQ46200.1 AKQ46200.1 AKQ46218.1 AKQ46218.1 aroQ aroQ AKQ46271.1 AKQ46271.1 AKQ46362.1 AKQ46362.1 AKQ46583.1 AKQ46583.1 aroK aroK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AKQ46760.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (65 aa)
kmoKynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. (449 aa)
kynUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (423 aa)
AKQ46841.12-hydroxymuconic semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (480 aa)
AKQ47351.1Peptidase dimerization domain protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (455 aa)
fumCFumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (465 aa)
AKQ47378.1Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. (757 aa)
AKQ44455.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (461 aa)
aroEAroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; Derived by automated computational analysis using gene prediction method: Protein Homology. (245 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (256 aa)
AKQ44587.1N-acyl-L-amino acid amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (401 aa)
AKQ44589.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (514 aa)
AKQ44636.1N-acyl-L-amino acid amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (437 aa)
AKQ44637.1N-acyl-L-amino acid amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (440 aa)
AKQ44670.1Acetylornithine deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (354 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (360 aa)
gltDGlutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; Derived by automated computational analysis using gene prediction method: Protein Homology. (484 aa)
AKQ45016.1Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1501 aa)
nadAQuinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (328 aa)
hutUUrocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (561 aa)
AKQ45061.1Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (858 aa)
AKQ45265.1Histidine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (501 aa)
AKQ45306.1Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. (238 aa)
AKQ45360.1Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (396 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (292 aa)
AKQ45484.12,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the transferase hexapeptide repeat family. (272 aa)
AKQ47561.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (533 aa)
AKQ45786.1Peptidase M20; Derived by automated computational analysis using gene prediction method: Protein Homology. (509 aa)
AKQ45834.1Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (444 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (381 aa)
AKQ45887.1Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (411 aa)
AKQ47610.1Succinate-semialdehyde dehydrogenase; In Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (457 aa)
AKQ45964.12-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (161 aa)
AKQ46031.1Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (432 aa)
AKQ46032.1Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1017 aa)
AKQ46125.1Iron-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (73 aa)
AKQ47681.13-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (398 aa)
AKQ46200.1Proline dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (392 aa)
AKQ46218.1Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (429 aa)
aroQ3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (152 aa)
AKQ46271.1Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (425 aa)
AKQ46362.1Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (120 aa)
AKQ46583.11-pyrroline-5-carboxylate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (550 aa)
aroKHypothetical protein; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (167 aa)
Your Current Organism:
Rufibacter sp. DG31D
NCBI taxonomy Id: 1379910
Other names: R. sp. DG31D
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.