STRINGSTRING
U7PHD2_SPOS1 U7PHD2_SPOS1 U7PHE9_SPOS1 U7PHE9_SPOS1 U7PHK2_SPOS1 U7PHK2_SPOS1 U7PJ10_SPOS1 U7PJ10_SPOS1 U7PK01_SPOS1 U7PK01_SPOS1 U7PKQ3_SPOS1 U7PKQ3_SPOS1 U7PKX9_SPOS1 U7PKX9_SPOS1 uba4 uba4 U7PLI2_SPOS1 U7PLI2_SPOS1 U7PM84_SPOS1 U7PM84_SPOS1 U7PMC5_SPOS1 U7PMC5_SPOS1 U7PMQ0_SPOS1 U7PMQ0_SPOS1 U7PNP6_SPOS1 U7PNP6_SPOS1 U7PNW1_SPOS1 U7PNW1_SPOS1 U7PNY2_SPOS1 U7PNY2_SPOS1 U7PP21_SPOS1 U7PP21_SPOS1 U7PP73_SPOS1 U7PP73_SPOS1 U7PPC4_SPOS1 U7PPC4_SPOS1 U7PPH9_SPOS1 U7PPH9_SPOS1 U7PPI3_SPOS1 U7PPI3_SPOS1 U7PPR9_SPOS1 U7PPR9_SPOS1 U7PQ43_SPOS1 U7PQ43_SPOS1 U7PQA3_SPOS1 U7PQA3_SPOS1 U7PQF1_SPOS1 U7PQF1_SPOS1 U7PQG7_SPOS1 U7PQG7_SPOS1 U7PQJ1_SPOS1 U7PQJ1_SPOS1 U7PQM3_SPOS1 U7PQM3_SPOS1 U7PQT8_SPOS1 U7PQT8_SPOS1 U7PRM5_SPOS1 U7PRM5_SPOS1 U7PS64_SPOS1 U7PS64_SPOS1 U7PS81_SPOS1 U7PS81_SPOS1 U7PSR3_SPOS1 U7PSR3_SPOS1 MET3 MET3 U7PTK7_SPOS1 U7PTK7_SPOS1 U7PUB9_SPOS1 U7PUB9_SPOS1 U7PV31_SPOS1 U7PV31_SPOS1 U7PVM8_SPOS1 U7PVM8_SPOS1 NCS6 NCS6 U7PW76_SPOS1 U7PW76_SPOS1 U7PWN1_SPOS1 U7PWN1_SPOS1 U7PX37_SPOS1 U7PX37_SPOS1 U7PXC8_SPOS1 U7PXC8_SPOS1 U7PXK4_SPOS1 U7PXK4_SPOS1 U7PXU5_SPOS1 U7PXU5_SPOS1 U7PY40_SPOS1 U7PY40_SPOS1 U7PYK4_SPOS1 U7PYK4_SPOS1 U7PYP9_SPOS1 U7PYP9_SPOS1 U7PYR7_SPOS1 U7PYR7_SPOS1 U7PYW4_SPOS1 U7PYW4_SPOS1 U7PZD3_SPOS1 U7PZD3_SPOS1 U7Q0T2_SPOS1 U7Q0T2_SPOS1 U7Q0V3_SPOS1 U7Q0V3_SPOS1 U7Q1C8_SPOS1 U7Q1C8_SPOS1 U7Q1P4_SPOS1 U7Q1P4_SPOS1 U7Q1S7_SPOS1 U7Q1S7_SPOS1 U7Q1W6_SPOS1 U7Q1W6_SPOS1 U7Q274_SPOS1 U7Q274_SPOS1 U7Q289_SPOS1 U7Q289_SPOS1 U7Q2D6_SPOS1 U7Q2D6_SPOS1 U7Q2N5_SPOS1 U7Q2N5_SPOS1 U7Q3U9_SPOS1 U7Q3U9_SPOS1 U7Q467_SPOS1 U7Q467_SPOS1 U7Q4K5_SPOS1 U7Q4K5_SPOS1 U7Q4U5_SPOS1 U7Q4U5_SPOS1 U7Q4V5_SPOS1 U7Q4V5_SPOS1 U7Q4W4_SPOS1 U7Q4W4_SPOS1 U7Q596_SPOS1 U7Q596_SPOS1 U7Q5K3_SPOS1 U7Q5K3_SPOS1 U7Q5K6_SPOS1 U7Q5K6_SPOS1 U7Q5T0_SPOS1 U7Q5T0_SPOS1 U7Q6L6_SPOS1 U7Q6L6_SPOS1 U7Q846_SPOS1 U7Q846_SPOS1 U7Q886_SPOS1 U7Q886_SPOS1 U7Q8Z6_SPOS1 U7Q8Z6_SPOS1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
U7PHD2_SPOS1UmuC domain-containing protein. (513 aa)
U7PHE9_SPOS1Uncharacterized protein. (755 aa)
U7PHK2_SPOS1Nicotinate (Nicotinamide) nucleotide adenylyltransferase. (234 aa)
U7PJ10_SPOS1Uncharacterized protein. (383 aa)
U7PK01_SPOS1Uncharacterized protein. (756 aa)
U7PKQ3_SPOS1RNA-dependent RNA polymerase. (1301 aa)
U7PKX9_SPOS1DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1321 aa)
uba4Adenylyltransferase and sulfurtransferase uba4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and MOCS2A. Its N-terminus first activates urm1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...] (489 aa)
U7PLI2_SPOS1Uncharacterized protein. (237 aa)
U7PM84_SPOS1Uncharacterized protein. (237 aa)
U7PMC5_SPOS1BPL/LPL catalytic domain-containing protein. (465 aa)
U7PMQ0_SPOS1Uncharacterized protein. (486 aa)
U7PNP6_SPOS1DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1170 aa)
U7PNW1_SPOS1Uncharacterized protein. (396 aa)
U7PNY2_SPOS1Uncharacterized protein. (1434 aa)
U7PP21_SPOS1ATP_transf domain-containing protein. (365 aa)
U7PP73_SPOS1Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (735 aa)
U7PPC4_SPOS1Galactose-1-phosphate uridylyltransferase; Belongs to the galactose-1-phosphate uridylyltransferase type 1 family. (392 aa)
U7PPH9_SPOS1RPOLD domain-containing protein. (356 aa)
U7PPI3_SPOS1Uncharacterized protein. (572 aa)
U7PPR9_SPOS1Uncharacterized protein. (445 aa)
U7PQ43_SPOS1RNA_pol_L_2 domain-containing protein. (156 aa)
U7PQA3_SPOS1DNA polymerase. (1545 aa)
U7PQF1_SPOS1CTP_transf_like domain-containing protein. (460 aa)
U7PQG7_SPOS1Uncharacterized protein. (1727 aa)
U7PQJ1_SPOS1RNA-dependent RNA polymerase. (1442 aa)
U7PQM3_SPOS1Uncharacterized protein. (171 aa)
U7PQT8_SPOS1DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1272 aa)
U7PRM5_SPOS1DNA polymerase. (1652 aa)
U7PS64_SPOS1Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1162 aa)
U7PS81_SPOS1UTP--glucose-1-phosphate uridylyltransferase. (514 aa)
U7PSR3_SPOS1Uncharacterized protein. (344 aa)
MET3Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. In the N-terminal section; belongs to the sulfate adenylyltransferase family. (573 aa)
U7PTK7_SPOS1PAP-associated domain-containing protein. (1234 aa)
U7PUB9_SPOS1Mannose-1-phosphate guanyltransferase. (364 aa)
U7PV31_SPOS1Uncharacterized protein. (916 aa)
U7PVM8_SPOS1DNA-directed RNA polymerase I, II, and III subunit RPABC5. (77 aa)
NCS6Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. (445 aa)
U7PW76_SPOS1DNA polymerase. (1115 aa)
U7PWN1_SPOS1DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2402 aa)
U7PX37_SPOS1Uncharacterized protein. (1590 aa)
U7PXC8_SPOS1DNA-directed RNA polymerase. (195 aa)
U7PXK4_SPOS1DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (632 aa)
U7PXU5_SPOS1RPA43_OB domain-containing protein. (387 aa)
U7PY40_SPOS1Phosphatidate cytidylyltransferase; Belongs to the CDS family. (449 aa)
U7PYK4_SPOS1mRNA-capping enzyme subunit alpha; Second step of mRNA capping. Transfer of the GMP moiety of GTP to the 5'-end of RNA via an enzyme-GMP covalent reaction intermediate; Belongs to the eukaryotic GTase family. (404 aa)
U7PYP9_SPOS1UmuC domain-containing protein. (671 aa)
U7PYR7_SPOS1Fido domain-containing protein. (363 aa)
U7PYW4_SPOS1Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (616 aa)
U7PZD3_SPOS1YrdC-like domain-containing protein. (242 aa)
U7Q0T2_SPOS1Uncharacterized protein; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (612 aa)
U7Q0V3_SPOS1Uncharacterized protein. (478 aa)
U7Q1C8_SPOS1Uncharacterized protein. (476 aa)
U7Q1P4_SPOS1Uncharacterized protein. (816 aa)
U7Q1S7_SPOS1DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1483 aa)
U7Q1W6_SPOS1DNA-directed RNA polymerase III subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. (291 aa)
U7Q274_SPOS1tRNA(His) guanylyltransferase; Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. (297 aa)
U7Q289_SPOS1POLAc domain-containing protein. (1193 aa)
U7Q2D6_SPOS1PAPS_reduct domain-containing protein. (350 aa)
U7Q2N5_SPOS1RPOLD domain-containing protein. (376 aa)
U7Q3U9_SPOS1HORMA domain-containing protein. (352 aa)
U7Q467_SPOS1W2 domain-containing protein. (861 aa)
U7Q4K5_SPOS1DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (468 aa)
U7Q4U5_SPOS1RNA_pol_L_2 domain-containing protein. (135 aa)
U7Q4V5_SPOS1Uncharacterized protein. (548 aa)
U7Q4W4_SPOS1DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1266 aa)
U7Q596_SPOS1CTP_transf_like domain-containing protein. (494 aa)
U7Q5K3_SPOS1DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1760 aa)
U7Q5K6_SPOS1NTP_transferase domain-containing protein. (445 aa)
U7Q5T0_SPOS1Sua5/YciO/YrdC/YwlC family protein. (463 aa)
U7Q6L6_SPOS1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (589 aa)
U7Q846_SPOS1Uncharacterized protein. (509 aa)
U7Q886_SPOS1CTP_transf_like domain-containing protein. (440 aa)
U7Q8Z6_SPOS1DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family. (1625 aa)
Your Current Organism:
Sporothrix schenckii
NCBI taxonomy Id: 1391915
Other names: S. schenckii ATCC 58251, Sporothrix schenckii ATCC 58251
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.