STRINGSTRING
U7PHE1_SPOS1 U7PHE1_SPOS1 U7PQJ9_SPOS1 U7PQJ9_SPOS1 U7PQP4_SPOS1 U7PQP4_SPOS1 U7PQX9_SPOS1 U7PQX9_SPOS1 MDE1 MDE1 U7PR09_SPOS1 U7PR09_SPOS1 U7PR65_SPOS1 U7PR65_SPOS1 U7PRA4_SPOS1 U7PRA4_SPOS1 U7PRB6_SPOS1 U7PRB6_SPOS1 U7PRM7_SPOS1 U7PRM7_SPOS1 U7PRR2_SPOS1 U7PRR2_SPOS1 U7PSD6_SPOS1 U7PSD6_SPOS1 U7PSP2_SPOS1 U7PSP2_SPOS1 U7PSP4_SPOS1 U7PSP4_SPOS1 U7PSQ6_SPOS1 U7PSQ6_SPOS1 U7PSS7_SPOS1 U7PSS7_SPOS1 U7PSU1_SPOS1 U7PSU1_SPOS1 U7PT00_SPOS1 U7PT00_SPOS1 U7PT05_SPOS1 U7PT05_SPOS1 MET3 MET3 U7PTJ3_SPOS1 U7PTJ3_SPOS1 U7PTT4_SPOS1 U7PTT4_SPOS1 U7PU58_SPOS1 U7PU58_SPOS1 U7PU67_SPOS1 U7PU67_SPOS1 U7PU87_SPOS1 U7PU87_SPOS1 U7PU91_SPOS1 U7PU91_SPOS1 U7PUV5_SPOS1 U7PUV5_SPOS1 U7PUX3_SPOS1 U7PUX3_SPOS1 U7PV35_SPOS1 U7PV35_SPOS1 U7PV48_SPOS1 U7PV48_SPOS1 U7PVK0_SPOS1 U7PVK0_SPOS1 U7PVR4_SPOS1 U7PVR4_SPOS1 U7PWC7_SPOS1 U7PWC7_SPOS1 U7PWD4_SPOS1 U7PWD4_SPOS1 U7PWM2_SPOS1 U7PWM2_SPOS1 U7PWR3_SPOS1 U7PWR3_SPOS1 U7PWZ9_SPOS1 U7PWZ9_SPOS1 U7PXD9_SPOS1 U7PXD9_SPOS1 U7PXX1_SPOS1 U7PXX1_SPOS1 U7PYC2_SPOS1 U7PYC2_SPOS1 U7PYG1_SPOS1 U7PYG1_SPOS1 U7PYH1_SPOS1 U7PYH1_SPOS1 U7PYL5_SPOS1 U7PYL5_SPOS1 U7PYX3_SPOS1 U7PYX3_SPOS1 U7PZ19_SPOS1 U7PZ19_SPOS1 U7PZ20_SPOS1 U7PZ20_SPOS1 U7PZT5_SPOS1 U7PZT5_SPOS1 U7Q007_SPOS1 U7Q007_SPOS1 U7Q0C9_SPOS1 U7Q0C9_SPOS1 U7Q0I5_SPOS1 U7Q0I5_SPOS1 U7Q0Q9_SPOS1 U7Q0Q9_SPOS1 U7Q0Z6_SPOS1 U7Q0Z6_SPOS1 U7Q124_SPOS1 U7Q124_SPOS1 U7Q167_SPOS1 U7Q167_SPOS1 U7Q179_SPOS1 U7Q179_SPOS1 U7Q1U3_SPOS1 U7Q1U3_SPOS1 U7Q280_SPOS1 U7Q280_SPOS1 U7Q295_SPOS1 U7Q295_SPOS1 U7Q2G8_SPOS1 U7Q2G8_SPOS1 U7Q2L8_SPOS1 U7Q2L8_SPOS1 U7Q2M4_SPOS1 U7Q2M4_SPOS1 U7Q2T0_SPOS1 U7Q2T0_SPOS1 U7Q351_SPOS1 U7Q351_SPOS1 U7Q3E6_SPOS1 U7Q3E6_SPOS1 U7Q3K7_SPOS1 U7Q3K7_SPOS1 U7Q412_SPOS1 U7Q412_SPOS1 U7Q484_SPOS1 U7Q484_SPOS1 U7Q4C1_SPOS1 U7Q4C1_SPOS1 U7Q4L7_SPOS1 U7Q4L7_SPOS1 U7Q562_SPOS1 U7Q562_SPOS1 U7Q5A4_SPOS1 U7Q5A4_SPOS1 U7Q6C9_SPOS1 U7Q6C9_SPOS1 U7Q6E6_SPOS1 U7Q6E6_SPOS1 U7Q6Q5_SPOS1 U7Q6Q5_SPOS1 U7Q6T6_SPOS1 U7Q6T6_SPOS1 U7Q6Y1_SPOS1 U7Q6Y1_SPOS1 U7Q706_SPOS1 U7Q706_SPOS1 U7Q767_SPOS1 U7Q767_SPOS1 U7Q862_SPOS1 U7Q862_SPOS1 U7PH29_SPOS1 U7PH29_SPOS1 U7PHF3_SPOS1 U7PHF3_SPOS1 U7PHP6_SPOS1 U7PHP6_SPOS1 U7PI31_SPOS1 U7PI31_SPOS1 U7PIZ2_SPOS1 U7PIZ2_SPOS1 U7PJ15_SPOS1 U7PJ15_SPOS1 U7PJL6_SPOS1 U7PJL6_SPOS1 U7PJP6_SPOS1 U7PJP6_SPOS1 U7PJX2_SPOS1 U7PJX2_SPOS1 U7PJZ7_SPOS1 U7PJZ7_SPOS1 U7PK40_SPOS1 U7PK40_SPOS1 U7PKC2_SPOS1 U7PKC2_SPOS1 U7PKN1_SPOS1 U7PKN1_SPOS1 U7PKS3_SPOS1 U7PKS3_SPOS1 U7PL12_SPOS1 U7PL12_SPOS1 U7PL13_SPOS1 U7PL13_SPOS1 U7PL50_SPOS1 U7PL50_SPOS1 MRI1 MRI1 U7PLA0_SPOS1 U7PLA0_SPOS1 U7PLH0_SPOS1 U7PLH0_SPOS1 U7PLN5_SPOS1 U7PLN5_SPOS1 U7PLZ0_SPOS1 U7PLZ0_SPOS1 U7PM83_SPOS1 U7PM83_SPOS1 U7PMI3_SPOS1 U7PMI3_SPOS1 U7PMM8_SPOS1 U7PMM8_SPOS1 U7PMU0_SPOS1 U7PMU0_SPOS1 U7PMU9_SPOS1 U7PMU9_SPOS1 U7PMW9_SPOS1 U7PMW9_SPOS1 U7PN54_SPOS1 U7PN54_SPOS1 U7PN76_SPOS1 U7PN76_SPOS1 U7PNA0_SPOS1 U7PNA0_SPOS1 U7PNF3_SPOS1 U7PNF3_SPOS1 U7PP13_SPOS1 U7PP13_SPOS1 U7PPA3_SPOS1 U7PPA3_SPOS1 U7PPG0_SPOS1 U7PPG0_SPOS1 U7PPI0_SPOS1 U7PPI0_SPOS1 U7PPI7_SPOS1 U7PPI7_SPOS1 U7PPS7_SPOS1 U7PPS7_SPOS1 U7PPT1_SPOS1 U7PPT1_SPOS1 U7PPT2_SPOS1 U7PPT2_SPOS1 U7PPX0_SPOS1 U7PPX0_SPOS1 U7PQ42_SPOS1 U7PQ42_SPOS1 ADI1 ADI1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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U7PHE1_SPOS1Acetolactate synthase, small subunit. (330 aa)
U7PQJ9_SPOS13-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (370 aa)
U7PQP4_SPOS1Phospho-2-dehydro-3-deoxyheptonate aldolase. (372 aa)
U7PQX9_SPOS12,3-diketo-5-methylthio-1-phosphopentane phosphatase. (227 aa)
MDE1Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). (275 aa)
U7PR09_SPOS1Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. (315 aa)
U7PR65_SPOS1Dihydroxy-acid dehydratase. (665 aa)
U7PRA4_SPOS1Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities. (790 aa)
U7PRB6_SPOS1Uncharacterized protein. (340 aa)
U7PRM7_SPOS1Uncharacterized protein. (268 aa)
U7PRR2_SPOS1Argininosuccinate lyase. (465 aa)
U7PSD6_SPOS1Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (426 aa)
U7PSP2_SPOS1ATP phosphoribosyltransferase. (347 aa)
U7PSP4_SPOS1Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (541 aa)
U7PSQ6_SPOS1Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (628 aa)
U7PSS7_SPOS1Beta_elim_lyase domain-containing protein. (384 aa)
U7PSU1_SPOS1Dihydroxy-acid dehydratase. (636 aa)
U7PT00_SPOS1Uncharacterized protein. (336 aa)
U7PT05_SPOS1Uncharacterized protein. (760 aa)
MET3Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. In the N-terminal section; belongs to the sulfate adenylyltransferase family. (573 aa)
U7PTJ3_SPOS1Saccharopine dehydrogenase [NAD(+), L-lysine-forming]; Belongs to the AlaDH/PNT family. (374 aa)
U7PTT4_SPOS1Peptidase_M24 domain-containing protein. (504 aa)
U7PU58_SPOS1Homoserine dehydrogenase. (367 aa)
U7PU67_SPOS1Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. (786 aa)
U7PU87_SPOS1Threonine dehydratase. (608 aa)
U7PU91_SPOS12-isopropylmalate synthase. (632 aa)
U7PUV5_SPOS1Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (456 aa)
U7PUX3_SPOS1APH domain-containing protein. (189 aa)
U7PV35_SPOS1Carbamoyl-phosphate synthase, large subunit. (1183 aa)
U7PV48_SPOS1Zn(2)-C6 fungal-type domain-containing protein. (837 aa)
U7PVK0_SPOS13-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (783 aa)
U7PVR4_SPOS1Iso_dh domain-containing protein. (369 aa)
U7PWC7_SPOS1Phosphoglycerate dehydrogenase. (641 aa)
U7PWD4_SPOS15-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase. (767 aa)
U7PWM2_SPOS1N-acetyl-gamma-glutamyl-phosphate reductase; In the N-terminal section; belongs to the acetylglutamate kinase family. (946 aa)
U7PWR3_SPOS1ACPS domain-containing protein. (303 aa)
U7PWZ9_SPOS1Uncharacterized protein. (549 aa)
U7PXD9_SPOS1Phosphoserine phosphatase SerB. (214 aa)
U7PXX1_SPOS1Phosphoadenosine phosphosulfate reductase. (336 aa)
U7PYC2_SPOS1Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (286 aa)
U7PYG1_SPOS1Saccharopine dehydrogenase [NADP+, L-glutamate-forming]. (448 aa)
U7PYH1_SPOS1Glutamine synthetase. (392 aa)
U7PYL5_SPOS1Glutamine amidotransferase type-2 domain-containing protein. (2113 aa)
U7PYX3_SPOS1Cysteine synthase. (393 aa)
U7PZ19_SPOS1Aspartate aminotransferase. (425 aa)
U7PZ20_SPOS1Uncharacterized protein. (320 aa)
U7PZT5_SPOS1Argininosuccinate synthase. (416 aa)
U7Q007_SPOS1Prephenate/arogenate dehydrogenase domain-containing protein. (387 aa)
U7Q0C9_SPOS1Meth_synt_2 domain-containing protein. (402 aa)
U7Q0I5_SPOS1Uncharacterized protein. (618 aa)
U7Q0Q9_SPOS1Dihydroxy-acid dehydratase. (604 aa)
U7Q0Z6_SPOS11-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (303 aa)
U7Q124_SPOS1PALP domain-containing protein. (406 aa)
U7Q167_SPOS1Glutamate 5-kinase. (498 aa)
U7Q179_SPOS1Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. (558 aa)
U7Q1U3_SPOS1Phospho-2-dehydro-3-deoxyheptonate aldolase. (378 aa)
U7Q280_SPOS1S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (311 aa)
U7Q295_SPOS1Aspartate aminotransferase. (421 aa)
U7Q2G8_SPOS1Aminotran_1_2 domain-containing protein. (709 aa)
U7Q2L8_SPOS1Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (706 aa)
U7Q2M4_SPOS1APH domain-containing protein. (336 aa)
U7Q2T0_SPOS1PALP domain-containing protein. (540 aa)
U7Q351_SPOS1Glutamate-5-semialdehyde dehydrogenase. (457 aa)
U7Q3E6_SPOS1DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (223 aa)
U7Q3K7_SPOS1Ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family. (404 aa)
U7Q412_SPOS1Anthranilate phosphoribosyltransferase. (435 aa)
U7Q484_SPOS1Uncharacterized protein. (247 aa)
U7Q4C1_SPOS1Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (479 aa)
U7Q4L7_SPOS1Aminotran_1_2 domain-containing protein. (599 aa)
U7Q562_SPOS1Asparagine synthase (Glutamine-hydrolyzing). (575 aa)
U7Q5A4_SPOS1Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (524 aa)
U7Q6C9_SPOS1Histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. (345 aa)
U7Q6E6_SPOS1FAD-binding FR-type domain-containing protein. (706 aa)
U7Q6Q5_SPOS1Aspartokinase. (546 aa)
U7Q6T6_SPOS1Uncharacterized protein. (682 aa)
U7Q6Y1_SPOS1Cystathionine beta-lyase. (434 aa)
U7Q706_SPOS1Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (426 aa)
U7Q767_SPOS1Homoserine kinase. (355 aa)
U7Q862_SPOS1HET domain-containing protein. (771 aa)
U7PH29_SPOS1Uncharacterized protein. (251 aa)
U7PHF3_SPOS13-phosphoshikimate 1-carboxyvinyltransferase; The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis. In the 2nd section; belongs to the EPSP synthase family. In the 4th section; belongs to the type-I 3-dehydroquinase family. In the N-terminal section; belongs to the dehydroquinate synthase family. (1544 aa)
U7PHP6_SPOS1Meth_synt_2 domain-containing protein. (401 aa)
U7PI31_SPOS1Zn(2)-C6 fungal-type domain-containing protein. (826 aa)
U7PIZ2_SPOS1Glutamine amidotransferase type-1 domain-containing protein. (941 aa)
U7PJ15_SPOS1Uncharacterized protein. (156 aa)
U7PJL6_SPOS1Uncharacterized protein. (280 aa)
U7PJP6_SPOS1Arginine biosynthesis bifunctional protein ArgJ, mitochondrial; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate; Belongs to the ArgJ family. (489 aa)
U7PJX2_SPOS1Acetolactate synthase. (696 aa)
U7PJZ7_SPOS1Amino-acid acetyltransferase, mitochondrial; N-acetylglutamate synthase involved in arginine biosynthesis. Belongs to the acetyltransferase family. (740 aa)
U7PK40_SPOS1Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (359 aa)
U7PKC2_SPOS1Uncharacterized protein. (470 aa)
U7PKN1_SPOS1Histidinol-phosphate transaminase. (411 aa)
U7PKS3_SPOS13-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (378 aa)
U7PL12_SPOS1Glutamine amidotransferase type-2 domain-containing protein. (612 aa)
U7PL13_SPOS1Uncharacterized protein. (546 aa)
U7PL50_SPOS1Uncharacterized protein. (579 aa)
MRI1Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. (394 aa)
U7PLA0_SPOS1Threonine synthase. (558 aa)
U7PLH0_SPOS1Imidazoleglycerol-phosphate dehydratase; Belongs to the imidazoleglycerol-phosphate dehydratase family. (234 aa)
U7PLN5_SPOS1Uncharacterized protein. (467 aa)
U7PLZ0_SPOS1Histidine biosynthesis trifunctional protein. (873 aa)
U7PM83_SPOS1Phosphoserine transaminase; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. (437 aa)
U7PMI3_SPOS1Ornithine aminotransferase. (446 aa)
U7PMM8_SPOS1Amidase domain-containing protein. (571 aa)
U7PMU0_SPOS1Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (476 aa)
U7PMU9_SPOS1Homocitrate synthase, mitochondrial; Belongs to the alpha-IPM synthase/homocitrate synthase family. (450 aa)
U7PMW9_SPOS1Chorismate synthase. (425 aa)
U7PN54_SPOS1Zn(2)-C6 fungal-type domain-containing protein. (518 aa)
U7PN76_SPOS1Protein pyrABCN. (2361 aa)
U7PNA0_SPOS1Pyrroline-5-carboxylate reductase. (405 aa)
U7PNF3_SPOS1Aminotran_5 domain-containing protein. (385 aa)
U7PP13_SPOS1Phospho-2-dehydro-3-deoxyheptonate aldolase; Belongs to the class-II DAHP synthase family. (484 aa)
U7PPA3_SPOS1Pyridoxine biosynthesis protein pyroA; Belongs to the PdxS/SNZ family. (330 aa)
U7PPG0_SPOS1Aspartate-semialdehyde dehydrogenase. (372 aa)
U7PPI0_SPOS13-dehydroquinate dehydratase, type I. (791 aa)
U7PPI7_SPOS1Glutaminase A. (472 aa)
U7PPS7_SPOS1Chorismate mutase. (326 aa)
U7PPT1_SPOS1Tryptophan synthase. (721 aa)
U7PPT2_SPOS1Carbamoyl-phosphate synthase arginine-specific small chain. (463 aa)
U7PPX0_SPOS1Homoserine O-acetyltransferase. (576 aa)
U7PQ42_SPOS1Uncharacterized protein. (372 aa)
ADI11,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (172 aa)
Your Current Organism:
Sporothrix schenckii
NCBI taxonomy Id: 1391915
Other names: S. schenckii ATCC 58251, Sporothrix schenckii ATCC 58251
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