STRINGSTRING
U7Q4K5_SPOS1 U7Q4K5_SPOS1 U7Q7S0_SPOS1 U7Q7S0_SPOS1 NBP35 NBP35 U7PQA3_SPOS1 U7PQA3_SPOS1 U7PRK0_SPOS1 U7PRK0_SPOS1 U7PRM5_SPOS1 U7PRM5_SPOS1 DRE2 DRE2 U7PW76_SPOS1 U7PW76_SPOS1 U7PWN1_SPOS1 U7PWN1_SPOS1 U7PK18_SPOS1 U7PK18_SPOS1 U7PZ35_SPOS1 U7PZ35_SPOS1 U7PZ63_SPOS1 U7PZ63_SPOS1 CFD1 CFD1 U7Q3P9_SPOS1 U7Q3P9_SPOS1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
U7Q4K5_SPOS1DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (468 aa)
U7Q7S0_SPOS1Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (294 aa)
NBP35Cytosolic Fe-S cluster assembly factor NBP35; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. (353 aa)
U7PQA3_SPOS1DNA polymerase. (1545 aa)
U7PRK0_SPOS1Biotin synthase. (402 aa)
U7PRM5_SPOS1DNA polymerase. (1652 aa)
DRE2Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] (331 aa)
U7PW76_SPOS1DNA polymerase. (1115 aa)
U7PWN1_SPOS1DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2402 aa)
U7PK18_SPOS1NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (525 aa)
U7PZ35_SPOS1Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (444 aa)
U7PZ63_SPOS1Oxidored_q6 domain-containing protein; Belongs to the complex I 20 kDa subunit family. (216 aa)
CFD1Cytosolic Fe-S cluster assembly factor CFD1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily. (306 aa)
U7Q3P9_SPOS1NADH-ubiquinone oxidoreductase 19.3 kDa subunit, mitochondrial; Belongs to the complex I 20 kDa subunit family. (245 aa)
Your Current Organism:
Sporothrix schenckii
NCBI taxonomy Id: 1391915
Other names: S. schenckii ATCC 58251, Sporothrix schenckii ATCC 58251
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