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pdxT pdxT KXB79396.1 KXB79396.1 KXB79466.1 KXB79466.1 proA proA proB proB proC proC KXB79484.1 KXB79484.1 argC argC KXB79481.1 KXB79481.1 KXB79480.1 KXB79480.1 argR argR KXB79924.1 KXB79924.1 cobQ cobQ speA speA argB argB argH argH KXB82249.1 KXB82249.1 guaA guaA pyrG pyrG purL purL KXB85174.1 KXB85174.1 carA carA hisH hisH KXB84912.1 KXB84912.1 KXB84949.1 KXB84949.1 KXB83165.1 KXB83165.1
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
pdxTPyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (190 aa)
KXB79396.1Renal dipeptidase family protein; KEGG: pru:PRU_2864 2.0e-201 amma-glutamyl hydrolase family peptidase; Psort location: Cytoplasmic, score: 8.96. (596 aa)
KXB79466.1N-acetylornithine carbamoyltransferase; KEGG: pru:PRU_2210 7.8e-145 transcarbamylase; K13043 N-succinyl-L-ornithine transcarbamylase; Psort location: Cytoplasmic, score: 9.97; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (320 aa)
proAGlutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (416 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (356 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (261 aa)
KXB79484.1KEGG: pru:PRU_2201 2.3e-152 argD; acetylornithine transaminase K00818; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (411 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (322 aa)
KXB79481.1KEGG: pru:PRU_2199 2.4e-191 argG; argininosuccinate synthase K01940; Psort location: Cytoplasmic, score: 9.97. (399 aa)
KXB79480.1Hypothetical protein; KEGG: zga:zobellia_1227 7.3e-55 GCN5-like N-acetyltransferase. (219 aa)
argRArginine repressor protein; Regulates arginine biosynthesis genes. (156 aa)
KXB79924.1Putative arginase; KEGG: asm:MOUSESFB_1140 1.2e-36 rocF; arginase; K01476 arginase; Psort location: Cytoplasmic, score: 9.97; Belongs to the arginase family. (281 aa)
cobQCobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (489 aa)
speAArginine 2-monooxygenase; Catalyzes the biosynthesis of agmatine from arginine. (630 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (257 aa)
argHArgininosuccinate lyase; KEGG: pru:PRU_2393 8.0e-207 argH; argininosuccinate lyase K01755; Psort location: Cytoplasmic, score: 9.97. (453 aa)
KXB82249.1Glutamate synthase; KEGG: pru:PRU_0699 0. gltA_1; glutamate synthase K00266; Psort location: Cytoplasmic, score: 9.97. (782 aa)
guaAGMP synthase domain protein; Catalyzes the synthesis of GMP from XMP. (514 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (535 aa)
purLPutative phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1240 aa)
KXB85174.1KEGG: pmz:HMPREF0659_A5881 1.4e-257 class II glutamine amidotransferase; K00764 amidophosphoribosyltransferase; Psort location: Cytoplasmic, score: 8.96. (628 aa)
carAKEGG: pmz:HMPREF0659_A5880 4.3e-176 carA; carbamoyl-phosphate synthase, small subunit K01956; Psort location: Cytoplasmic, score: 9.97; Belongs to the CarA family. (358 aa)
hisHImidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (199 aa)
KXB84912.1ATP-grasp domain protein; KEGG: pmz:HMPREF0659_A5893 4.9e-104 ATP-grasp domain protein; K01955 carbamoyl-phosphate synthase large subunit; Psort location: Cytoplasmic, score: 8.96. (334 aa)
KXB84949.1Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. (124 aa)
KXB83165.1KEGG: pru:PRU_1086 5.3e-107 cobB; cobyrinic acid a,c-diamide synthase; K02224 cobyrinic acid a,c-diamide synthase; Psort location: Cytoplasmic, score: 9.97. (404 aa)
Your Current Organism:
Prevotella sp. DNF00663
NCBI taxonomy Id: 1384078
Other names: P. sp. DNF00663
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