STRINGSTRING
AIZ62483.1 AIZ62483.1 purF purF purD purD purC purC purL purL pyrE pyrE AIZ62488.1 AIZ62488.1 AIZ62489.1 AIZ62489.1 gcvP gcvP aroK aroK AIZ64903.1 AIZ64903.1 rocD rocD AIZ62578.1 AIZ62578.1 AIZ62595.1 AIZ62595.1 AIZ62596.1 AIZ62596.1 AIZ62662.1 AIZ62662.1 trpF trpF glyA glyA AIZ62716.1 AIZ62716.1 AIZ62717.1 AIZ62717.1 AIZ62718.1 AIZ62718.1 ribH ribH coaX coaX glmS glmS panC panC panD panD AIZ62790.1 AIZ62790.1 nusB nusB coaE coaE AIZ62830.1 AIZ62830.1 AIZ62831.1 AIZ62831.1 AIZ64977.1 AIZ64977.1 AIZ63007.1 AIZ63007.1 AIZ63008.1 AIZ63008.1 ppnK ppnK pyrD pyrD AIZ63101.1 AIZ63101.1 purH purH AIZ65004.1 AIZ65004.1 AIZ63217.1 AIZ63217.1 AIZ63245.1 AIZ63245.1 AIZ63247.1 AIZ63247.1 carA carA AIZ63249.1 AIZ63249.1 argC argC AIZ63251.1 AIZ63251.1 AIZ63252.1 AIZ63252.1 argB argB AIZ63254.1 AIZ63254.1 AIZ63255.1 AIZ63255.1 AIZ63258.1 AIZ63258.1 AIZ63259.1 AIZ63259.1 AIZ63260.1 AIZ63260.1 AIZ63280.1 AIZ63280.1 nadE nadE AIZ63317.1 AIZ63317.1 AIZ63318.1 AIZ63318.1 AIZ63323.1 AIZ63323.1 AIZ63353.1 AIZ63353.1 AIZ63368.1 AIZ63368.1 AIZ63369.1 AIZ63369.1 aroA aroA AIZ63395.1 AIZ63395.1 purE purE aspA aspA AIZ63505.1 AIZ63505.1 aroB aroB AIZ63627.1 AIZ63627.1 AIZ63660.1 AIZ63660.1 AIZ63661.1 AIZ63661.1 trpD trpD AIZ63663.1 AIZ63663.1 trpB trpB trpA trpA AIZ63666.1 AIZ63666.1 AIZ63704.1 AIZ63704.1 guaA guaA AIZ65110.1 AIZ65110.1 AIZ63716.1 AIZ63716.1 AIZ63717.1 AIZ63717.1 AIZ65111.1 AIZ65111.1 cobB cobB AIZ63797.1 AIZ63797.1 AIZ65125.1 AIZ65125.1 AIZ63806.1 AIZ63806.1 aroQ aroQ AIZ63822.1 AIZ63822.1 ribBA ribBA dapA dapA folD folD queE queE AIZ63897.1 AIZ63897.1 AIZ63930.1 AIZ63930.1 AIZ63943.1 AIZ63943.1 AIZ63945.1 AIZ63945.1 hisG hisG hisD hisD hisC hisC AIZ63955.1 AIZ63955.1 hisB hisB hisH hisH hisA hisA hisF hisF hisI hisI AIZ63991.1 AIZ63991.1 AIZ64007.1 AIZ64007.1 AIZ64018.1 AIZ64018.1 thyA thyA AIZ64034.1 AIZ64034.1 AIZ64052.1 AIZ64052.1 AIZ64062.1 AIZ64062.1 AIZ64125.1 AIZ64125.1 pyrC pyrC purE-2 purE-2 purK purK carA-2 carA-2 AIZ64214.1 AIZ64214.1 fmt fmt AIZ64231.1 AIZ64231.1 AIZ64300.1 AIZ64300.1 AIZ64301.1 AIZ64301.1 AIZ64302.1 AIZ64302.1 bioD bioD AIZ65219.1 AIZ65219.1 AIZ64310.1 AIZ64310.1 lysA lysA coaD coaD AIZ64323.1 AIZ64323.1 AIZ64324.1 AIZ64324.1 AIZ64389.1 AIZ64389.1 AIZ64394.1 AIZ64394.1 purA purA AIZ64406.1 AIZ64406.1 AIZ64419.1 AIZ64419.1 AIZ64437.1 AIZ64437.1 AIZ64445.1 AIZ64445.1 AIZ64466.1 AIZ64466.1 gcvT gcvT AIZ64515.1 AIZ64515.1 AIZ64516.1 AIZ64516.1 AIZ64531.1 AIZ64531.1 AIZ65260.1 AIZ65260.1 AIZ64546.1 AIZ64546.1 AIZ65263.1 AIZ65263.1 AIZ65264.1 AIZ65264.1 panB panB AIZ64564.1 AIZ64564.1 folE folE AIZ64587.1 AIZ64587.1 AIZ64598.1 AIZ64598.1 AIZ64635.1 AIZ64635.1 aroC aroC guaB guaB dapF dapF nadD nadD ahcY ahcY aroE aroE metK metK asd asd AIZ64816.1 AIZ64816.1 metXA metXA AIZ65309.1 AIZ65309.1 gcvH gcvH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AIZ62483.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (369 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (502 aa)
purDHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GARS family. (421 aa)
purCHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SAICAR synthetase family. (307 aa)
purLPhosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] (1011 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (188 aa)
AIZ62488.1Hypothetical protein; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP). Belongs to the OMP decarboxylase family. Type 2 subfamily. (253 aa)
AIZ62489.1Hypothetical protein; Catalyzes the conversion of dihydroorotate to orotate. (287 aa)
gcvPGlycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (974 aa)
aroKHypothetical protein; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (173 aa)
AIZ64903.1Dihydropteroate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (283 aa)
rocDOrnithine--oxo-acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (400 aa)
AIZ62578.1N-acyl-L-amino acid amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (438 aa)
AIZ62595.1Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1239 aa)
AIZ62596.15,10-methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family. (318 aa)
AIZ62662.1Nicotinate-nucleotide pyrophosphorylase; Catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. (286 aa)
trpFN-(5'-phosphoribosyl)anthranilate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpF family. (224 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (430 aa)
AIZ62716.1Cytochrome C4; Derived by automated computational analysis using gene prediction method: Protein Homology. (357 aa)
AIZ62717.1Prephenate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (281 aa)
AIZ62718.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (397 aa)
ribH6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (158 aa)
coaXHypothetical protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (246 aa)
glmSGlutamine amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (611 aa)
panCPantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (285 aa)
panDAspartate decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (115 aa)
AIZ62790.1Leucine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (363 aa)
nusBNusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (394 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (200 aa)
AIZ62830.1GAF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (160 aa)
AIZ62831.1Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (347 aa)
AIZ64977.1Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. (301 aa)
AIZ63007.1Colicin v production protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (173 aa)
AIZ63008.1Aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (209 aa)
ppnKInorganic polyphosphate kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (298 aa)
pyrDDihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (344 aa)
AIZ63101.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (275 aa)
purHPhosphoribosylaminoimidazolecarboxamide formyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (511 aa)
AIZ65004.1Exopolyphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (347 aa)
AIZ63217.1Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)
AIZ63245.1Acetylornithine carbamoyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (314 aa)
AIZ63247.1Carbamoyl phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (1078 aa)
carACarbamoyl phosphate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family. (361 aa)
AIZ63249.1Acetylornithine aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (387 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (326 aa)
AIZ63251.1Argininosuccinate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (395 aa)
AIZ63252.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (194 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (260 aa)
AIZ63254.1Acetylornithine deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (360 aa)
AIZ63255.1Argininosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (433 aa)
AIZ63258.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (185 aa)
AIZ63259.1LysR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family. (301 aa)
AIZ63260.1Threonine synthase; Catalyzes the formation of L-threonine from O-phospho-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (400 aa)
AIZ63280.1Cystathionine beta-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (373 aa)
nadENAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (644 aa)
AIZ63317.1Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (276 aa)
AIZ63318.1Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (306 aa)
AIZ63323.1Asparagine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (634 aa)
AIZ63353.1Phosphopantothenoylcysteine decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (216 aa)
AIZ63368.1Cytochrome C4; Derived by automated computational analysis using gene prediction method: Protein Homology. (365 aa)
AIZ63369.13-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (347 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (407 aa)
AIZ63395.1Decaheme cytochrome c MtrA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family. (172 aa)
purEN5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (161 aa)
aspAAspartate ammonia-lyase; Catalyzes the formation of fumarate from aspartate; Derived by automated computational analysis using gene prediction method: Protein Homology. (468 aa)
AIZ63505.12-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (161 aa)
aroBCatalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (393 aa)
AIZ63627.11-alkyl-2-acetylglycerophosphocholine esterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (357 aa)
AIZ63660.1Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (471 aa)
AIZ63661.1Anthranilate synthase subunit II; Derived by automated computational analysis using gene prediction method: Protein Homology. (189 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (330 aa)
AIZ63663.1Indole-3-glycerol phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpC family. (270 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (398 aa)
trpATryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (259 aa)
AIZ63666.13-deoxy-7-phosphoheptulonate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa)
AIZ63704.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (237 aa)
guaAGMP synthase; Catalyzes the synthesis of GMP from XMP. (510 aa)
AIZ65110.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family. (481 aa)
AIZ63716.1Sulfate adenylyltransferase; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (425 aa)
AIZ63717.1Sulfate adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa)
AIZ65111.1Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. (247 aa)
cobBNAD-dependent deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sirtuin family. Class III subfamily. (230 aa)
AIZ63797.1Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (433 aa)
AIZ65125.1Malonic semialdehyde reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (252 aa)
AIZ63806.1Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (353 aa)
aroQ3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (148 aa)
AIZ63822.1Damage-inducible protein CinA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family. (426 aa)
ribBA3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (404 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (290 aa)
folD5,10-methylene-tetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (303 aa)
queE7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (207 aa)
AIZ63897.12,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the transferase hexapeptide repeat family. (271 aa)
AIZ63930.18-amino-7-oxononanoate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (412 aa)
AIZ63943.1Dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family. (434 aa)
AIZ63945.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (206 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (283 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (439 aa)
hisCHistidinol phosphate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (350 aa)
AIZ63955.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (139 aa)
hisBImidazoleglycerol-phosphate dehydratase; Catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. (370 aa)
hisHImidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (197 aa)
hisA1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)
hisFImidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (252 aa)
hisIphosphoribosyl-ATP pyrophosphatase; Catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the PRA-CH family. (213 aa)
AIZ63991.1Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. (226 aa)
AIZ64007.1Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (196 aa)
AIZ64018.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (283 aa)
thyAThymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (264 aa)
AIZ64034.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (203 aa)
AIZ64052.1Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (729 aa)
AIZ64062.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (406 aa)
AIZ64125.1Phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (313 aa)
pyrCDihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (425 aa)
purE-2N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (176 aa)
purKPhosphoribosylaminoimidazole carboxylase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (416 aa)
carA-2Carbamoyl phosphate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family. (360 aa)
AIZ64214.1Carbamoyl phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (1078 aa)
fmtmethionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (323 aa)
AIZ64231.1Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (161 aa)
AIZ64300.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (99 aa)
AIZ64301.1Esterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (293 aa)
AIZ64302.18-amino-7-oxononanoate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (378 aa)
bioDATP-dependent dethiobiotin synthetase BioD; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (206 aa)
AIZ65219.1Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (440 aa)
AIZ64310.1Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (445 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (381 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (156 aa)
AIZ64323.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (98 aa)
AIZ64324.1Threonine aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (339 aa)
AIZ64389.1Arginase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the arginase family. (324 aa)
AIZ64394.1Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (454 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (423 aa)
AIZ64406.16-pyruvoyl tetrahydrobiopterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (139 aa)
AIZ64419.1Alkaline phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa)
AIZ64437.13-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (633 aa)
AIZ64445.1Dihydrodipicolinate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DapB family. (239 aa)
AIZ64466.1Riboflavin biosynthesis protein RibF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family. (317 aa)
gcvTGlycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. (368 aa)
AIZ64515.1cob(I)yrinic acid a c-diamide adenosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Cob(I)alamin adenosyltransferase family. (182 aa)
AIZ64516.1Branched-chain amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (354 aa)
AIZ64531.15'-nucleotidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 5'-nucleotidase family. (306 aa)
AIZ65260.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)
AIZ64546.1Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (122 aa)
AIZ65263.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the P-Pant transferase superfamily. (220 aa)
AIZ65264.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (179 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (271 aa)
AIZ64564.16-pyruvoyl tetrahydrobiopterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (135 aa)
folEGTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (218 aa)
AIZ64587.1Isoaspartyl peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (369 aa)
AIZ64598.1Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (379 aa)
AIZ64635.1Deoxyribonucleotide triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (193 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (358 aa)
guaBInosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (490 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (264 aa)
nadDNicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (194 aa)
ahcYAdenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (436 aa)
aroEAroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa)
metKS-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (420 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (331 aa)
AIZ64816.1O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. (460 aa)
metXAHomoserine acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (343 aa)
AIZ65309.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (407 aa)
gcvHGlycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (126 aa)
Your Current Organism:
Hymenobacter sp. DG25B
NCBI taxonomy Id: 1385664
Other names: H. sp. DG25B
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