23 items (Sporothrix schenckii) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Your Input:
	U7Q472_SPOS1	HRDC domain-containing protein. (875 aa)
	U7Q5T3_SPOS1	Uncharacterized protein. (601 aa)
	U7Q7W4_SPOS1	zf-C2HE domain-containing protein. (353 aa)
	U7Q8V5_SPOS1	Exonuclease domain-containing protein. (211 aa)
	U7PPB0_SPOS1	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (814 aa)
	USB1	U6 snRNA phosphodiesterase; Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA; Belongs to the 2H phosphoesterase superfamily. USB1 family. (360 aa)
	U7PUH0_SPOS1	Uncharacterized protein. (422 aa)
	PAN2	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...] (1297 aa)
	U7PUY3_SPOS1	Uncharacterized protein. (844 aa)
	U7PW71_SPOS1	RNB domain-containing protein. (1385 aa)
	U7PW76_SPOS1	DNA polymerase. (1115 aa)
	U7PWN1_SPOS1	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2402 aa)
	U7PZT2_SPOS1	Uncharacterized protein. (668 aa)
	U7Q0R4_SPOS1	Uncharacterized protein. (668 aa)
	U7Q2C1_SPOS1	Uncharacterized protein. (581 aa)
	U7Q2E4_SPOS1	Uncharacterized protein. (458 aa)
	U7PKL3_SPOS1	XPGI domain-containing protein. (299 aa)
	U7PKL1_SPOS1	DRMBL domain-containing protein. (949 aa)
	U7PKF2_SPOS1	5'-3' exoribonuclease 2. (2077 aa)
	U7PHX2_SPOS1	Uncharacterized protein; Belongs to the RNR ribonuclease family. (1032 aa)
	U7Q2G7_SPOS1	3'-5' exonuclease domain-containing protein. (579 aa)
	U7Q2V1_SPOS1	RNB domain-containing protein. (1186 aa)
	U7Q3Y8_SPOS1	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins. (1492 aa)

Your Current Organism:

Sporothrix schenckii

NCBI taxonomy Id: 1391915
Other names: S. schenckii ATCC 58251, Sporothrix schenckii ATCC 58251

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PAN2	U7PHX2_SPOS1	U7PUU3	U7PHX2	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...]	Uncharacterized protein; Belongs to the RNR ribonuclease family.	0.596
PAN2	U7PW71_SPOS1	U7PUU3	U7PW71	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...]	RNB domain-containing protein.	0.596
PAN2	U7Q0R4_SPOS1	U7PUU3	U7Q0R4	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...]	Uncharacterized protein.	0.793
PAN2	U7Q2C1_SPOS1	U7PUU3	U7Q2C1	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...]	Uncharacterized protein.	0.533
PAN2	U7Q2E4_SPOS1	U7PUU3	U7Q2E4	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...]	Uncharacterized protein.	0.471
PAN2	U7Q2V1_SPOS1	U7PUU3	U7Q2V1	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...]	RNB domain-containing protein.	0.595
PAN2	U7Q3Y8_SPOS1	U7PUU3	U7Q3Y8	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...]	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.	0.531
PAN2	U7Q8V5_SPOS1	U7PUU3	U7Q8V5	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...]	Exonuclease domain-containing protein.	0.674
U7PHX2_SPOS1	PAN2	U7PHX2	U7PUU3	Uncharacterized protein; Belongs to the RNR ribonuclease family.	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...]	0.596
U7PHX2_SPOS1	U7Q2E4_SPOS1	U7PHX2	U7Q2E4	Uncharacterized protein; Belongs to the RNR ribonuclease family.	Uncharacterized protein.	0.659
U7PHX2_SPOS1	U7Q3Y8_SPOS1	U7PHX2	U7Q3Y8	Uncharacterized protein; Belongs to the RNR ribonuclease family.	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.	0.840
U7PHX2_SPOS1	U7Q472_SPOS1	U7PHX2	U7Q472	Uncharacterized protein; Belongs to the RNR ribonuclease family.	HRDC domain-containing protein.	0.807
U7PKF2_SPOS1	U7Q3Y8_SPOS1	U7PKF2	U7Q3Y8	5'-3' exoribonuclease 2.	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.	0.961
U7PKF2_SPOS1	U7Q472_SPOS1	U7PKF2	U7Q472	5'-3' exoribonuclease 2.	HRDC domain-containing protein.	0.529
U7PKL1_SPOS1	U7PKL3_SPOS1	U7PKL1	U7PKL3	DRMBL domain-containing protein.	XPGI domain-containing protein.	0.656
U7PKL1_SPOS1	U7PPB0_SPOS1	U7PKL1	U7PPB0	DRMBL domain-containing protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.807
U7PKL1_SPOS1	U7Q472_SPOS1	U7PKL1	U7Q472	DRMBL domain-containing protein.	HRDC domain-containing protein.	0.763
U7PKL3_SPOS1	U7PKL1_SPOS1	U7PKL3	U7PKL1	XPGI domain-containing protein.	DRMBL domain-containing protein.	0.656
U7PKL3_SPOS1	U7PPB0_SPOS1	U7PKL3	U7PPB0	XPGI domain-containing protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.987
U7PKL3_SPOS1	U7PUY3_SPOS1	U7PKL3	U7PUY3	XPGI domain-containing protein.	Uncharacterized protein.	0.838