147 items (Sporothrix schenckii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	U7PH76_SPOS1	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (568 aa)
	U7PHA5_SPOS1	J domain-containing protein. (378 aa)
	U7PHL3_SPOS1	Cell division control protein 42. (194 aa)
	U7PHT4_SPOS1	IRE protein kinase. (1350 aa)
	U7PHZ1_SPOS1	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (166 aa)
	U7PIP6_SPOS1	Uncharacterized protein. (1039 aa)
	U7PJE4_SPOS1	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (260 aa)
	U7PJP4_SPOS1	U-box domain-containing protein. (1177 aa)
	U7PJX0_SPOS1	Ubiquitin-conjugating enzyme E2 2; Belongs to the ubiquitin-conjugating enzyme family. (151 aa)
	U7PJZ1_SPOS1	Uncharacterized protein. (429 aa)
	U7PKF6_SPOS1	TPR_REGION domain-containing protein. (375 aa)
	U7PKY0_SPOS1	Uncharacterized protein. (1175 aa)
	U7PL08_SPOS1	Uncharacterized protein. (856 aa)
	U7PL10_SPOS1	Uncharacterized protein. (303 aa)
	U7PL14_SPOS1	Putative glutathione-dependent formaldehyde-activating enzyme; Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione; Belongs to the Gfa family. (192 aa)
	U7PL54_SPOS1	Uncharacterized protein. (354 aa)
	U7PL71_SPOS1	Fungal_trans domain-containing protein. (1102 aa)
	U7PLL0_SPOS1	Uncharacterized protein. (114 aa)
	U7PLW1_SPOS1	UBIQUITIN_CONJUGAT_2 domain-containing protein. (350 aa)
	U7PLY6_SPOS1	STE/STE7/MEK1 protein kinase. (590 aa)
	U7PM67_SPOS1	RING-type domain-containing protein. (445 aa)
	U7PMM4_SPOS1	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (656 aa)
	U7PMN5_SPOS1	PfkB domain-containing protein. (360 aa)
	U7PMS1_SPOS1	Uncharacterized protein. (202 aa)
	U7PMY5_SPOS1	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (390 aa)
	U7PN15_SPOS1	Abhydrolase_3 domain-containing protein. (343 aa)
	U7PNB5_SPOS1	BZIP domain-containing protein. (246 aa)
	U7PP87_SPOS1	Uncharacterized protein. (288 aa)
	U7PPH8_SPOS1	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (1183 aa)
	U7PPL4_SPOS1	TPR_REGION domain-containing protein. (1122 aa)
	U7PPN4_SPOS1	Uncharacterized protein. (190 aa)
	U7PPT6_SPOS1	PRKCSH domain-containing protein. (599 aa)
	U7PPX7_SPOS1	NOT2_3_5 domain-containing protein. (511 aa)
	U7PPZ6_SPOS1	PEK/GCN2 protein kinase. (1737 aa)
	U7PQ48_SPOS1	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. (470 aa)
	U7PQE3_SPOS1	Uncharacterized protein. (328 aa)
	U7PQH5_SPOS1	FHA domain-containing protein. (908 aa)
	U7PQM8_SPOS1	S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (305 aa)
	U7PQS5_SPOS1	Uncharacterized protein. (601 aa)
	U7PQY4_SPOS1	STE/STE11 protein kinase. (932 aa)
	U7PR45_SPOS1	Uncharacterized protein; Belongs to the BI1 family. (288 aa)
	U7PRJ2_SPOS1	Uncharacterized protein. (1205 aa)
	U7PRK2_SPOS1	Protein kinase domain-containing protein. (288 aa)
	U7PRU6_SPOS1	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (255 aa)
	U7PRY9_SPOS1	Uncharacterized protein. (277 aa)
	U7PS27_SPOS1	Uncharacterized protein. (1356 aa)
	U7PSI9_SPOS1	RING-CH-type domain-containing protein. (1973 aa)
	U7PSP9_SPOS1	Protein transporter SEC61 subunit alpha. (484 aa)
	U7PSR3_SPOS1	Uncharacterized protein. (344 aa)
	U7PSR8_SPOS1	Hsp7-like protein; Belongs to the heat shock protein 70 family. (673 aa)
	U7PT23_SPOS1	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (530 aa)
	U7PT25_SPOS1	Uncharacterized protein. (772 aa)
	U7PT48_SPOS1	Uncharacterized protein. (733 aa)
	U7PTH2_SPOS1	CUE domain-containing protein. (245 aa)
	U7PTI0_SPOS1	LigB domain-containing protein. (310 aa)
	U7PTT0_SPOS1	Uncharacterized protein. (557 aa)
	U7PU94_SPOS1	PPM-type phosphatase domain-containing protein. (650 aa)
	U7PU99_SPOS1	Non-specific serine/threonine protein kinase. (862 aa)
	U7PUF6_SPOS1	N-acetylmuramic acid 6-phosphate etherase. (345 aa)
	U7PUP1_SPOS1	Guanine nucleotide-binding protein alpha-2 subunit. (354 aa)
	U7PUR5_SPOS1	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1404 aa)
	U7PUW4_SPOS1	Uncharacterized protein. (403 aa)
	U7PV34_SPOS1	NmrA domain-containing protein. (516 aa)
	U7PVA0_SPOS1	Uncharacterized protein. (307 aa)
	U7PVD5_SPOS1	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (327 aa)
	U7PVL5_SPOS1	Uncharacterized protein. (1941 aa)
	U7PVM6_SPOS1	Uncharacterized protein. (242 aa)
	U7PVU8_SPOS1	BZIP domain-containing protein. (447 aa)
	U7PVW6_SPOS1	Nuclear protein localization protein 4. (719 aa)
	U7PW16_SPOS1	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (749 aa)
	U7PW24_SPOS1	Chaperone DnaK; Belongs to the heat shock protein 70 family. (664 aa)
	U7PW29_SPOS1	Uncharacterized protein; Belongs to the cytochrome P450 family. (609 aa)
	U7PW68_SPOS1	Abhydrolase_3 domain-containing protein. (566 aa)
	U7PWB2_SPOS1	N-acetylglucosamine-6-phosphate deacetylase. (489 aa)
	U7PWF2_SPOS1	HECT domain-containing protein. (1168 aa)
	U7PWM1_SPOS1	Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (233 aa)
	U7PWW1_SPOS1	Uncharacterized protein. (349 aa)
	U7PX61_SPOS1	ANK_REP_REGION domain-containing protein. (747 aa)
	U7PX90_SPOS1	TMF_TATA_bd domain-containing protein. (954 aa)
	U7PXN6_SPOS1	Abhydrolase_3 domain-containing protein. (471 aa)
	U7PY17_SPOS1	Uncharacterized protein. (413 aa)
	U7PY74_SPOS1	UBIQUITIN_CONJUGAT_2 domain-containing protein. (308 aa)
	U7PY85_SPOS1	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (234 aa)
	U7PYH0_SPOS1	Uncharacterized protein. (309 aa)
	U7PYJ7_SPOS1	WD_REPEATS_REGION domain-containing protein. (1540 aa)
	U7PYM2_SPOS1	Abhydrolase_3 domain-containing protein. (355 aa)
	U7PYX5_SPOS1	Hsp70-like protein; Belongs to the heat shock protein 70 family. (637 aa)
	U7PZ39_SPOS1	Protein PBN1; Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum. Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase GPI14. (524 aa)
	U7PZ69_SPOS1	Uncharacterized protein. (393 aa)
	U7PZ90_SPOS1	Uncharacterized protein. (660 aa)
	U7PZM2_SPOS1	Uncharacterized protein. (1725 aa)
	U7Q018_SPOS1	Uncharacterized protein. (338 aa)
	U7Q073_SPOS1	Zn(2)-C6 fungal-type domain-containing protein. (767 aa)
	U7Q0A3_SPOS1	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (301 aa)
	U7Q0F4_SPOS1	Uncharacterized protein. (440 aa)
	U7Q0J7_SPOS1	Abhydrolase_3 domain-containing protein. (367 aa)
	U7Q0K5_SPOS1	Guanine nucleotide-binding protein subunit beta. (359 aa)
	U7Q0N3_SPOS1	Guanine nucleotide-binding protein subunit gamma. (93 aa)
	U7Q0W8_SPOS1	Serine/threonine protein kinase. (624 aa)
	U7Q136_SPOS1	Hsp98-like protein; Belongs to the ClpA/ClpB family. (930 aa)
	U7Q139_SPOS1	Uncharacterized protein. (431 aa)
	U7Q155_SPOS1	Cell division control protein 48. (830 aa)
	U7Q164_SPOS1	Opy2 domain-containing protein. (477 aa)
	U7Q1C0_SPOS1	Uncharacterized protein. (182 aa)
	U7Q1G5_SPOS1	Uncharacterized protein. (360 aa)
	U7Q1L8_SPOS1	BAG domain-containing protein. (337 aa)
	U7Q1T0_SPOS1	Long chronological lifespan protein 2; Probable component of the endoplasmic reticulum-associated degradation (ERAD) pathway. (122 aa)
	U7Q1U6_SPOS1	Uncharacterized protein. (389 aa)
	U7Q1W1_SPOS1	Uncharacterized protein. (364 aa)
	U7Q1Y9_SPOS1	Uncharacterized protein. (502 aa)
	U7Q228_SPOS1	STE/STE20/PAKA protein kinase. (1023 aa)
	U7Q2B2_SPOS1	UV excision repair protein Rad23. (447 aa)
	U7Q2H1_SPOS1	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (459 aa)
	U7Q2H4_SPOS1	P-type phospholipid transporter. (1934 aa)
	U7Q2I2_SPOS1	Uncharacterized protein. (831 aa)
	U7Q2N6_SPOS1	RPOL4c domain-containing protein. (142 aa)
	U7Q2P9_SPOS1	Uncharacterized protein. (762 aa)
	U7Q2Y7_SPOS1	Abhydrolase_3 domain-containing protein. (340 aa)
	U7Q308_SPOS1	Uncharacterized protein. (870 aa)
	U7Q343_SPOS1	RING-type domain-containing protein. (925 aa)
	U7Q350_SPOS1	Uncharacterized protein. (342 aa)
	U7Q371_SPOS1	Uncharacterized protein. (344 aa)
	U7Q375_SPOS1	Calcineurin subunit B. (174 aa)
	U7Q387_SPOS1	Uncharacterized protein. (412 aa)
	U7Q3M2_SPOS1	Uncharacterized protein. (866 aa)
	U7Q3Y0_SPOS1	Uncharacterized protein. (749 aa)
	U7Q496_SPOS1	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (1043 aa)
	U7Q4B1_SPOS1	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1328 aa)
	U7Q4G4_SPOS1	Hsp90-like protein. (707 aa)
	U7Q4K1_SPOS1	Uncharacterized protein. (489 aa)
	U7Q4W1_SPOS1	Methyltranfer_dom domain-containing protein. (710 aa)
	U7Q4W6_SPOS1	Uncharacterized protein. (463 aa)
	U7Q511_SPOS1	Uncharacterized protein. (472 aa)
	U7Q533_SPOS1	Adenylyl cyclase-associated protein; Belongs to the CAP family. (568 aa)
	U7Q591_SPOS1	TUG-UBL1 domain-containing protein. (529 aa)
	U7Q5F8_SPOS1	CsbD domain-containing protein. (187 aa)
	U7Q5L1_SPOS1	Ubiquitin carboxyl-terminal hydrolase. (336 aa)
	U7Q5N2_SPOS1	Uncharacterized protein. (991 aa)
	U7Q7R5_SPOS1	Uncharacterized protein. (360 aa)
	U7Q7Q6_SPOS1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (355 aa)
	U7Q7C7_SPOS1	Uncharacterized protein. (1507 aa)
	U7Q7A2_SPOS1	OTU domain-containing protein. (329 aa)
	U7Q6W4_SPOS1	Uncharacterized protein. (353 aa)
	U7Q6I0_SPOS1	Zn(2)-C6 fungal-type domain-containing protein. (826 aa)
	U7Q625_SPOS1	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (626 aa)
	U7Q5U3_SPOS1	N-acetyltransferase domain-containing protein. (190 aa)
	U7Q5R2_SPOS1	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (650 aa)

Your Current Organism:

Sporothrix schenckii

NCBI taxonomy Id: 1391915
Other names: S. schenckii ATCC 58251, Sporothrix schenckii ATCC 58251

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
U7PH76_SPOS1	U7PKF6_SPOS1	U7PH76	U7PKF6	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	TPR_REGION domain-containing protein.	0.469
U7PH76_SPOS1	U7PPL4_SPOS1	U7PH76	U7PPL4	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	TPR_REGION domain-containing protein.	0.469
U7PH76_SPOS1	U7PQE3_SPOS1	U7PH76	U7PQE3	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Uncharacterized protein.	0.444
U7PH76_SPOS1	U7PRJ2_SPOS1	U7PH76	U7PRJ2	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Uncharacterized protein.	0.484
U7PH76_SPOS1	U7PS27_SPOS1	U7PH76	U7PS27	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Uncharacterized protein.	0.594
U7PH76_SPOS1	U7PU94_SPOS1	U7PH76	U7PU94	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	PPM-type phosphatase domain-containing protein.	0.464
U7PH76_SPOS1	U7PVA0_SPOS1	U7PH76	U7PVA0	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Uncharacterized protein.	0.444
U7PH76_SPOS1	U7PVD5_SPOS1	U7PH76	U7PVD5	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.444
U7PH76_SPOS1	U7PWW1_SPOS1	U7PH76	U7PWW1	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Uncharacterized protein.	0.444
U7PH76_SPOS1	U7PYH0_SPOS1	U7PH76	U7PYH0	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Uncharacterized protein.	0.444
U7PH76_SPOS1	U7PZ90_SPOS1	U7PH76	U7PZ90	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Uncharacterized protein.	0.479
U7PH76_SPOS1	U7Q018_SPOS1	U7PH76	U7Q018	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Uncharacterized protein.	0.444
U7PH76_SPOS1	U7Q1G5_SPOS1	U7PH76	U7Q1G5	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Uncharacterized protein.	0.444
U7PH76_SPOS1	U7Q1U6_SPOS1	U7PH76	U7Q1U6	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Uncharacterized protein.	0.488
U7PH76_SPOS1	U7Q1W1_SPOS1	U7PH76	U7Q1W1	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Uncharacterized protein.	0.444
U7PH76_SPOS1	U7Q350_SPOS1	U7PH76	U7Q350	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Uncharacterized protein.	0.444
U7PH76_SPOS1	U7Q6W4_SPOS1	U7PH76	U7Q6W4	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Uncharacterized protein.	0.444
U7PH76_SPOS1	U7Q7R5_SPOS1	U7PH76	U7Q7R5	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Uncharacterized protein.	0.444
U7PHA5_SPOS1	U7PIP6_SPOS1	U7PHA5	U7PIP6	J domain-containing protein.	Uncharacterized protein.	0.719
U7PHA5_SPOS1	U7PKF6_SPOS1	U7PHA5	U7PKF6	J domain-containing protein.	TPR_REGION domain-containing protein.	0.517