(49 nodes) Ether lipid metabolism network (Pochonia chlamydosporia 170)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	VFPPC_07151	GYF domain-containing protein. (1439 aa)
	VFPPC_12306	Sn-1,2-diacylglycerol cholinephosphotransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (447 aa)
	VFPPC_11676	Sec14 cytosolic factor. (335 aa)
	VFPPC_14761	Phosphoesterase superfamily protein. (453 aa)
	VFPPC_10950	Short-chain dehydrogenase. (293 aa)
	VFPPC_10944	Cyclic nucleotide gated channel beta 1. (229 aa)
	VFPPC_10193	Non-hemolytic phospholipase C. (626 aa)
	VFPPC_10431	SWIB/MDM2 domain-containing protein. (288 aa)
	VFPPC_03787	Nadph-dependent 1-acyldihydroxyacetone phosphate reductase protein. (283 aa)
	VFPPC_09934	Non-hemolytic phospholipase C. (654 aa)
	VFPPC_10086	Putative phospholipase. (557 aa)
	VFPPC_10626	Patatin-like phospholipase. (971 aa)
	VFPPC_06723	Non-hemolytic phospholipase C. (645 aa)
	PAC1	Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family. (456 aa)
	VFPPC_02217	Cellular retinaldehyde-binding/triple function. (362 aa)
	VFPPC_07144	Potassium ion channel Yvc1. (654 aa)
	VFPPC_07084	MBOAT family protein; Belongs to the membrane-bound acyltransferase family. (538 aa)
	VFPPC_08759	Phospholipase A2, group VII. (601 aa)
	VFPPC_09795	Cupin-like domain-containing protein. (327 aa)
	VFPPC_09739	PAF acetylhydrolase family protein. (390 aa)
	VFPPC_09714	Patatin-like phospholipase domain-containing protein; Lipid hydrolase; Belongs to the PLPL family. (795 aa)
	VFPPC_05820	Catalytic protein. (664 aa)
	VFPPC_05930	Fungal specific transcription factor. (424 aa)
	VFPPC_14015	Putative phospholipase. (565 aa)
	PAC1-2	Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family. (470 aa)
	VFPPC_14267	Phosphatidylinositol transporter. (450 aa)
	VFPPC_07767	Sec14 cytosolic factor. (335 aa)
	VFPPC_07717	Lipase. (368 aa)
	VFPPC_14456	Platelet-activating factor acetylhydrolase, isoform II domain-containing protein. (299 aa)
	VFPPC_14458	Uncharacterized protein. (265 aa)
	VFPPC_14380	C2 domain-containing protein. (1199 aa)
	VFPPC_08567	Non-hemolytic phospholipase C. (649 aa)
	VFPPC_03955	Uncharacterized protein. (615 aa)
	VFPPC_04396	Short-chain dehydrogenase protein. (288 aa)
	VFPPC_04681	Short chain dehydrogenase reductase protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (279 aa)
	VFPPC_04753	Aminoalcoholphosphotransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (412 aa)
	VFPPC_11618	Patatin-like serine hydrolase. (588 aa)
	VFPPC_11938	Oxidoreductase,short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (289 aa)
	VFPPC_02964	C2 domain-containing protein. (1495 aa)
	VFPPC_03006	Uncharacterized protein. (440 aa)
	VFPPC_02647	Patatin-like phospholipase domain-containing protein; Lipid hydrolase; Belongs to the PLPL family. (752 aa)
	VFPPC_03558	Lysophospholipase. (799 aa)
	VFPPC_03150	Phospholipase. (1820 aa)
	VFPPC_03694	Oxidoreductase, short-chain dehydrogenase/reductase family; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (290 aa)
	VFPPC_03568	Phospholipase. (879 aa)
	VFPPC_03429	C2 domain-containing protein. (1200 aa)
	VFPPC_12974	Uncharacterized protein. (297 aa)
	VFPPC_18221	WD domain, g-beta repeat domain-containing protein. (1186 aa)
	VFPPC_17622	Uncharacterized protein. (138 aa)

Your Current Organism:

Pochonia chlamydosporia 170

NCBI taxonomy Id: 1380566
Other names: Metacordyceps chlamydosporia 170, P. chlamydosporia 170

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PAC1	VFPPC_03006	A0A179F5R1	A0A179FY11	Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family.	Uncharacterized protein.	0.794
PAC1	VFPPC_08759	A0A179F5R1	A0A179FBT9	Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family.	Phospholipase A2, group VII.	0.775
PAC1	VFPPC_10086	A0A179F5R1	A0A179F3J7	Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family.	Putative phospholipase.	0.775
PAC1	VFPPC_14015	A0A179F5R1	A0A179FID1	Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family.	Putative phospholipase.	0.775
PAC1-2	VFPPC_03006	A0A179FK55	A0A179FY11	Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family.	Uncharacterized protein.	0.794
PAC1-2	VFPPC_08759	A0A179FK55	A0A179FBT9	Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family.	Phospholipase A2, group VII.	0.775
PAC1-2	VFPPC_10086	A0A179FK55	A0A179F3J7	Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family.	Putative phospholipase.	0.775
PAC1-2	VFPPC_14015	A0A179FK55	A0A179FID1	Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family.	Putative phospholipase.	0.775
VFPPC_02217	VFPPC_03150	A0A179F7S1	A0A179G094	Cellular retinaldehyde-binding/triple function.	Phospholipase.	0.402
VFPPC_02217	VFPPC_03568	A0A179F7S1	A0A179G0L0	Cellular retinaldehyde-binding/triple function.	Phospholipase.	0.402
VFPPC_02217	VFPPC_03955	A0A179F7S1	A0A179FR14	Cellular retinaldehyde-binding/triple function.	Uncharacterized protein.	0.402
VFPPC_02647	VFPPC_03150	A0A179FYS5	A0A179G094	Patatin-like phospholipase domain-containing protein; Lipid hydrolase; Belongs to the PLPL family.	Phospholipase.	0.574
VFPPC_02647	VFPPC_03568	A0A179FYS5	A0A179G0L0	Patatin-like phospholipase domain-containing protein; Lipid hydrolase; Belongs to the PLPL family.	Phospholipase.	0.574
VFPPC_02647	VFPPC_03955	A0A179FYS5	A0A179FR14	Patatin-like phospholipase domain-containing protein; Lipid hydrolase; Belongs to the PLPL family.	Uncharacterized protein.	0.574
VFPPC_02647	VFPPC_04753	A0A179FYS5	A0A179FTV6	Patatin-like phospholipase domain-containing protein; Lipid hydrolase; Belongs to the PLPL family.	Aminoalcoholphosphotransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	0.611
VFPPC_02647	VFPPC_07084	A0A179FYS5	A0A179FAF6	Patatin-like phospholipase domain-containing protein; Lipid hydrolase; Belongs to the PLPL family.	MBOAT family protein; Belongs to the membrane-bound acyltransferase family.	0.665
VFPPC_02647	VFPPC_07717	A0A179FYS5	A0A179FLM5	Patatin-like phospholipase domain-containing protein; Lipid hydrolase; Belongs to the PLPL family.	Lipase.	0.408
VFPPC_02647	VFPPC_08759	A0A179FYS5	A0A179FBT9	Patatin-like phospholipase domain-containing protein; Lipid hydrolase; Belongs to the PLPL family.	Phospholipase A2, group VII.	0.545
VFPPC_02647	VFPPC_09714	A0A179FYS5	A0A179FEF8	Patatin-like phospholipase domain-containing protein; Lipid hydrolase; Belongs to the PLPL family.	Patatin-like phospholipase domain-containing protein; Lipid hydrolase; Belongs to the PLPL family.	0.768
VFPPC_02647	VFPPC_09739	A0A179FYS5	A0A179FE63	Patatin-like phospholipase domain-containing protein; Lipid hydrolase; Belongs to the PLPL family.	PAF acetylhydrolase family protein.	0.408