68 items (Sporothrix schenckii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	U7PMC9_SPOS1	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (314 aa)
	U7Q7Y0_SPOS1	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (699 aa)
	U7Q6I6_SPOS1	Uncharacterized protein. (147 aa)
	U7Q6D7_SPOS1	Peptidase_M3 domain-containing protein. (720 aa)
	U7Q699_SPOS1	SH3 domain-containing protein. (1317 aa)
	U7Q5L7_SPOS1	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (195 aa)
	U7Q5J2_SPOS1	Uncharacterized protein. (422 aa)
	U7Q5H8_SPOS1	Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. (386 aa)
	U7Q4R0_SPOS1	Calponin-homology (CH) domain-containing protein. (875 aa)
	U7Q4J9_SPOS1	Uncharacterized protein. (607 aa)
	U7Q403_SPOS1	SAC domain-containing protein. (1381 aa)
	U7Q3U4_SPOS1	Uncharacterized protein. (657 aa)
	U7Q3F2_SPOS1	Uncharacterized protein. (745 aa)
	U7Q3A3_SPOS1	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1577 aa)
	U7Q305_SPOS1	Uncharacterized protein. (1829 aa)
	U7Q2H6_SPOS1	EH domain-containing protein. (860 aa)
	U7Q236_SPOS1	Uncharacterized protein. (487 aa)
	U7Q154_SPOS1	UDENN domain-containing protein. (956 aa)
	U7Q148_SPOS1	EF-hand domain-containing protein; Belongs to the AAA ATPase family. (978 aa)
	U7Q121_SPOS1	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (390 aa)
	U7Q119_SPOS1	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1885 aa)
	U7Q0M5_SPOS1	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2461 aa)
	U7Q0L0_SPOS1	Uncharacterized protein. (1086 aa)
	U7Q0K9_SPOS1	Uncharacterized protein. (566 aa)
	U7Q0C2_SPOS1	Uncharacterized protein. (738 aa)
	U7Q083_SPOS1	Uncharacterized protein. (879 aa)
	U7PZP1_SPOS1	Zn(2)-C6 fungal-type domain-containing protein. (1037 aa)
	U7PZG3_SPOS1	Uncharacterized protein; Belongs to the actin family. (675 aa)
	U7PZF6_SPOS1	Uncharacterized protein. (339 aa)
	U7PZD1_SPOS1	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (291 aa)
	U7PZB9_SPOS1	Uncharacterized protein. (460 aa)
	U7PXT6_SPOS1	Uncharacterized protein. (217 aa)
	U7PXA0_SPOS1	Uncharacterized protein. (373 aa)
	U7PX30_SPOS1	Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (209 aa)
	U7PWY4_SPOS1	C2 domain-containing protein. (1119 aa)
	U7PWT4_SPOS1	TGc domain-containing protein. (821 aa)
	U7PWD2_SPOS1	Uncharacterized protein. (984 aa)
	U7PWC2_SPOS1	Coronin; Belongs to the WD repeat coronin family. (632 aa)
	U7PW93_SPOS1	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (283 aa)
	U7PVY5_SPOS1	NAK/BIKE protein kinase. (1181 aa)
	U7PVU0_SPOS1	Uncharacterized protein. (317 aa)
	U7PVI5_SPOS1	Uncharacterized protein. (239 aa)
	U7PV55_SPOS1	Uncharacterized protein. (1659 aa)
	U7PUL4_SPOS1	Non-specific serine/threonine protein kinase. (882 aa)
	U7PUG2_SPOS1	Uncharacterized protein. (986 aa)
	U7PTP2_SPOS1	AB hydrolase-1 domain-containing protein. (334 aa)
	U7PTM7_SPOS1	Uncharacterized protein. (224 aa)
	U7PTE4_SPOS1	Uncharacterized protein. (1484 aa)
	U7PT61_SPOS1	Uncharacterized protein; Belongs to the AAA ATPase family. (440 aa)
	U7PSK4_SPOS1	Uncharacterized protein. (154 aa)
	U7PSJ5_SPOS1	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family. (365 aa)
	U7PRN9_SPOS1	Uncharacterized protein. (176 aa)
	U7PR71_SPOS1	Uncharacterized protein. (298 aa)
	U7PQ94_SPOS1	Uncharacterized protein. (981 aa)
	U7PQ56_SPOS1	Uncharacterized protein; Belongs to the actin family. (438 aa)
	U7PPQ2_SPOS1	ADF-H domain-containing protein. (153 aa)
	U7PPL6_SPOS1	Uncharacterized protein. (662 aa)
	U7PPG8_SPOS1	Myosin-1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1240 aa)
	U7PML6_SPOS1	Uncharacterized protein. (927 aa)
	U7PMK4_SPOS1	Uncharacterized protein. (443 aa)
	U7PMJ5_SPOS1	Actin cytoskeleton-regulatory complex protein END3. (408 aa)
	U7PM57_SPOS1	WH2 domain-containing protein. (547 aa)
	U7PM32_SPOS1	Uncharacterized protein. (827 aa)
	U7PLU1_SPOS1	Uncharacterized protein. (1426 aa)
	U7PLB6_SPOS1	Actin. (422 aa)
	U7PKA4_SPOS1	Uncharacterized protein. (210 aa)
	U7PJK2_SPOS1	SH3 domain-containing protein. (1346 aa)
	U7PH76_SPOS1	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (568 aa)

Your Current Organism:

Sporothrix schenckii

NCBI taxonomy Id: 1391915
Other names: S. schenckii ATCC 58251, Sporothrix schenckii ATCC 58251

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
U7PJK2_SPOS1	U7PUG2_SPOS1	U7PJK2	U7PUG2	SH3 domain-containing protein.	Uncharacterized protein.	0.407
U7PJK2_SPOS1	U7PV55_SPOS1	U7PJK2	U7PV55	SH3 domain-containing protein.	Uncharacterized protein.	0.533
U7PJK2_SPOS1	U7PWD2_SPOS1	U7PJK2	U7PWD2	SH3 domain-containing protein.	Uncharacterized protein.	0.874
U7PJK2_SPOS1	U7PWY4_SPOS1	U7PJK2	U7PWY4	SH3 domain-containing protein.	C2 domain-containing protein.	0.471
U7PKA4_SPOS1	U7PLB6_SPOS1	U7PKA4	U7PLB6	Uncharacterized protein.	Actin.	0.942
U7PKA4_SPOS1	U7PPL6_SPOS1	U7PKA4	U7PPL6	Uncharacterized protein.	Uncharacterized protein.	0.999
U7PKA4_SPOS1	U7PQ56_SPOS1	U7PKA4	U7PQ56	Uncharacterized protein.	Uncharacterized protein; Belongs to the actin family.	0.810
U7PKA4_SPOS1	U7PVU0_SPOS1	U7PKA4	U7PVU0	Uncharacterized protein.	Uncharacterized protein.	0.839
U7PKA4_SPOS1	U7PW93_SPOS1	U7PKA4	U7PW93	Uncharacterized protein.	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.839
U7PKA4_SPOS1	U7PXT6_SPOS1	U7PKA4	U7PXT6	Uncharacterized protein.	Uncharacterized protein.	0.999
U7PKA4_SPOS1	U7PZD1_SPOS1	U7PKA4	U7PZD1	Uncharacterized protein.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.968
U7PKA4_SPOS1	U7PZG3_SPOS1	U7PKA4	U7PZG3	Uncharacterized protein.	Uncharacterized protein; Belongs to the actin family.	0.977
U7PKA4_SPOS1	U7Q0C2_SPOS1	U7PKA4	U7Q0C2	Uncharacterized protein.	Uncharacterized protein.	0.977
U7PKA4_SPOS1	U7Q121_SPOS1	U7PKA4	U7Q121	Uncharacterized protein.	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	0.800
U7PLB6_SPOS1	U7PKA4_SPOS1	U7PLB6	U7PKA4	Actin.	Uncharacterized protein.	0.942
U7PLB6_SPOS1	U7PLU1_SPOS1	U7PLB6	U7PLU1	Actin.	Uncharacterized protein.	0.515
U7PLB6_SPOS1	U7PM32_SPOS1	U7PLB6	U7PM32	Actin.	Uncharacterized protein.	0.526
U7PLB6_SPOS1	U7PM57_SPOS1	U7PLB6	U7PM57	Actin.	WH2 domain-containing protein.	0.812
U7PLB6_SPOS1	U7PMC9_SPOS1	U7PLB6	U7PMC9	Actin.	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	0.947
U7PLB6_SPOS1	U7PMJ5_SPOS1	U7PLB6	U7PMJ5	Actin.	Actin cytoskeleton-regulatory complex protein END3.	0.656