STRINGSTRING
U7Q4V3_SPOS1 U7Q4V3_SPOS1 U7PHE8_SPOS1 U7PHE8_SPOS1 U7PHM5_SPOS1 U7PHM5_SPOS1 U7PHS0_SPOS1 U7PHS0_SPOS1 U7PJ99_SPOS1 U7PJ99_SPOS1 U7PJD3_SPOS1 U7PJD3_SPOS1 U7PJZ1_SPOS1 U7PJZ1_SPOS1 U7PK33_SPOS1 U7PK33_SPOS1 SLX4 SLX4 U7PK61_SPOS1 U7PK61_SPOS1 U7PK89_SPOS1 U7PK89_SPOS1 U7PKR8_SPOS1 U7PKR8_SPOS1 U7PKY9_SPOS1 U7PKY9_SPOS1 MCM7 MCM7 U7PM20_SPOS1 U7PM20_SPOS1 U7PMA4_SPOS1 U7PMA4_SPOS1 U7PMR1_SPOS1 U7PMR1_SPOS1 U7PN36_SPOS1 U7PN36_SPOS1 U7PN96_SPOS1 U7PN96_SPOS1 U7PNQ6_SPOS1 U7PNQ6_SPOS1 U7PPA9_SPOS1 U7PPA9_SPOS1 U7PPQ6_SPOS1 U7PPQ6_SPOS1 U7PQ44_SPOS1 U7PQ44_SPOS1 U7PQA3_SPOS1 U7PQA3_SPOS1 U7PQC1_SPOS1 U7PQC1_SPOS1 U7PQL3_SPOS1 U7PQL3_SPOS1 U7PQP1_SPOS1 U7PQP1_SPOS1 U7PR10_SPOS1 U7PR10_SPOS1 U7PR88_SPOS1 U7PR88_SPOS1 U7PRD3_SPOS1 U7PRD3_SPOS1 U7PRM5_SPOS1 U7PRM5_SPOS1 U7PS96_SPOS1 U7PS96_SPOS1 U7PSC7_SPOS1 U7PSC7_SPOS1 U7PSF8_SPOS1 U7PSF8_SPOS1 U7PSI4_SPOS1 U7PSI4_SPOS1 U7PSI6_SPOS1 U7PSI6_SPOS1 U7PSJ8_SPOS1 U7PSJ8_SPOS1 U7PSN9_SPOS1 U7PSN9_SPOS1 U7PSQ1_SPOS1 U7PSQ1_SPOS1 U7PSU2_SPOS1 U7PSU2_SPOS1 U7PSZ7_SPOS1 U7PSZ7_SPOS1 U7PT11_SPOS1 U7PT11_SPOS1 U7PTD5_SPOS1 U7PTD5_SPOS1 U7PTE2_SPOS1 U7PTE2_SPOS1 FEN1 FEN1 U7PTL2_SPOS1 U7PTL2_SPOS1 U7PTX1_SPOS1 U7PTX1_SPOS1 U7PU04_SPOS1 U7PU04_SPOS1 U7PU71_SPOS1 U7PU71_SPOS1 U7PUJ4_SPOS1 U7PUJ4_SPOS1 U7PUK1_SPOS1 U7PUK1_SPOS1 U7PUL8_SPOS1 U7PUL8_SPOS1 U7PV00_SPOS1 U7PV00_SPOS1 U7PVW6_SPOS1 U7PVW6_SPOS1 U7PW76_SPOS1 U7PW76_SPOS1 U7PWB6_SPOS1 U7PWB6_SPOS1 U7PWN1_SPOS1 U7PWN1_SPOS1 U7PWT7_SPOS1 U7PWT7_SPOS1 U7PY10_SPOS1 U7PY10_SPOS1 U7PYP9_SPOS1 U7PYP9_SPOS1 U7PYT6_SPOS1 U7PYT6_SPOS1 U7PYU5_SPOS1 U7PYU5_SPOS1 U7PZA2_SPOS1 U7PZA2_SPOS1 U7PZR6_SPOS1 U7PZR6_SPOS1 U7Q001_SPOS1 U7Q001_SPOS1 U7Q071_SPOS1 U7Q071_SPOS1 U7Q0B7_SPOS1 U7Q0B7_SPOS1 U7Q0Q8_SPOS1 U7Q0Q8_SPOS1 U7Q0V3_SPOS1 U7Q0V3_SPOS1 U7Q134_SPOS1 U7Q134_SPOS1 U7Q289_SPOS1 U7Q289_SPOS1 U7Q2H2_SPOS1 U7Q2H2_SPOS1 U7Q2I4_SPOS1 U7Q2I4_SPOS1 U7Q3D4_SPOS1 U7Q3D4_SPOS1 U7Q3G3_SPOS1 U7Q3G3_SPOS1 U7Q3W4_SPOS1 U7Q3W4_SPOS1 U7Q3Z2_SPOS1 U7Q3Z2_SPOS1 U7Q447_SPOS1 U7Q447_SPOS1 U7Q4H2_SPOS1 U7Q4H2_SPOS1 U7Q4K5_SPOS1 U7Q4K5_SPOS1 U7Q4T5_SPOS1 U7Q4T5_SPOS1 U7Q4V5_SPOS1 U7Q4V5_SPOS1 U7Q576_SPOS1 U7Q576_SPOS1 U7Q5E2_SPOS1 U7Q5E2_SPOS1 U7Q5L8_SPOS1 U7Q5L8_SPOS1 U7Q5N1_SPOS1 U7Q5N1_SPOS1 U7Q5S6_SPOS1 U7Q5S6_SPOS1 U7Q673_SPOS1 U7Q673_SPOS1 U7Q6L6_SPOS1 U7Q6L6_SPOS1 U7Q6M0_SPOS1 U7Q6M0_SPOS1 U7Q6U9_SPOS1 U7Q6U9_SPOS1 U7Q723_SPOS1 U7Q723_SPOS1 U7Q781_SPOS1 U7Q781_SPOS1 U7Q7S5_SPOS1 U7Q7S5_SPOS1 U7Q874_SPOS1 U7Q874_SPOS1 U7Q8D4_SPOS1 U7Q8D4_SPOS1 U7Q8H5_SPOS1 U7Q8H5_SPOS1 U7Q914_SPOS1 U7Q914_SPOS1 U7Q9L5_SPOS1 U7Q9L5_SPOS1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
U7Q4V3_SPOS1Sld5 domain-containing protein. (240 aa)
U7PHE8_SPOS1Uncharacterized protein. (426 aa)
U7PHM5_SPOS1AAA_16 domain-containing protein. (508 aa)
U7PHS0_SPOS1CBFD_NFYB_HMF domain-containing protein. (248 aa)
U7PJ99_SPOS1Uncharacterized protein. (680 aa)
U7PJD3_SPOS1Uncharacterized protein. (918 aa)
U7PJZ1_SPOS1Uncharacterized protein. (429 aa)
U7PK33_SPOS1DNA_pol_E_B domain-containing protein. (960 aa)
SLX4Structure-specific endonuclease subunit SLX4; Regulatory subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (907 aa)
U7PK61_SPOS1MRC1 domain-containing protein. (1614 aa)
U7PK89_SPOS1CDC7 protein kinase. (559 aa)
U7PKR8_SPOS1ERCC4 domain-containing protein. (876 aa)
U7PKY9_SPOS1Uncharacterized protein. (477 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (835 aa)
U7PM20_SPOS1Replication factor C subunit 4. (359 aa)
U7PMA4_SPOS1CAMK protein kinase. (1448 aa)
U7PMR1_SPOS1DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (353 aa)
U7PN36_SPOS1Replication factor C subunit 1. (1117 aa)
U7PN96_SPOS1DNA ligase. (874 aa)
U7PNQ6_SPOS1Replication factor C subunit 5. (352 aa)
U7PPA9_SPOS1Uncharacterized protein. (215 aa)
U7PPQ6_SPOS1Uncharacterized protein. (657 aa)
U7PQ44_SPOS1PHD-type domain-containing protein. (1076 aa)
U7PQA3_SPOS1DNA polymerase. (1545 aa)
U7PQC1_SPOS1DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1242 aa)
U7PQL3_SPOS1CAMK protein kinase. (1027 aa)
U7PQP1_SPOS1Zf-primase domain-containing protein. (872 aa)
U7PR10_SPOS1Uncharacterized protein. (140 aa)
U7PR88_SPOS1Ribonucleoside-diphosphate reductase small chain. (404 aa)
U7PRD3_SPOS1CAMK protein kinase. (709 aa)
U7PRM5_SPOS1DNA polymerase. (1652 aa)
U7PS96_SPOS1SLD3 domain-containing protein. (1115 aa)
U7PSC7_SPOS1PUL domain-containing protein. (482 aa)
U7PSF8_SPOS1DNA helicase; Belongs to the MCM family. (886 aa)
U7PSI4_SPOS1ORC_WH_C domain-containing protein. (896 aa)
U7PSI6_SPOS1Helicase C-terminal domain-containing protein. (743 aa)
U7PSJ8_SPOS1Uncharacterized protein. (981 aa)
U7PSN9_SPOS1AAA domain-containing protein. (414 aa)
U7PSQ1_SPOS1RRM domain-containing protein. (358 aa)
U7PSU2_SPOS1DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (696 aa)
U7PSZ7_SPOS1Uncharacterized protein. (1800 aa)
U7PT11_SPOS1Uncharacterized protein. (1088 aa)
U7PTD5_SPOS1Uncharacterized protein. (286 aa)
U7PTE2_SPOS1DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (221 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (395 aa)
U7PTL2_SPOS1Uncharacterized protein. (943 aa)
U7PTX1_SPOS1CBFD_NFYB_HMF domain-containing protein. (299 aa)
U7PU04_SPOS1HD domain-containing protein. (279 aa)
U7PU71_SPOS1BAH domain-containing protein. (774 aa)
U7PUJ4_SPOS1Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (935 aa)
U7PUK1_SPOS1Uncharacterized protein. (107 aa)
U7PUL8_SPOS1AAA_16 domain-containing protein. (764 aa)
U7PV00_SPOS1AAA domain-containing protein. (1456 aa)
U7PVW6_SPOS1Nuclear protein localization protein 4. (719 aa)
U7PW76_SPOS1DNA polymerase. (1115 aa)
U7PWB6_SPOS1WD_REPEATS_REGION domain-containing protein. (834 aa)
U7PWN1_SPOS1DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2402 aa)
U7PWT7_SPOS1Uncharacterized protein. (521 aa)
U7PY10_SPOS1DNA_LIGASE_A3 domain-containing protein. (1021 aa)
U7PYP9_SPOS1UmuC domain-containing protein. (671 aa)
U7PYT6_SPOS1DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (669 aa)
U7PYU5_SPOS1DNA helicase; Belongs to the MCM family. (981 aa)
U7PZA2_SPOS1Uncharacterized protein. (374 aa)
U7PZR6_SPOS1Rtf2 domain-containing protein. (318 aa)
U7Q001_SPOS1RNase H domain-containing protein. (394 aa)
U7Q071_SPOS1WD_REPEATS_REGION domain-containing protein. (926 aa)
U7Q0B7_SPOS1Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (392 aa)
U7Q0Q8_SPOS1FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (572 aa)
U7Q0V3_SPOS1Uncharacterized protein. (478 aa)
U7Q134_SPOS1DNA ligase. (917 aa)
U7Q289_SPOS1POLAc domain-containing protein. (1193 aa)
U7Q2H2_SPOS1Uncharacterized protein. (115 aa)
U7Q2I4_SPOS1DNA helicase; Belongs to the MCM family. (1070 aa)
U7Q3D4_SPOS1Nucleolar complex-associated protein 3; Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm. Belongs to the CBF/MAK21 family. (729 aa)
U7Q3G3_SPOS1Pre-mRNA-splicing factor clf-1. (707 aa)
U7Q3W4_SPOS1AAA domain-containing protein. (1114 aa)
U7Q3Z2_SPOS1DNA helicase; Belongs to the MCM family. (746 aa)
U7Q447_SPOS1Uncharacterized protein. (187 aa)
U7Q4H2_SPOS1Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (628 aa)
U7Q4K5_SPOS1DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (468 aa)
U7Q4T5_SPOS1FACT complex subunit spt-16. (1033 aa)
U7Q4V5_SPOS1Uncharacterized protein. (548 aa)
U7Q576_SPOS1AAA domain-containing protein. (412 aa)
U7Q5E2_SPOS1Vezatin domain-containing protein. (694 aa)
U7Q5L8_SPOS1RING-type domain-containing protein. (429 aa)
U7Q5N1_SPOS1Uncharacterized protein. (1227 aa)
U7Q5S6_SPOS1Uncharacterized protein. (138 aa)
U7Q673_SPOS1Uncharacterized protein. (812 aa)
U7Q6L6_SPOS1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (589 aa)
U7Q6M0_SPOS1Uncharacterized protein. (637 aa)
U7Q6U9_SPOS1Uncharacterized protein. (504 aa)
U7Q723_SPOS1DNA helicase; Belongs to the MCM family. (934 aa)
U7Q781_SPOS1Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (259 aa)
U7Q7S5_SPOS1DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (894 aa)
U7Q874_SPOS1Zn(2)-C6 fungal-type domain-containing protein. (1076 aa)
U7Q8D4_SPOS1D-aminoacyl-tRNA deacylase. (164 aa)
U7Q8H5_SPOS1Sld5 domain-containing protein. (232 aa)
U7Q914_SPOS1Sld5 domain-containing protein. (334 aa)
U7Q9L5_SPOS1Uncharacterized protein. (169 aa)
Your Current Organism:
Sporothrix schenckii
NCBI taxonomy Id: 1391915
Other names: S. schenckii ATCC 58251, Sporothrix schenckii ATCC 58251
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