STRINGSTRING
pyrI pyrI pyrB pyrB carA carA KXB84912.1 KXB84912.1 KXB84837.1 KXB84837.1 dut dut pyrH pyrH pyrE pyrE udk udk KXB82314.1 KXB82314.1 pyrD pyrD KXB82235.1 KXB82235.1 pyrG pyrG KXB79182.1 KXB79182.1 KXB79065.1 KXB79065.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pyrIAspartate carbamoyltransferase, regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase. (156 aa)
pyrBKEGG: pru:PRU_0637 1.2e-146 pyrB; aspartate carbamoyltransferase K00609; Psort location: Cytoplasmic, score: 9.97; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (315 aa)
carAKEGG: pmz:HMPREF0659_A5880 4.3e-176 carA; carbamoyl-phosphate synthase, small subunit K01956; Psort location: Cytoplasmic, score: 9.97; Belongs to the CarA family. (358 aa)
KXB84912.1ATP-grasp domain protein; KEGG: pmz:HMPREF0659_A5893 4.9e-104 ATP-grasp domain protein; K01955 carbamoyl-phosphate synthase large subunit; Psort location: Cytoplasmic, score: 8.96. (334 aa)
KXB84837.1KEGG: pit:PIN17_A1653 7.6e-115 pyrF; orotidine 5'-phosphate decarboxylase K01591; Psort location: Cytoplasmic, score: 8.96. (273 aa)
dutPutative dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (144 aa)
pyrHUMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (236 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (210 aa)
udkUridine kinase; KEGG: pit:PIN17_A1417 6.6e-93 udk; uridine kinase K00876; Psort location: Cytoplasmic, score: 9.97. (211 aa)
KXB82314.1KEGG: bhl:Bache_2300 2.0e-84 dihydroorotate oxidase B, electron transfer subunit K02823; Psort location: Cytoplasmic, score: 9.26. (258 aa)
pyrDDihydroorotate oxidase, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate. (302 aa)
KXB82235.1Thymidylate synthase ThyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (292 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (535 aa)
KXB79182.1KEGG: pmz:HMPREF0659_A6372 2.8e-101 putative uracil phosphoribosyltransferase; K00761 uracil phosphoribosyltransferase; Psort location: Cytoplasmic, score: 9.97. (219 aa)
KXB79065.1Dihydroorotase; KEGG: pmz:HMPREF0659_A5999 5.9e-147 amidohydrolase family protein; K01465 dihydroorotase; Psort location: Cytoplasmic, score: 9.97. (443 aa)
Your Current Organism:
Prevotella sp. DNF00663
NCBI taxonomy Id: 1384078
Other names: P. sp. DNF00663
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