(5 nodes) 6-pyruvoyl tetrahydropterin synthase, and Cell adhesion network (Hymenobacter sp. DG25B)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	queE	7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (207 aa)
	AIZ64406.1	6-pyruvoyl tetrahydrobiopterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (139 aa)
	AIZ64419.1	Alkaline phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa)
	AIZ64564.1	6-pyruvoyl tetrahydrobiopterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (135 aa)
	folE	GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (218 aa)

Your Current Organism:

Hymenobacter sp. DG25B

NCBI taxonomy Id: 1385664
Other names: H. sp. DG25B

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AIZ64406.1	AIZ64419.1	PK28_13280	PK28_13365	6-pyruvoyl tetrahydrobiopterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Alkaline phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.900
AIZ64406.1	AIZ64564.1	PK28_13280	PK28_14380	6-pyruvoyl tetrahydrobiopterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	6-pyruvoyl tetrahydrobiopterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.911
AIZ64406.1	folE	PK28_13280	PK28_14385	6-pyruvoyl tetrahydrobiopterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.961
AIZ64406.1	queE	PK28_13280	PK28_09690	6-pyruvoyl tetrahydrobiopterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.	0.979
AIZ64419.1	AIZ64406.1	PK28_13365	PK28_13280	Alkaline phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.	6-pyruvoyl tetrahydrobiopterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.900
AIZ64419.1	AIZ64564.1	PK28_13365	PK28_14380	Alkaline phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.	6-pyruvoyl tetrahydrobiopterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.900
AIZ64419.1	folE	PK28_13365	PK28_14385	Alkaline phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.	GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.927
AIZ64564.1	AIZ64406.1	PK28_14380	PK28_13280	6-pyruvoyl tetrahydrobiopterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	6-pyruvoyl tetrahydrobiopterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.911
AIZ64564.1	AIZ64419.1	PK28_14380	PK28_13365	6-pyruvoyl tetrahydrobiopterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Alkaline phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.900
AIZ64564.1	folE	PK28_14380	PK28_14385	6-pyruvoyl tetrahydrobiopterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.991
AIZ64564.1	queE	PK28_14380	PK28_09690	6-pyruvoyl tetrahydrobiopterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.	0.979
folE	AIZ64406.1	PK28_14385	PK28_13280	GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	6-pyruvoyl tetrahydrobiopterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.961
folE	AIZ64419.1	PK28_14385	PK28_13365	GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Alkaline phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.927
folE	AIZ64564.1	PK28_14385	PK28_14380	GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	6-pyruvoyl tetrahydrobiopterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.991
folE	queE	PK28_14385	PK28_09690	GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.	0.512
queE	AIZ64406.1	PK28_09690	PK28_13280	7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.	6-pyruvoyl tetrahydrobiopterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.979
queE	AIZ64564.1	PK28_09690	PK28_14380	7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.	6-pyruvoyl tetrahydrobiopterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.979
queE	folE	PK28_09690	PK28_14385	7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.	GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.512