STRINGSTRING
AKJ08_0154 AKJ08_0154 AKJ08_0266 AKJ08_0266 AKJ08_0466 AKJ08_0466 AKJ08_0469 AKJ08_0469 AKJ08_0904 AKJ08_0904 AKJ08_1057 AKJ08_1057 AKJ08_1231 AKJ08_1231 guaB guaB mdh mdh AKJ08_1405 AKJ08_1405 AKJ08_1487 AKJ08_1487 AKJ08_1625 AKJ08_1625 AKJ08_1631 AKJ08_1631 dxr dxr AKJ08_1882 AKJ08_1882 AKJ08_2044 AKJ08_2044 murB murB AKJ08_2273 AKJ08_2273 AKJ08_2442 AKJ08_2442 AKJ08_2580 AKJ08_2580 AKJ08_2626 AKJ08_2626 gpsA gpsA AKJ08_2751 AKJ08_2751 AKJ08_3012 AKJ08_3012 aroE aroE AKJ08_3179 AKJ08_3179 AKJ08_3223 AKJ08_3223 AKJ08_3241 AKJ08_3241 pdxA pdxA AKJ08_3362 AKJ08_3362 AKJ08_3491 AKJ08_3491 AKJ08_3520 AKJ08_3520
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AKJ08_0154Isocitrate dehydrogenase. (333 aa)
AKJ08_0266D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (528 aa)
AKJ08_04663-hydroxybutyryl-CoA dehydrogenase. (283 aa)
AKJ08_0469NADP-dependent malic enzyme. (761 aa)
AKJ08_0904D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (333 aa)
AKJ08_1057UDP-glucose dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (444 aa)
AKJ08_12313-hydroxybutyryl-CoA dehydrogenase. (284 aa)
guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (516 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (312 aa)
AKJ08_1405Isocitrate dehydrogenase. (419 aa)
AKJ08_1487Short chain dehydrogenase. (238 aa)
AKJ08_1625Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (365 aa)
AKJ08_16313-oxoacyl-[acyl-carrier protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (248 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (393 aa)
AKJ08_18823-isopropylmalate dehydrogenase. (355 aa)
AKJ08_20443,5-diaminohexanoate dehydrogenase. (342 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (305 aa)
AKJ08_2273Alcohol dehydrogenase. (385 aa)
AKJ08_24423-oxoacyl-[acyl-carrier protein] reductase. (245 aa)
AKJ08_2580Alcohol dehydrogenase. (341 aa)
AKJ08_2626UDP-glucose dehydrogenase. (437 aa)
gpsAGlycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (334 aa)
AKJ08_2751Enoyl-CoA hydratase. (731 aa)
AKJ08_3012NAD-dependent malic enzyme. (544 aa)
aroEShikimate 5-dehydrogenase I alpha; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (309 aa)
AKJ08_31792-dehydropantoate 2-reductase. (407 aa)
AKJ08_3223Glucose 1-dehydrogenase. (381 aa)
AKJ08_3241S-(hydroxymethyl)glutathione dehydrogenase. (372 aa)
pdxA4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (332 aa)
AKJ08_3362Aldo-keto reductase. (328 aa)
AKJ08_3491UDP-glucose dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (426 aa)
AKJ08_3520Putative aldo/keto reductase. (327 aa)
Your Current Organism:
Vulgatibacter incomptus
NCBI taxonomy Id: 1391653
Other names: Cystobacteraceae bacterium B00001, DSM 27710, NBRC 109945, V. incomptus, Vulgatibacter incomptus Yamamoto et al. 2014, strain B00001
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.