STRINGSTRING
cmk cmk KXB86029.1 KXB86029.1 pyrI pyrI pyrB pyrB carA carA KXB85176.1 KXB85176.1 KXB85185.1 KXB85185.1 KXB85238.1 KXB85238.1 KXB84912.1 KXB84912.1 KXB84935.1 KXB84935.1 KXB84837.1 KXB84837.1 KXB84748.1 KXB84748.1 KXB84820.1 KXB84820.1 KXB84821.1 KXB84821.1 KXB84041.1 KXB84041.1 dut dut KXB83440.1 KXB83440.1 KXB83332.1 KXB83332.1 KXB83356.1 KXB83356.1 KXB83357.1 KXB83357.1 tadA tadA pyrH pyrH tgt tgt KXB83146.1 KXB83146.1 pyrE pyrE KXB82545.1 KXB82545.1 KXB82424.1 KXB82424.1 surE surE udk udk KXB82311.1 KXB82311.1 KXB82314.1 KXB82314.1 pyrD pyrD KXB82235.1 KXB82235.1 KXB82251.1 KXB82251.1 groS groS pyrG pyrG KXB81472.1 KXB81472.1 KXB80847.1 KXB80847.1 KXB80864.1 KXB80864.1 KXB79405.1 KXB79405.1 KXB79182.1 KXB79182.1 KXB79065.1 KXB79065.1 tdk tdk KXB78435.1 KXB78435.1 KXB77863.1 KXB77863.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cmkCytidylate kinase; KEGG: pru:PRU_1828 4.5e-94 cmk; cytidylate kinase K00945; Psort location: Cytoplasmic, score: 9.97. (228 aa)
KXB86029.1TIGR00730 family protein; KEGG: rme:Rmet_0902 8.1e-24 putative Rossmann fold nucleotide-binding protein / Lysine decarboxylase family protein K06966; Psort location: Cytoplasmic, score: 8.96; Belongs to the LOG family. (178 aa)
pyrIAspartate carbamoyltransferase, regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase. (156 aa)
pyrBKEGG: pru:PRU_0637 1.2e-146 pyrB; aspartate carbamoyltransferase K00609; Psort location: Cytoplasmic, score: 9.97; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (315 aa)
carAKEGG: pmz:HMPREF0659_A5880 4.3e-176 carA; carbamoyl-phosphate synthase, small subunit K01956; Psort location: Cytoplasmic, score: 9.97; Belongs to the CarA family. (358 aa)
KXB85176.1KEGG: pmz:HMPREF0659_A5879 0. carB; carbamoyl-phosphate synthase, large subunit K01955; Psort location: Cytoplasmic, score: 9.97. (1074 aa)
KXB85185.1KEGG: pit:PIN17_A1181 2.0e-203 5'-nucleotidase; K01119 2',3'-cyclic-nucleotide 2'-phosphodiesterase; Psort location: Periplasmic, score: 9.76; Belongs to the 5'-nucleotidase family. (585 aa)
KXB85238.1Endonuclease/exonuclease/phosphatase family protein; Psort location: Cytoplasmic, score: 8.96. (317 aa)
KXB84912.1ATP-grasp domain protein; KEGG: pmz:HMPREF0659_A5893 4.9e-104 ATP-grasp domain protein; K01955 carbamoyl-phosphate synthase large subunit; Psort location: Cytoplasmic, score: 8.96. (334 aa)
KXB84935.1Transporter, major facilitator family protein; KEGG: eci:UTI89_C4210 1.5e-61 yicJ; transporter K03292; Psort location: CytoplasmicMembrane, score: 10.00. (466 aa)
KXB84837.1KEGG: pit:PIN17_A1653 7.6e-115 pyrF; orotidine 5'-phosphate decarboxylase K01591; Psort location: Cytoplasmic, score: 8.96. (273 aa)
KXB84748.1Hypothetical protein; KEGG: eel:EUBELI_01147 3.5e-39 cytidylate kinase; K00945 cytidylate kinase; Psort location: Cytoplasmic, score: 8.96. (212 aa)
KXB84820.1Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (839 aa)
KXB84821.1Ribonucleoside-diphosphate reductase, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (349 aa)
KXB84041.1Endonuclease/exonuclease/phosphatase family protein. (348 aa)
dutPutative dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (144 aa)
KXB83440.1Putative 23S rRNA methyltransferase; KEGG: pdn:HMPREF9137_2384 7.1e-167 PUA domain-containing protein; K06969 23S rRNA (cytosine1962-C5)-methyltransferase; Psort location: Cytoplasmic, score: 9.97. (393 aa)
KXB83332.1MFS transporter, SP family; KEGG: edh:EcDH1_3965 7.6e-115 sugar transporter K08138; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (488 aa)
KXB83356.1Ser/Thr phosphatase family protein; KEGG: bvu:BVU_0146 8.8e-82 5'-nucleotidase; K01081 5'-nucleotidase. (278 aa)
KXB83357.1KEGG: tpi:TREPR_1357 2.6e-24 protein UshA K11751; Belongs to the 5'-nucleotidase family. (336 aa)
tadACytidine and deoxycytidylate deaminase zinc-binding region; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (152 aa)
pyrHUMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (236 aa)
tgttRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...] (375 aa)
KXB83146.1KEGG: eci:UTI89_C3355 1.7e-103 nupG; transport of nucleosides, permease K03289; Psort location: CytoplasmicMembrane, score: 10.00. (414 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (210 aa)
KXB82545.1Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. (376 aa)
KXB82424.1KEGG: pru:PRU_0310 1.7e-110 punA; purine nucleoside phosphorylase I, inosine and guanosine-specific K03783; Psort location: Cytoplasmic, score: 8.96. (255 aa)
surE5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (254 aa)
udkUridine kinase; KEGG: pit:PIN17_A1417 6.6e-93 udk; uridine kinase K00876; Psort location: Cytoplasmic, score: 9.97. (211 aa)
KXB82311.1Hypothetical protein; KEGG: abu:Abu_1717 3.6e-05 hsdM; Type I restriction-modification system, M subunit; Psort location: Cytoplasmic, score: 8.96. (150 aa)
KXB82314.1KEGG: bhl:Bache_2300 2.0e-84 dihydroorotate oxidase B, electron transfer subunit K02823; Psort location: Cytoplasmic, score: 9.26. (258 aa)
pyrDDihydroorotate oxidase, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate. (302 aa)
KXB82235.1Thymidylate synthase ThyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (292 aa)
KXB82251.1Phosphorylase family protein; KEGG: bfr:BF1175 1.1e-117 purine nucleoside phosphorylase II; K00757 uridine phosphorylase; Psort location: Cytoplasmic, score: 9.97. (292 aa)
groSChaperonin GroS; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. (90 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (535 aa)
KXB81472.1KEGG: pit:PIN17_A1313 2.2e-62 cytidine and deoxycytidylate deaminase zinc-binding region; K01493 dCMP deaminase. (145 aa)
KXB80847.1KEGG: pru:PRU_2851 0. nrdD_2; anaerobic ribonucleoside-triphosphate reductase K00527; Psort location: Cytoplasmic, score: 9.97. (740 aa)
KXB80864.1Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (859 aa)
KXB79405.1KEGG: pdn:HMPREF9137_0565 8.6e-226 phosphoribulokinase/uridine kinase family protein; K00876 uridine kinase. (553 aa)
KXB79182.1KEGG: pmz:HMPREF0659_A6372 2.8e-101 putative uracil phosphoribosyltransferase; K00761 uracil phosphoribosyltransferase; Psort location: Cytoplasmic, score: 9.97. (219 aa)
KXB79065.1Dihydroorotase; KEGG: pmz:HMPREF0659_A5999 5.9e-147 amidohydrolase family protein; K01465 dihydroorotase; Psort location: Cytoplasmic, score: 9.97. (443 aa)
tdkThymidine kinase; KEGG: pmz:HMPREF0659_A5428 1.4e-74 tdk; thymidine kinase K00857; Psort location: Cytoplasmic, score: 9.97. (174 aa)
KXB78435.1Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (156 aa)
KXB77863.1Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. (178 aa)
Your Current Organism:
Prevotella sp. DNF00663
NCBI taxonomy Id: 1384078
Other names: P. sp. DNF00663
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