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pyrI pyrI pyrB pyrB KXB85174.1 KXB85174.1 carA carA KXB85176.1 KXB85176.1 KXB85183.1 KXB85183.1 purD purD folD folD purU purU purC purC KXB84835.1 KXB84835.1 KXB84837.1 KXB84837.1 purT purT fmt fmt KXB83380.1 KXB83380.1 KXB83295.1 KXB83295.1 KXB82794.1 KXB82794.1 purE purE pyrE pyrE KXB82314.1 KXB82314.1 pyrD pyrD purA purA KXB81470.1 KXB81470.1 purL purL KXB79065.1 KXB79065.1 purN purN
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
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textmining
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Your Input:
pyrIAspartate carbamoyltransferase, regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase. (156 aa)
pyrBKEGG: pru:PRU_0637 1.2e-146 pyrB; aspartate carbamoyltransferase K00609; Psort location: Cytoplasmic, score: 9.97; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (315 aa)
KXB85174.1KEGG: pmz:HMPREF0659_A5881 1.4e-257 class II glutamine amidotransferase; K00764 amidophosphoribosyltransferase; Psort location: Cytoplasmic, score: 8.96. (628 aa)
carAKEGG: pmz:HMPREF0659_A5880 4.3e-176 carA; carbamoyl-phosphate synthase, small subunit K01956; Psort location: Cytoplasmic, score: 9.97; Belongs to the CarA family. (358 aa)
KXB85176.1KEGG: pmz:HMPREF0659_A5879 0. carB; carbamoyl-phosphate synthase, large subunit K01955; Psort location: Cytoplasmic, score: 9.97. (1074 aa)
KXB85183.1Putative permease; KEGG: swp:swp_1190 2.8e-92 xanthine/uracil/vitamin C permease K06901; Psort location: CytoplasmicMembrane, score: 10.00. (433 aa)
purDKEGG: pru:PRU_1807 1.7e-190 purD; phosphoribosylamine--glycine ligase K01945; Psort location: Cytoplasmic, score: 9.97; Belongs to the GARS family. (422 aa)
folDTetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (292 aa)
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (287 aa)
purCKEGG: pmz:HMPREF0659_A6716 2.0e-155 purC; phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923; Psort location: Cytoplasmic, score: 8.96; Belongs to the SAICAR synthetase family. (316 aa)
KXB84835.1Hypothetical protein; KEGG: pru:PRU_0720 1.3e-192 phosphoribosylformylglycinamidine cyclo-ligase; K01933 phosphoribosylformylglycinamidine cyclo-ligase; Psort location: Cytoplasmic, score: 9.97. (393 aa)
KXB84837.1KEGG: pit:PIN17_A1653 7.6e-115 pyrF; orotidine 5'-phosphate decarboxylase K01591; Psort location: Cytoplasmic, score: 8.96. (273 aa)
purTPhosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (387 aa)
fmtmethionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (321 aa)
KXB83380.1AICARFT/IMPCHase bienzyme; KEGG: pru:PRU_1927 2.9e-193 phosphoribosylaminoimidazolecarboxamide formyltransferase; K00602 phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase; Psort location: Cytoplasmic, score: 9.97. (393 aa)
KXB83295.1Adenylosuccinate lyase; KEGG: pmz:HMPREF0659_A6153 2.3e-209 purB; adenylosuccinate lyase K01756; Psort location: Cytoplasmic, score: 9.97. (448 aa)
KXB82794.1MGS-like domain protein; KEGG: pru:PRU_1709 2.4e-88 IMP cyclohydrolase; K00602 phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase; Psort location: Cytoplasmic, score: 9.97. (197 aa)
purEPhosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (169 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (210 aa)
KXB82314.1KEGG: bhl:Bache_2300 2.0e-84 dihydroorotate oxidase B, electron transfer subunit K02823; Psort location: Cytoplasmic, score: 9.26. (258 aa)
pyrDDihydroorotate oxidase, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate. (302 aa)
purAAdenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (425 aa)
KXB81470.1KEGG: pit:PIN17_A1311 1.1e-51 5-formyltetrahydrofolate cyclo-ligase K01934; Psort location: Cytoplasmic, score: 8.96. (180 aa)
purLPutative phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1240 aa)
KXB79065.1Dihydroorotase; KEGG: pmz:HMPREF0659_A5999 5.9e-147 amidohydrolase family protein; K01465 dihydroorotase; Psort location: Cytoplasmic, score: 9.97. (443 aa)
purNPutative phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (192 aa)
Your Current Organism:
Prevotella sp. DNF00663
NCBI taxonomy Id: 1384078
Other names: P. sp. DNF00663
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