20 items (Sporothrix schenckii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	U7PT25_SPOS1	Uncharacterized protein. (772 aa)
	U7Q7H5_SPOS1	TFIID_20kDa domain-containing protein. (830 aa)
	U7Q6Z0_SPOS1	Acyl_transf_3 domain-containing protein. (434 aa)
	U7Q4Q9_SPOS1	Transcription elongation factor S-II. (311 aa)
	U7Q3S9_SPOS1	Uncharacterized protein. (412 aa)
	U7Q0H8_SPOS1	TAF domain-containing protein. (503 aa)
	U7Q091_SPOS1	TAFII28 domain-containing protein. (370 aa)
	U7Q073_SPOS1	Zn(2)-C6 fungal-type domain-containing protein. (767 aa)
	U7PYB0_SPOS1	DUF3591 domain-containing protein. (1140 aa)
	U7PWX9_SPOS1	Uncharacterized protein. (262 aa)
	U7PVZ2_SPOS1	CBFD_NFYB_HMF domain-containing protein. (389 aa)
	U7PRE2_SPOS1	CBFD_NFYB_HMF domain-containing protein. (140 aa)
	U7PPJ1_SPOS1	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (111 aa)
	U7PPJ0_SPOS1	Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...] (239 aa)
	U7PML0_SPOS1	Uncharacterized protein. (300 aa)
	U7PMC1_SPOS1	Uncharacterized protein. (416 aa)
	U7PL71_SPOS1	Fungal_trans domain-containing protein. (1102 aa)
	U7PKU7_SPOS1	TAFII55_N domain-containing protein. (595 aa)
	U7PJY3_SPOS1	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (755 aa)
	U7PHY5_SPOS1	TFIIB-type domain-containing protein. (868 aa)

Your Current Organism:

Sporothrix schenckii

NCBI taxonomy Id: 1391915
Other names: S. schenckii ATCC 58251, Sporothrix schenckii ATCC 58251

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
U7PHY5_SPOS1	U7PJY3_SPOS1	U7PHY5	U7PJY3	TFIIB-type domain-containing protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.801
U7PHY5_SPOS1	U7PKU7_SPOS1	U7PHY5	U7PKU7	TFIIB-type domain-containing protein.	TAFII55_N domain-containing protein.	0.924
U7PHY5_SPOS1	U7PMC1_SPOS1	U7PHY5	U7PMC1	TFIIB-type domain-containing protein.	Uncharacterized protein.	0.996
U7PHY5_SPOS1	U7PML0_SPOS1	U7PHY5	U7PML0	TFIIB-type domain-containing protein.	Uncharacterized protein.	0.978
U7PHY5_SPOS1	U7PPJ0_SPOS1	U7PHY5	U7PPJ0	TFIIB-type domain-containing protein.	Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...]	0.964
U7PHY5_SPOS1	U7PPJ1_SPOS1	U7PHY5	U7PPJ1	TFIIB-type domain-containing protein.	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.	0.967
U7PHY5_SPOS1	U7PRE2_SPOS1	U7PHY5	U7PRE2	TFIIB-type domain-containing protein.	CBFD_NFYB_HMF domain-containing protein.	0.589
U7PHY5_SPOS1	U7PVZ2_SPOS1	U7PHY5	U7PVZ2	TFIIB-type domain-containing protein.	CBFD_NFYB_HMF domain-containing protein.	0.650
U7PHY5_SPOS1	U7PWX9_SPOS1	U7PHY5	U7PWX9	TFIIB-type domain-containing protein.	Uncharacterized protein.	0.897
U7PHY5_SPOS1	U7PYB0_SPOS1	U7PHY5	U7PYB0	TFIIB-type domain-containing protein.	DUF3591 domain-containing protein.	0.982
U7PHY5_SPOS1	U7Q091_SPOS1	U7PHY5	U7Q091	TFIIB-type domain-containing protein.	TAFII28 domain-containing protein.	0.933
U7PHY5_SPOS1	U7Q0H8_SPOS1	U7PHY5	U7Q0H8	TFIIB-type domain-containing protein.	TAF domain-containing protein.	0.926
U7PHY5_SPOS1	U7Q3S9_SPOS1	U7PHY5	U7Q3S9	TFIIB-type domain-containing protein.	Uncharacterized protein.	0.963
U7PHY5_SPOS1	U7Q4Q9_SPOS1	U7PHY5	U7Q4Q9	TFIIB-type domain-containing protein.	Transcription elongation factor S-II.	0.981
U7PHY5_SPOS1	U7Q6Z0_SPOS1	U7PHY5	U7Q6Z0	TFIIB-type domain-containing protein.	Acyl_transf_3 domain-containing protein.	0.933
U7PHY5_SPOS1	U7Q7H5_SPOS1	U7PHY5	U7Q7H5	TFIIB-type domain-containing protein.	TFIID_20kDa domain-containing protein.	0.955
U7PJY3_SPOS1	U7PHY5_SPOS1	U7PJY3	U7PHY5	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	TFIIB-type domain-containing protein.	0.801
U7PJY3_SPOS1	U7PKU7_SPOS1	U7PJY3	U7PKU7	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	TAFII55_N domain-containing protein.	0.655
U7PJY3_SPOS1	U7PMC1_SPOS1	U7PJY3	U7PMC1	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Uncharacterized protein.	0.799
U7PJY3_SPOS1	U7PML0_SPOS1	U7PJY3	U7PML0	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Uncharacterized protein.	0.656