12 items (Sporothrix schenckii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	U7PQ44_SPOS1	PHD-type domain-containing protein. (1076 aa)
	U7PHE8_SPOS1	Uncharacterized protein. (426 aa)
	U7PHM5_SPOS1	AAA_16 domain-containing protein. (508 aa)
	MCM7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (835 aa)
	U7PSF8_SPOS1	DNA helicase; Belongs to the MCM family. (886 aa)
	U7PSI4_SPOS1	ORC_WH_C domain-containing protein. (896 aa)
	U7PUL8_SPOS1	AAA_16 domain-containing protein. (764 aa)
	U7PYU5_SPOS1	DNA helicase; Belongs to the MCM family. (981 aa)
	U7Q2I4_SPOS1	DNA helicase; Belongs to the MCM family. (1070 aa)
	U7Q3Z2_SPOS1	DNA helicase; Belongs to the MCM family. (746 aa)
	U7Q673_SPOS1	Uncharacterized protein. (812 aa)
	U7Q723_SPOS1	DNA helicase; Belongs to the MCM family. (934 aa)

Your Current Organism:

Sporothrix schenckii

NCBI taxonomy Id: 1391915
Other names: S. schenckii ATCC 58251, Sporothrix schenckii ATCC 58251

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MCM7	U7PHE8_SPOS1	U7PLF0	U7PHE8	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Uncharacterized protein.	0.903
MCM7	U7PHM5_SPOS1	U7PLF0	U7PHM5	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	AAA_16 domain-containing protein.	0.988
MCM7	U7PQ44_SPOS1	U7PLF0	U7PQ44	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	PHD-type domain-containing protein.	0.988
MCM7	U7PSF8_SPOS1	U7PLF0	U7PSF8	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	U7PSI4_SPOS1	U7PLF0	U7PSI4	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	ORC_WH_C domain-containing protein.	0.983
MCM7	U7PUL8_SPOS1	U7PLF0	U7PUL8	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	AAA_16 domain-containing protein.	0.999
MCM7	U7PYU5_SPOS1	U7PLF0	U7PYU5	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	U7Q2I4_SPOS1	U7PLF0	U7Q2I4	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	U7Q3Z2_SPOS1	U7PLF0	U7Q3Z2	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	U7Q673_SPOS1	U7PLF0	U7Q673	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Uncharacterized protein.	0.997
MCM7	U7Q723_SPOS1	U7PLF0	U7Q723	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
U7PHE8_SPOS1	MCM7	U7PHE8	U7PLF0	Uncharacterized protein.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.903
U7PHE8_SPOS1	U7PHM5_SPOS1	U7PHE8	U7PHM5	Uncharacterized protein.	AAA_16 domain-containing protein.	0.998
U7PHE8_SPOS1	U7PQ44_SPOS1	U7PHE8	U7PQ44	Uncharacterized protein.	PHD-type domain-containing protein.	0.997
U7PHE8_SPOS1	U7PSF8_SPOS1	U7PHE8	U7PSF8	Uncharacterized protein.	DNA helicase; Belongs to the MCM family.	0.997
U7PHE8_SPOS1	U7PSI4_SPOS1	U7PHE8	U7PSI4	Uncharacterized protein.	ORC_WH_C domain-containing protein.	0.997
U7PHE8_SPOS1	U7PUL8_SPOS1	U7PHE8	U7PUL8	Uncharacterized protein.	AAA_16 domain-containing protein.	0.997
U7PHE8_SPOS1	U7PYU5_SPOS1	U7PHE8	U7PYU5	Uncharacterized protein.	DNA helicase; Belongs to the MCM family.	0.918
U7PHE8_SPOS1	U7Q2I4_SPOS1	U7PHE8	U7Q2I4	Uncharacterized protein.	DNA helicase; Belongs to the MCM family.	0.914
U7PHE8_SPOS1	U7Q3Z2_SPOS1	U7PHE8	U7Q3Z2	Uncharacterized protein.	DNA helicase; Belongs to the MCM family.	0.940