10 items (Sporothrix schenckii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	U7Q723_SPOS1	DNA helicase; Belongs to the MCM family. (934 aa)
	U7PHU5_SPOS1	ERCC4 domain-containing protein. (592 aa)
	U7PK89_SPOS1	CDC7 protein kinase. (559 aa)
	MCM7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (835 aa)
	U7PSF8_SPOS1	DNA helicase; Belongs to the MCM family. (886 aa)
	U7PTL2_SPOS1	Uncharacterized protein. (943 aa)
	U7PYU5_SPOS1	DNA helicase; Belongs to the MCM family. (981 aa)
	U7Q0V3_SPOS1	Uncharacterized protein. (478 aa)
	U7Q2I4_SPOS1	DNA helicase; Belongs to the MCM family. (1070 aa)
	U7Q3Z2_SPOS1	DNA helicase; Belongs to the MCM family. (746 aa)

Your Current Organism:

Sporothrix schenckii

NCBI taxonomy Id: 1391915
Other names: S. schenckii ATCC 58251, Sporothrix schenckii ATCC 58251

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MCM7	U7PK89_SPOS1	U7PLF0	U7PK89	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	CDC7 protein kinase.	0.987
MCM7	U7PSF8_SPOS1	U7PLF0	U7PSF8	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	U7PTL2_SPOS1	U7PLF0	U7PTL2	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Uncharacterized protein.	0.999
MCM7	U7PYU5_SPOS1	U7PLF0	U7PYU5	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	U7Q2I4_SPOS1	U7PLF0	U7Q2I4	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	U7Q3Z2_SPOS1	U7PLF0	U7Q3Z2	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	U7Q723_SPOS1	U7PLF0	U7Q723	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
U7PHU5_SPOS1	U7PTL2_SPOS1	U7PHU5	U7PTL2	ERCC4 domain-containing protein.	Uncharacterized protein.	0.507
U7PHU5_SPOS1	U7PYU5_SPOS1	U7PHU5	U7PYU5	ERCC4 domain-containing protein.	DNA helicase; Belongs to the MCM family.	0.443
U7PHU5_SPOS1	U7Q0V3_SPOS1	U7PHU5	U7Q0V3	ERCC4 domain-containing protein.	Uncharacterized protein.	0.738
U7PK89_SPOS1	MCM7	U7PK89	U7PLF0	CDC7 protein kinase.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.987
U7PK89_SPOS1	U7PSF8_SPOS1	U7PK89	U7PSF8	CDC7 protein kinase.	DNA helicase; Belongs to the MCM family.	0.997
U7PK89_SPOS1	U7PTL2_SPOS1	U7PK89	U7PTL2	CDC7 protein kinase.	Uncharacterized protein.	0.904
U7PK89_SPOS1	U7PYU5_SPOS1	U7PK89	U7PYU5	CDC7 protein kinase.	DNA helicase; Belongs to the MCM family.	0.989
U7PK89_SPOS1	U7Q2I4_SPOS1	U7PK89	U7Q2I4	CDC7 protein kinase.	DNA helicase; Belongs to the MCM family.	0.996
U7PK89_SPOS1	U7Q3Z2_SPOS1	U7PK89	U7Q3Z2	CDC7 protein kinase.	DNA helicase; Belongs to the MCM family.	0.991
U7PK89_SPOS1	U7Q723_SPOS1	U7PK89	U7Q723	CDC7 protein kinase.	DNA helicase; Belongs to the MCM family.	0.990
U7PSF8_SPOS1	MCM7	U7PSF8	U7PLF0	DNA helicase; Belongs to the MCM family.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.999
U7PSF8_SPOS1	U7PK89_SPOS1	U7PSF8	U7PK89	DNA helicase; Belongs to the MCM family.	CDC7 protein kinase.	0.997
U7PSF8_SPOS1	U7PTL2_SPOS1	U7PSF8	U7PTL2	DNA helicase; Belongs to the MCM family.	Uncharacterized protein.	0.999