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| | speA | Biosynthetic arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. (636 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ a [...] (227 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (466 aa) |
| | AKJ08_0065 | Leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (354 aa) |
| | serS | Seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (427 aa) |
| | AKJ08_0093 | Outer membrane protein romA. (348 aa) |
| | panD | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (130 aa) |
| | AKJ08_0130 | Acetyl-coenzyme A carboxyl transferase alpha chain. (530 aa) |
| | AKJ08_0138 | Methylcrotonyl-CoA carboxylase biotin-containing subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (515 aa) |
| | pfkA | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (345 aa) |
| | AKJ08_0154 | Isocitrate dehydrogenase. (333 aa) |
| | AKJ08_0155 | Folate-dependent protein for Fe/S cluster synthesis/repair in oxidative stress; Belongs to the GcvT family. (358 aa) |
| | argD | Acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (398 aa) |
| | AKJ08_0163 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (311 aa) |
| | AKJ08_0191 | Glycine dehydrogenase [decarboxylating] (glycine cleavage system P2 protein). (441 aa) |
| | gcvPA | Glycine dehydrogenase [decarboxylating] (glycine cleavage system P1 protein); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (439 aa) |
| | gcvH | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (131 aa) |
| | gcvT | Aminomethyltransferase (glycine cleavage system T protein); The glycine cleavage system catalyzes the degradation of glycine. (363 aa) |
| | folD | Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (287 aa) |
| | AKJ08_0223 | 2-keto-3-deoxy-D-arabino-heptulosonate-7- phosphate synthase I beta. (350 aa) |
| | AKJ08_0229 | Asparagine synthetase. (646 aa) |
| | AKJ08_0241 | Acyl carrier protein. (80 aa) |
| | AKJ08_0242 | Asparagine synthetase. (658 aa) |
| | accD | Acetyl-coenzyme A carboxyl transferase beta chain; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (259 aa) |
| | AKJ08_0262 | Dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family. (428 aa) |
| | AKJ08_0266 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (528 aa) |
| | serC | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (275 aa) |
| | AKJ08_0268 | Phosphoserine aminotransferase. (96 aa) |
| | aspS | Aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (597 aa) |
| | AKJ08_0294 | Alkyldihydroxyacetonephosphate synthase. (834 aa) |
| | AKJ08_0307 | Fructose-bisphosphate aldolase class I. (308 aa) |
| | AKJ08_0311 | 8-amino-7-oxononanoate synthase. (514 aa) |
| | AKJ08_0329 | Oxidoreductase, FAD-binding. (437 aa) |
| | AKJ08_0356 | Putative deacylase. (456 aa) |
| | AKJ08_0379 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (786 aa) |
| | AKJ08_0380 | NAD-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (420 aa) |
| | AKJ08_0392 | L-asparaginase I, cytoplasmic. (320 aa) |
| | acsA | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (656 aa) |
| | AKJ08_0455 | 3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (399 aa) |
| | AKJ08_0458 | Acyl-CoA hydrolase. (164 aa) |
| | AKJ08_0464 | Alcohol dehydrogenase. (342 aa) |
| | AKJ08_0466 | 3-hydroxybutyryl-CoA dehydrogenase. (283 aa) |
| | plsX | Phosphate:acyl-ACP acyltransferase PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (350 aa) |
| | AKJ08_0523 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (164 aa) |
| | AKJ08_0568 | Rieske 2Fe-2S family protein. (578 aa) |
| | alaS | Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (899 aa) |
| | AKJ08_0622 | Putative racemase. (379 aa) |
| | AKJ08_0624 | Glycolate dehydrogenase. (1024 aa) |
| | AKJ08_0646 | Dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (423 aa) |
| | AKJ08_0713 | Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (189 aa) |
| | AKJ08_0714 | Biotin carboxylase of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (456 aa) |
| | AKJ08_0764 | Mesaconyl-CoA hydratase. (178 aa) |
| | AKJ08_0767 | Monoamine oxidase regulatory-like. (198 aa) |
| | pgi | Glucose-6-phosphate isomerase; Belongs to the GPI family. (457 aa) |
| | pfkA-2 | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (362 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (345 aa) |
| | argJ | Glutamate N-acetyltransferase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (705 aa) |
| | argR | Arginine pathway regulatory protein ArgR, repressor of arg regulon; Regulates arginine biosynthesis genes. (155 aa) |
| | argG | Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (399 aa) |
| | argH | Argininosuccinate lyase. (480 aa) |
| | AKJ08_0834 | Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (696 aa) |
| | pgk | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (394 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (255 aa) |
| | carB | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. (1073 aa) |
| | hutH | Histidine ammonia-lyase. (506 aa) |
| | AKJ08_0893 | Phosphoserine phosphatase. (393 aa) |
| | thrS | Threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (660 aa) |
| | pheS | Phenylalanyl-tRNA synthetase alpha chain; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (391 aa) |
| | pheT | Phenylalanyl-tRNA synthetase beta chain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (797 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (429 aa) |
| | AKJ08_0938 | Aminodeoxychorismate lyase. (241 aa) |
| | asnS | Asparaginyl-tRNA synthetase. (435 aa) |
| | leuS | Leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (826 aa) |
| | lysS | Lysyl-tRNA synthetase (class II); Belongs to the class-II aminoacyl-tRNA synthetase family. (509 aa) |
| | AKJ08_1016 | Benzoyl-CoA oxygenase component B. (470 aa) |
| | AKJ08_1017 | Benzoyl-CoA-dihydrodiol lyase. (546 aa) |
| | glmS | Glucosamine-fructose-6-phosphate aminotransferase, isomerising; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (611 aa) |
| | AKJ08_1053 | Serine acetyltransferase. (171 aa) |
| | AKJ08_1059 | Phosphoglyceromutase. (306 aa) |
| | AKJ08_1061 | Glutamine amidotransferase class-II. (270 aa) |
| | AKJ08_1081 | Iron-sulfur cluster-binding protein, Rieske family. (116 aa) |
| | AKJ08_1096 | Lysine 2,3-aminomutase. (414 aa) |
| | AKJ08_1097 | Lysine 2,3-aminomutase. (435 aa) |
| | ispDF | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). (383 aa) |
| | cysS | Cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (487 aa) |
| | ileS | Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1054 aa) |
| | AKJ08_1204 | 3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa) |
| | AKJ08_1227 | Flagellar basal-body rod modification protein FlgD. (460 aa) |
| | AKJ08_1228 | Hypothetical protein. (447 aa) |
| | AKJ08_1231 | 3-hydroxybutyryl-CoA dehydrogenase. (284 aa) |
| | AKJ08_1240 | Hydroxymethylglutaryl-CoA lyase. (317 aa) |
| | guaA | GMP synthase glutamine-hydrolyzing protein; Catalyzes the synthesis of GMP from XMP. (516 aa) |
| | AKJ08_1329 | Acetyltransferase, GNAT family. (257 aa) |
| | AKJ08_1349 | Methylcrotonyl-CoA carboxylase carboxyl transferase subunit. (531 aa) |
| | tyrS | Tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. (415 aa) |
| | AKJ08_1370 | Glycolate dehydrogenase. (457 aa) |
| | mdh | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (312 aa) |
| | AKJ08_1405 | Isocitrate dehydrogenase. (419 aa) |
| | AKJ08_1407 | Pyruvate kinase; Belongs to the pyruvate kinase family. (466 aa) |
| | carA | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. (373 aa) |
| | pyrB | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (307 aa) |
| | argS | Arginyl-tRNA synthetase. (599 aa) |
| | AKJ08_1454 | MaoC family protein. (213 aa) |
| | AKJ08_1455 | Hypothetical protein. (149 aa) |
| | AKJ08_1456 | Hypothetical protein. (320 aa) |
| | AKJ08_1487 | Short chain dehydrogenase. (238 aa) |
| | gltX | Glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (470 aa) |
| | AKJ08_1580 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (568 aa) |
| | AKJ08_1581 | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (327 aa) |
| | pdhA | Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (338 aa) |
| | AKJ08_1583 | Enoyl-[acyl-carrier-protein] reductase. (272 aa) |
| | AKJ08_1584 | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (260 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (416 aa) |
| | AKJ08_1629 | 3-oxoacyl-[acyl-carrier-protein] synthase, KASII; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (413 aa) |
| | acpP | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (80 aa) |
| | AKJ08_1631 | 3-oxoacyl-[acyl-carrier protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (248 aa) |
| | AKJ08_1632 | Malonyl CoA-acyl carrier protein transacylase. (312 aa) |
| | plsX-2 | Phosphate:acyl-ACP acyltransferase PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (283 aa) |
| | AKJ08_1637 | Hypothetical protein. (373 aa) |
| | AKJ08_1677 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (375 aa) |
| | proS | Prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] (578 aa) |
| | ispG | 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (375 aa) |
| | AKJ08_1731 | Tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (330 aa) |
| | nadA | Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (318 aa) |
| | AKJ08_1744 | Aspartate-semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family. (336 aa) |
| | dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (393 aa) |
| | AKJ08_1756 | Aspartokinase; Belongs to the aspartokinase family. (396 aa) |
| | AKJ08_1783 | Acyl carrier protein. (85 aa) |
| | AKJ08_1843 | Aspartate aminotransferase. (388 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (283 aa) |
| | carB-2 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. (1078 aa) |
| | carA-2 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. (378 aa) |
| | AKJ08_1849 | Threonine dehydrogenase. (757 aa) |
| | AKJ08_1854 | Metal-dependent hydrolase. (258 aa) |
| | AKJ08_1856 | Thiosulfate sulfurtransferase, rhodanese. (274 aa) |
| | AKJ08_1858 | Serine acetyltransferase. (213 aa) |
| | AKJ08_1864 | Threonine dehydratase. (402 aa) |
| | AKJ08_1870 | Zinc-regulated TonB-dependent outer membrane receptor. (478 aa) |
| | AKJ08_1878 | 2-isopropylmalate synthase. (420 aa) |
| | AKJ08_1880 | 3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (404 aa) |
| | AKJ08_1882 | 3-isopropylmalate dehydrogenase. (355 aa) |
| | AKJ08_1884 | 3-isopropylmalate dehydratase large subunit. (655 aa) |
| | AKJ08_1896 | 4-hydroxybutyrate coenzyme A transferase. (423 aa) |
| | AKJ08_1900 | Hydroxyacylglutathione hydrolase. (386 aa) |
| | fabZ | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase, FabZ form; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (146 aa) |
| | AKJ08_1908 | O-succinylbenzoic acid--CoA ligase. (618 aa) |
| | glyS | Glycyl-tRNA synthetase beta chain. (698 aa) |
| | glyQ | Glycyl-tRNA synthetase alpha chain. (298 aa) |
| | ispH | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (302 aa) |
| | hisC | Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (362 aa) |
| | accA | Acetyl-coenzyme A carboxyl transferase alpha chain; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (321 aa) |
| | hisS | Histidyl-tRNA synthetase. (443 aa) |
| | AKJ08_1938 | Aspartate-semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family. (359 aa) |
| | AKJ08_1989 | NAD-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (493 aa) |
| | AKJ08_1997 | Glutamine amidotransferase, class-II. (186 aa) |
| | hutI | Imidazolonepropionase; Belongs to the metallo-dependent hydrolases superfamily. HutI family. (423 aa) |
| | AKJ08_2009 | Cysteine desulfurase. (377 aa) |
| | AKJ08_2010 | Tryptophan 2,3-dioxygenase. (265 aa) |
| | hutU | Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (551 aa) |
| | AKJ08_2017 | Branched-chain amino acid aminotransferase. (354 aa) |
| | AKJ08_2020 | Dihydropteroate synthase. (417 aa) |
| | AKJ08_2025 | 3-keto-5-aminohexanoate cleavage enzyme. (277 aa) |
| | AKJ08_2030 | 3-aminobutyryl-CoA ammonia-lyase. (131 aa) |
| | AKJ08_2044 | 3,5-diaminohexanoate dehydrogenase. (342 aa) |
| | AKJ08_2049 | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (422 aa) |
| | AKJ08_2053 | Radical SAM domain protein. (427 aa) |
| | AKJ08_2054 | Alanine dehydrogenase; Belongs to the AlaDH/PNT family. (376 aa) |
| | valS | Valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (900 aa) |
| | AKJ08_2101 | Hypothetical protein. (406 aa) |
| | AKJ08_2103 | Branched-chain alpha-keto acid dehydrogenase, E1 component, alpha subunit. (335 aa) |
| | AKJ08_2104 | Branched-chain alpha-keto acid dehydrogenase, E1 component, beta subunit. (351 aa) |
| | AKJ08_2117 | Hypothetical protein. (115 aa) |
| | AKJ08_2120 | Branched-chain alpha-keto acid dehydrogenase, E1 component, alpha subunit. (416 aa) |
| | AKJ08_2121 | Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex. (417 aa) |
| | AKJ08_2122 | Branched-chain alpha-keto acid dehydrogenase, E1 component, beta subunit. (327 aa) |
| | lipA | Lipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (324 aa) |
| | AKJ08_2127 | Glycine oxidase ThiO. (367 aa) |
| | AKJ08_2156 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. (166 aa) |
| | AKJ08_2157 | Fumarylacetoacetate hydrolase family protein. (253 aa) |
| | dapB | 4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (269 aa) |
| | dapA | 4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (298 aa) |
| | AKJ08_2169 | Arogenate dehydrogenase. (282 aa) |
| | AKJ08_2180 | Low-specificity L-threonine aldolase. (342 aa) |
| | panB | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (296 aa) |
| | panC | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (337 aa) |
| | AKJ08_2221 | Cystathionine beta-synthase. (324 aa) |
| | AKJ08_2223 | Cystathionine gamma-lyase. (389 aa) |
| | AKJ08_2230 | Translation elongation factor P Lys34:lysine transferase. (348 aa) |
| | AKJ08_2239 | Biotin carboxyl carrier protein. (71 aa) |
| | AKJ08_2274 | Glutamine synthetase family protein. (524 aa) |
| | AKJ08_2275 | GMP synthase. (232 aa) |
| | ispE | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (291 aa) |
| | AKJ08_2390 | Hydrolase, haloacid dehalogenase-like family. (217 aa) |
| | AKJ08_2399 | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. (393 aa) |
| | AKJ08_2414 | 3-oxoacyl-[ACP] synthase III in alkane synthesis cluster. (346 aa) |
| | AKJ08_2442 | 3-oxoacyl-[acyl-carrier protein] reductase. (245 aa) |
| | AKJ08_2449 | Hydroxyacylglutathione hydrolase. (222 aa) |
| | AKJ08_2481 | Methylglyoxal reductase, acetol producing. (285 aa) |
| | glmS-2 | Glucosamine-fructose-6-phosphate aminotransferase, isomerising; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (610 aa) |
| | AKJ08_2550 | Tryptophan 2,3-dioxygenase. (231 aa) |
| | AKJ08_2581 | Lactoylglutathione lyase. (130 aa) |
| | AKJ08_2626 | UDP-glucose dehydrogenase. (437 aa) |
| | AKJ08_2633 | Benzoate-CoA ligase. (516 aa) |
| | AKJ08_2637 | Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (267 aa) |
| | AKJ08_2645 | Cysteine desulfurase. (599 aa) |
| | AKJ08_2654 | Metallo-beta-lactamase family protein. (224 aa) |
| | gpmI | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (518 aa) |
| | AKJ08_2666 | Hydrolase, alpha/beta fold family functionally coupled to Phosphoribulokinase. (293 aa) |
| | bioD | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (242 aa) |
| | bioB | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (336 aa) |
| | dtd | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (149 aa) |
| | AKJ08_2695 | Acetylornithine deacetylase. (459 aa) |
| | AKJ08_2696 | Arginine N-succinyltransferase. (342 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (278 aa) |
| | argC-2 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (350 aa) |
| | AKJ08_2751 | Enoyl-CoA hydratase. (731 aa) |
| | AKJ08_2752 | 3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (432 aa) |
| | AKJ08_2769 | 3-oxoacyl-[acyl-carrier-protein] synthase, KASII; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (522 aa) |
| | AKJ08_2773 | Acyl dehydratase. (153 aa) |
| | AKJ08_2801 | Beta-lactamase domain protein. (293 aa) |
| | AKJ08_2884 | HIT family protein. (140 aa) |
| | AKJ08_2885 | Putative peptidase. (448 aa) |
| | AKJ08_2908 | Methionine gamma-lyase. (394 aa) |
| | kdsA | 2-Keto-3-deoxy-D-manno-octulosonate-8-phosphate synthase; Belongs to the KdsA family. (274 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (560 aa) |
| | prpB | Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. (294 aa) |
| | AKJ08_2992 | 5'-methylthioadenosine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (249 aa) |
| | fumC | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (471 aa) |
| | AKJ08_3012 | NAD-dependent malic enzyme. (544 aa) |
| | AKJ08_3064 | Hypothetical protein. (266 aa) |
| | AKJ08_3089 | Outer membrane protein romA. (393 aa) |
| | AKJ08_3134 | Bifunctional deaminase-reductase domain protein. (206 aa) |
| | AKJ08_3144 | Bifunctional deaminase-reductase domain protein. (104 aa) |
| | AKJ08_3147 | Enoyl-[acyl-carrier-protein] reductase. (182 aa) |
| | AKJ08_3148 | Dihydrofolate reductase. (185 aa) |
| | gluQ | glutamyl-Q-tRNA synthetase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. (311 aa) |
| | AKJ08_3163 | Enoyl-CoA hydratase. (267 aa) |
| | aroA | 5-Enolpyruvylshikimate-3-phosphate synthase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (434 aa) |
| | aroE | Shikimate 5-dehydrogenase I alpha; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (309 aa) |
| | aroK-2 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (572 aa) |
| | aroQ | 3-dehydroquinate dehydratase II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (144 aa) |
| | AKJ08_3179 | 2-dehydropantoate 2-reductase. (407 aa) |
| | ileS-2 | Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (937 aa) |
| | AKJ08_3223 | Glucose 1-dehydrogenase. (381 aa) |
| | AKJ08_3268 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (388 aa) |
| | AKJ08_3324 | Serine acetyltransferase. (322 aa) |
| | AKJ08_3325 | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (318 aa) |
| | AKJ08_3364 | Bifunctional protein: zinc-containing alcohol dehydrogenase. (318 aa) |
| | AKJ08_3445 | Fumarylacetoacetate hydrolase family protein. (324 aa) |
| | AKJ08_3446 | Maleylacetoacetate isomerase. (213 aa) |
| | hmgA | Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. (431 aa) |
| | AKJ08_3448 | 4-hydroxyphenylpyruvate dioxygenase. (352 aa) |
| | AKJ08_3459 | Glutamine synthetase type I. (479 aa) |
| | AKJ08_3503 | Hypothetical protein. (282 aa) |
| | AKJ08_3561 | Beta-lactamase related protein. (309 aa) |
| | AKJ08_3584 | Hypothetical protein. (492 aa) |
| | AKJ08_3632 | Agmatinase; Belongs to the arginase family. (347 aa) |
| | AKJ08_3633 | Amidohydrolase. (461 aa) |
| | AKJ08_3636 | Hypothetical protein. (263 aa) |
| | AKJ08_3645 | Putative oxidoreductase. (184 aa) |
| | AKJ08_3647 | Quinone oxidoreductase. (330 aa) |
