5 items (Sporothrix schenckii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	U7PXK2_SPOS1	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (315 aa)
	U7Q046_SPOS1	CYCLIN domain-containing protein. (447 aa)
	U7Q1F1_SPOS1	CDK-activating kinase assembly factor MAT1. (377 aa)
	U7Q3G0_SPOS1	HTH TFE/IIEalpha-type domain-containing protein. (480 aa)
	U7Q8P7_SPOS1	CMGC/CDK/CDK7 protein kinase; Belongs to the protein kinase superfamily. (437 aa)

Your Current Organism:

Sporothrix schenckii

NCBI taxonomy Id: 1391915
Other names: S. schenckii ATCC 58251, Sporothrix schenckii ATCC 58251

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
U7PXK2_SPOS1	U7Q046_SPOS1	U7PXK2	U7Q046	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.	CYCLIN domain-containing protein.	0.993
U7PXK2_SPOS1	U7Q1F1_SPOS1	U7PXK2	U7Q1F1	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.	CDK-activating kinase assembly factor MAT1.	0.996
U7PXK2_SPOS1	U7Q3G0_SPOS1	U7PXK2	U7Q3G0	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.	HTH TFE/IIEalpha-type domain-containing protein.	0.999
U7PXK2_SPOS1	U7Q8P7_SPOS1	U7PXK2	U7Q8P7	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.	CMGC/CDK/CDK7 protein kinase; Belongs to the protein kinase superfamily.	0.995
U7Q046_SPOS1	U7PXK2_SPOS1	U7Q046	U7PXK2	CYCLIN domain-containing protein.	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.	0.993
U7Q046_SPOS1	U7Q1F1_SPOS1	U7Q046	U7Q1F1	CYCLIN domain-containing protein.	CDK-activating kinase assembly factor MAT1.	0.999
U7Q046_SPOS1	U7Q3G0_SPOS1	U7Q046	U7Q3G0	CYCLIN domain-containing protein.	HTH TFE/IIEalpha-type domain-containing protein.	0.994
U7Q046_SPOS1	U7Q8P7_SPOS1	U7Q046	U7Q8P7	CYCLIN domain-containing protein.	CMGC/CDK/CDK7 protein kinase; Belongs to the protein kinase superfamily.	0.999
U7Q1F1_SPOS1	U7PXK2_SPOS1	U7Q1F1	U7PXK2	CDK-activating kinase assembly factor MAT1.	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.	0.996
U7Q1F1_SPOS1	U7Q046_SPOS1	U7Q1F1	U7Q046	CDK-activating kinase assembly factor MAT1.	CYCLIN domain-containing protein.	0.999
U7Q1F1_SPOS1	U7Q3G0_SPOS1	U7Q1F1	U7Q3G0	CDK-activating kinase assembly factor MAT1.	HTH TFE/IIEalpha-type domain-containing protein.	0.995
U7Q1F1_SPOS1	U7Q8P7_SPOS1	U7Q1F1	U7Q8P7	CDK-activating kinase assembly factor MAT1.	CMGC/CDK/CDK7 protein kinase; Belongs to the protein kinase superfamily.	0.999
U7Q3G0_SPOS1	U7PXK2_SPOS1	U7Q3G0	U7PXK2	HTH TFE/IIEalpha-type domain-containing protein.	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.	0.999
U7Q3G0_SPOS1	U7Q046_SPOS1	U7Q3G0	U7Q046	HTH TFE/IIEalpha-type domain-containing protein.	CYCLIN domain-containing protein.	0.994
U7Q3G0_SPOS1	U7Q1F1_SPOS1	U7Q3G0	U7Q1F1	HTH TFE/IIEalpha-type domain-containing protein.	CDK-activating kinase assembly factor MAT1.	0.995
U7Q3G0_SPOS1	U7Q8P7_SPOS1	U7Q3G0	U7Q8P7	HTH TFE/IIEalpha-type domain-containing protein.	CMGC/CDK/CDK7 protein kinase; Belongs to the protein kinase superfamily.	0.995
U7Q8P7_SPOS1	U7PXK2_SPOS1	U7Q8P7	U7PXK2	CMGC/CDK/CDK7 protein kinase; Belongs to the protein kinase superfamily.	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.	0.995
U7Q8P7_SPOS1	U7Q046_SPOS1	U7Q8P7	U7Q046	CMGC/CDK/CDK7 protein kinase; Belongs to the protein kinase superfamily.	CYCLIN domain-containing protein.	0.999
U7Q8P7_SPOS1	U7Q1F1_SPOS1	U7Q8P7	U7Q1F1	CMGC/CDK/CDK7 protein kinase; Belongs to the protein kinase superfamily.	CDK-activating kinase assembly factor MAT1.	0.999
U7Q8P7_SPOS1	U7Q3G0_SPOS1	U7Q8P7	U7Q3G0	CMGC/CDK/CDK7 protein kinase; Belongs to the protein kinase superfamily.	HTH TFE/IIEalpha-type domain-containing protein.	0.995