33 items (Sporothrix schenckii) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	U7PHN5_SPOS1	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (471 aa)
	U7PJ69_SPOS1	AAA domain-containing protein. (768 aa)
	U7PJX0_SPOS1	Ubiquitin-conjugating enzyme E2 2; Belongs to the ubiquitin-conjugating enzyme family. (151 aa)
	U7PK95_SPOS1	Helicase ATP-binding domain-containing protein. (957 aa)
	U7PKY9_SPOS1	Uncharacterized protein. (477 aa)
	MCM7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (835 aa)
	U7PMG1_SPOS1	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (495 aa)
	U7PNM4_SPOS1	Uncharacterized protein. (2263 aa)
	U7PNX6_SPOS1	AAA_23 domain-containing protein. (1331 aa)
	U7PPQ6_SPOS1	Uncharacterized protein. (657 aa)
	U7PQV4_SPOS1	Uncharacterized protein. (1870 aa)
	U7PSF8_SPOS1	DNA helicase; Belongs to the MCM family. (886 aa)
	U7PSZ7_SPOS1	Uncharacterized protein. (1800 aa)
	U7PTJ8_SPOS1	Uncharacterized protein. (1266 aa)
	U7PU04_SPOS1	HD domain-containing protein. (279 aa)
	U7PX11_SPOS1	Uncharacterized protein. (1912 aa)
	U7PXL6_SPOS1	Uncharacterized protein. (1304 aa)
	U7PYU5_SPOS1	DNA helicase; Belongs to the MCM family. (981 aa)
	U7PYX8_SPOS1	SAP domain-containing protein. (736 aa)
	U7PYY3_SPOS1	Uncharacterized protein. (1106 aa)
	U7Q096_SPOS1	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (458 aa)
	U7Q0J8_SPOS1	FHA domain-containing protein. (992 aa)
	U7Q0Q0_SPOS1	VWFA domain-containing protein. (744 aa)
	U7Q2I4_SPOS1	DNA helicase; Belongs to the MCM family. (1070 aa)
	U7Q3D6_SPOS1	Uncharacterized protein. (618 aa)
	U7Q3Z2_SPOS1	DNA helicase; Belongs to the MCM family. (746 aa)
	U7Q4H2_SPOS1	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (628 aa)
	U7Q4P6_SPOS1	Uncharacterized protein. (1718 aa)
	U7Q5N1_SPOS1	Uncharacterized protein. (1227 aa)
	U7Q5V7_SPOS1	Uncharacterized protein. (858 aa)
	U7Q723_SPOS1	DNA helicase; Belongs to the MCM family. (934 aa)
	U7Q7L3_SPOS1	Uncharacterized protein. (1143 aa)
	U7Q9L5_SPOS1	Uncharacterized protein. (169 aa)

Your Current Organism:

Sporothrix schenckii

NCBI taxonomy Id: 1391915
Other names: S. schenckii ATCC 58251, Sporothrix schenckii ATCC 58251

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MCM7	U7PMG1_SPOS1	U7PLF0	U7PMG1	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.445
MCM7	U7PQV4_SPOS1	U7PLF0	U7PQV4	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Uncharacterized protein.	0.445
MCM7	U7PSF8_SPOS1	U7PLF0	U7PSF8	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	U7PYU5_SPOS1	U7PLF0	U7PYU5	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	U7Q2I4_SPOS1	U7PLF0	U7Q2I4	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	U7Q3Z2_SPOS1	U7PLF0	U7Q3Z2	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	U7Q4H2_SPOS1	U7PLF0	U7Q4H2	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.864
MCM7	U7Q723_SPOS1	U7PLF0	U7Q723	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
U7PHN5_SPOS1	U7PNM4_SPOS1	U7PHN5	U7PNM4	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.	Uncharacterized protein.	0.605
U7PHN5_SPOS1	U7PX11_SPOS1	U7PHN5	U7PX11	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.	Uncharacterized protein.	0.995
U7PHN5_SPOS1	U7PYU5_SPOS1	U7PHN5	U7PYU5	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.	DNA helicase; Belongs to the MCM family.	0.415
U7PHN5_SPOS1	U7Q096_SPOS1	U7PHN5	U7Q096	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.	0.999
U7PHN5_SPOS1	U7Q2I4_SPOS1	U7PHN5	U7Q2I4	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.	DNA helicase; Belongs to the MCM family.	0.440
U7PHN5_SPOS1	U7Q3Z2_SPOS1	U7PHN5	U7Q3Z2	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.	DNA helicase; Belongs to the MCM family.	0.455
U7PHN5_SPOS1	U7Q4H2_SPOS1	U7PHN5	U7Q4H2	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.428
U7PHN5_SPOS1	U7Q723_SPOS1	U7PHN5	U7Q723	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.	DNA helicase; Belongs to the MCM family.	0.458
U7PHN5_SPOS1	U7Q7L3_SPOS1	U7PHN5	U7Q7L3	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.	Uncharacterized protein.	0.477
U7PJX0_SPOS1	U7PK95_SPOS1	U7PJX0	U7PK95	Ubiquitin-conjugating enzyme E2 2; Belongs to the ubiquitin-conjugating enzyme family.	Helicase ATP-binding domain-containing protein.	0.532
U7PJX0_SPOS1	U7PMG1_SPOS1	U7PJX0	U7PMG1	Ubiquitin-conjugating enzyme E2 2; Belongs to the ubiquitin-conjugating enzyme family.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.538
U7PJX0_SPOS1	U7PNX6_SPOS1	U7PJX0	U7PNX6	Ubiquitin-conjugating enzyme E2 2; Belongs to the ubiquitin-conjugating enzyme family.	AAA_23 domain-containing protein.	0.554