58 items (Sporothrix schenckii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	U7PUI8_SPOS1	18S rRNA biogenesis protein RCL1. (415 aa)
	U7PHH6_SPOS1	WD_REPEATS_REGION domain-containing protein. (573 aa)
	U7PHJ2_SPOS1	Uncharacterized protein. (276 aa)
	U7PJ87_SPOS1	Bms1-type G domain-containing protein. (791 aa)
	U7PJD0_SPOS1	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (211 aa)
	U7PJL0_SPOS1	40S ribosomal protein S21; Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Has a physiological role leading to 18S rRNA stability. (87 aa)
	U7PKA3_SPOS1	20S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family. (477 aa)
	U7PKD7_SPOS1	40S ribosomal protein S13; Belongs to the universal ribosomal protein uS15 family. (151 aa)
	U7PKI9_SPOS1	CBF domain-containing protein. (607 aa)
	U7PL25_SPOS1	WD_REPEATS_REGION domain-containing protein. (915 aa)
	TSR3	Ribosome biogenesis protein TSR3; Ribosome biogenesis protein required for processing 35S pre- rRNA at site D; Belongs to the TSR3 family. (406 aa)
	U7PLI3_SPOS1	Uncharacterized protein. (1310 aa)
	U7PM63_SPOS1	Uncharacterized protein. (272 aa)
	U7PN34_SPOS1	40S ribosomal protein S8; Belongs to the eukaryotic ribosomal protein eS8 family. (202 aa)
	U7PNL2_SPOS1	WD_REPEATS_REGION domain-containing protein. (1022 aa)
	U7PNV7_SPOS1	40S ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family. (150 aa)
	U7PPI6_SPOS1	Uncharacterized protein. (827 aa)
	U7PPM4_SPOS1	Bms1-type G domain-containing protein. (1175 aa)
	U7PPR1_SPOS1	Utp12 domain-containing protein. (477 aa)
	U7PPZ2_SPOS1	Uncharacterized protein. (841 aa)
	U7PQK3_SPOS1	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (127 aa)
	U7PQT2_SPOS1	Sas10 domain-containing protein. (683 aa)
	U7PQW2_SPOS1	Uncharacterized protein. (614 aa)
	U7PRT4_SPOS1	Sm domain-containing protein. (216 aa)
	U7PRY7_SPOS1	Uncharacterized protein. (503 aa)
	U7PRZ9_SPOS1	Atypical/RIO/RIO2 protein kinase. (420 aa)
	U7PTJ1_SPOS1	Uncharacterized protein. (1091 aa)
	U7PUF5_SPOS1	Nop domain-containing protein. (594 aa)
	U7PUL5_SPOS1	Uncharacterized protein. (127 aa)
	U7PV23_SPOS1	Uncharacterized protein. (981 aa)
	U7PVM2_SPOS1	Uncharacterized protein. (331 aa)
	U7PVT8_SPOS1	Uncharacterized protein. (1033 aa)
	U7PVU9_SPOS1	Uncharacterized protein. (945 aa)
	U7PWF1_SPOS1	Uncharacterized protein. (440 aa)
	U7PWK8_SPOS1	Uncharacterized protein. (577 aa)
	U7PWX5_SPOS1	rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (376 aa)
	U7PWY8_SPOS1	Uncharacterized protein. (163 aa)
	U7PY09_SPOS1	40S ribosomal protein S28. (68 aa)
	U7PY77_SPOS1	WD_REPEATS_REGION domain-containing protein. (576 aa)
	U7PY88_SPOS1	WD_REPEATS_REGION domain-containing protein. (1008 aa)
	U7PZ57_SPOS1	Kri1_C domain-containing protein. (766 aa)
	U7Q0R5_SPOS1	Fcf2 domain-containing protein. (205 aa)
	U7Q206_SPOS1	Uncharacterized protein. (1841 aa)
	U7Q2J7_SPOS1	40S ribosomal protein S16; Belongs to the universal ribosomal protein uS9 family. (141 aa)
	U7Q2X4_SPOS1	Uncharacterized protein. (367 aa)
	U7Q334_SPOS1	KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. (329 aa)
	U7Q367_SPOS1	Uncharacterized protein. (408 aa)
	U7Q3H4_SPOS1	PDCD2_C domain-containing protein. (464 aa)
	U7Q421_SPOS1	Uncharacterized protein. (220 aa)
	U7Q440_SPOS1	WD_REPEATS_REGION domain-containing protein. (666 aa)
	NAT10	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1164 aa)
	U7Q4H6_SPOS1	WD_REPEATS_REGION domain-containing protein. (673 aa)
	U7Q4N6_SPOS1	WD_REPEATS_REGION domain-containing protein. (989 aa)
	U7Q563_SPOS1	Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation. (211 aa)
	U7Q5V2_SPOS1	WD_REPEATS_REGION domain-containing protein. (1021 aa)
	U7Q7N1_SPOS1	Uncharacterized protein. (404 aa)
	U7Q827_SPOS1	WD_REPEATS_REGION domain-containing protein. (477 aa)
	U7Q8L1_SPOS1	Uncharacterized protein. (821 aa)

Your Current Organism:

Sporothrix schenckii

NCBI taxonomy Id: 1391915
Other names: S. schenckii ATCC 58251, Sporothrix schenckii ATCC 58251

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NAT10	TSR3	U7Q471	U7PL60	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Ribosome biogenesis protein TSR3; Ribosome biogenesis protein required for processing 35S pre- rRNA at site D; Belongs to the TSR3 family.	0.459
NAT10	U7PHH6_SPOS1	U7Q471	U7PHH6	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	WD_REPEATS_REGION domain-containing protein.	0.998
NAT10	U7PHJ2_SPOS1	U7Q471	U7PHJ2	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Uncharacterized protein.	0.967
NAT10	U7PJ87_SPOS1	U7Q471	U7PJ87	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Bms1-type G domain-containing protein.	0.937
NAT10	U7PJD0_SPOS1	U7Q471	U7PJD0	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family.	0.769
NAT10	U7PKA3_SPOS1	U7Q471	U7PKA3	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	20S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family.	0.771
NAT10	U7PKD7_SPOS1	U7Q471	U7PKD7	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	40S ribosomal protein S13; Belongs to the universal ribosomal protein uS15 family.	0.934
NAT10	U7PKI9_SPOS1	U7Q471	U7PKI9	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	CBF domain-containing protein.	0.995
NAT10	U7PL25_SPOS1	U7Q471	U7PL25	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	WD_REPEATS_REGION domain-containing protein.	0.998
NAT10	U7PLI3_SPOS1	U7Q471	U7PLI3	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Uncharacterized protein.	0.964
NAT10	U7PM63_SPOS1	U7Q471	U7PM63	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Uncharacterized protein.	0.874
NAT10	U7PN34_SPOS1	U7Q471	U7PN34	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	40S ribosomal protein S8; Belongs to the eukaryotic ribosomal protein eS8 family.	0.933
NAT10	U7PNL2_SPOS1	U7Q471	U7PNL2	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	WD_REPEATS_REGION domain-containing protein.	0.992
NAT10	U7PNV7_SPOS1	U7Q471	U7PNV7	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	40S ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family.	0.917
NAT10	U7PPI6_SPOS1	U7Q471	U7PPI6	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Uncharacterized protein.	0.984
NAT10	U7PPM4_SPOS1	U7Q471	U7PPM4	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Bms1-type G domain-containing protein.	0.999
NAT10	U7PPR1_SPOS1	U7Q471	U7PPR1	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Utp12 domain-containing protein.	0.993
NAT10	U7PPZ2_SPOS1	U7Q471	U7PPZ2	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Uncharacterized protein.	0.867
NAT10	U7PQK3_SPOS1	U7Q471	U7PQK3	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.	0.969
NAT10	U7PQT2_SPOS1	U7Q471	U7PQT2	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Sas10 domain-containing protein.	0.983