(9 nodes) Tyrosine metabolism network (Rufibacter sp. DG31D)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AKQ44849.1	Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (402 aa)
	hisC	Histidinol phosphate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (355 aa)
	AKQ45684.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (364 aa)
	AKQ47588.1	Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (336 aa)
	AKQ47600.1	4-hydroxyphenylpyruvate dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (366 aa)
	AKQ45866.1	2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (203 aa)
	AKQ47610.1	Succinate-semialdehyde dehydrogenase; In Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (457 aa)
	AKQ46331.1	Fumarylacetoacetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (427 aa)
	AKQ46769.1	Homogentisate 1,2-dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa)

Your Current Organism:

Rufibacter sp. DG31D

NCBI taxonomy Id: 1379910
Other names: R. sp. DG31D

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKQ44849.1	AKQ45684.1	TH63_03175	TH63_08505	Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.915
AKQ44849.1	AKQ47600.1	TH63_03175	TH63_09630	Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	4-hydroxyphenylpyruvate dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.914
AKQ44849.1	hisC	TH63_03175	TH63_07815	Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidinol phosphate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	0.914
AKQ45684.1	AKQ44849.1	TH63_08505	TH63_03175	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.915
AKQ45684.1	AKQ47600.1	TH63_08505	TH63_09630	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	4-hydroxyphenylpyruvate dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.914
AKQ45684.1	hisC	TH63_08505	TH63_07815	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidinol phosphate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	0.918
AKQ45866.1	AKQ46331.1	TH63_09780	TH63_12990	2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Fumarylacetoacetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.900
AKQ45866.1	AKQ46769.1	TH63_09780	TH63_15895	2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Homogentisate 1,2-dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.816
AKQ46331.1	AKQ45866.1	TH63_12990	TH63_09780	Fumarylacetoacetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.900
AKQ46331.1	AKQ46769.1	TH63_12990	TH63_15895	Fumarylacetoacetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Homogentisate 1,2-dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.951
AKQ46331.1	AKQ47600.1	TH63_12990	TH63_09630	Fumarylacetoacetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	4-hydroxyphenylpyruvate dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.851
AKQ46769.1	AKQ45866.1	TH63_15895	TH63_09780	Homogentisate 1,2-dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.816
AKQ46769.1	AKQ46331.1	TH63_15895	TH63_12990	Homogentisate 1,2-dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Fumarylacetoacetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.951
AKQ46769.1	AKQ47600.1	TH63_15895	TH63_09630	Homogentisate 1,2-dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	4-hydroxyphenylpyruvate dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.996
AKQ47600.1	AKQ44849.1	TH63_09630	TH63_03175	4-hydroxyphenylpyruvate dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.914
AKQ47600.1	AKQ45684.1	TH63_09630	TH63_08505	4-hydroxyphenylpyruvate dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.914
AKQ47600.1	AKQ46331.1	TH63_09630	TH63_12990	4-hydroxyphenylpyruvate dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Fumarylacetoacetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.851
AKQ47600.1	AKQ46769.1	TH63_09630	TH63_15895	4-hydroxyphenylpyruvate dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Homogentisate 1,2-dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.996
AKQ47600.1	hisC	TH63_09630	TH63_07815	4-hydroxyphenylpyruvate dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidinol phosphate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	0.917
hisC	AKQ44849.1	TH63_07815	TH63_03175	Histidinol phosphate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.914