STRINGSTRING
U7PWX5_SPOS1 U7PWX5_SPOS1 U7PX18_SPOS1 U7PX18_SPOS1 U7PX89_SPOS1 U7PX89_SPOS1 U7PXA2_SPOS1 U7PXA2_SPOS1 U7PXC1_SPOS1 U7PXC1_SPOS1 U7PXD2_SPOS1 U7PXD2_SPOS1 U7PXN5_SPOS1 U7PXN5_SPOS1 U7PXY6_SPOS1 U7PXY6_SPOS1 U7PY86_SPOS1 U7PY86_SPOS1 U7PYF3_SPOS1 U7PYF3_SPOS1 U7PYI6_SPOS1 U7PYI6_SPOS1 CLU1 CLU1 U7PYY7_SPOS1 U7PYY7_SPOS1 U7PYZ1_SPOS1 U7PYZ1_SPOS1 TRM8 TRM8 U7Q0P8_SPOS1 U7Q0P8_SPOS1 U7Q0T2_SPOS1 U7Q0T2_SPOS1 U7Q0V7_SPOS1 U7Q0V7_SPOS1 U7Q151_SPOS1 U7Q151_SPOS1 U7Q198_SPOS1 U7Q198_SPOS1 U7Q1F6_SPOS1 U7Q1F6_SPOS1 U7Q1N4_SPOS1 U7Q1N4_SPOS1 U7Q1R1_SPOS1 U7Q1R1_SPOS1 U7Q1R5_SPOS1 U7Q1R5_SPOS1 U7Q1T1_SPOS1 U7Q1T1_SPOS1 U7Q202_SPOS1 U7Q202_SPOS1 TIF32 TIF32 U7Q237_SPOS1 U7Q237_SPOS1 U7Q264_SPOS1 U7Q264_SPOS1 U7Q2I3_SPOS1 U7Q2I3_SPOS1 U7Q2M7_SPOS1 U7Q2M7_SPOS1 U7Q334_SPOS1 U7Q334_SPOS1 U7Q3D2_SPOS1 U7Q3D2_SPOS1 U7Q3I6_SPOS1 U7Q3I6_SPOS1 U7Q3Y8_SPOS1 U7Q3Y8_SPOS1 U7Q456_SPOS1 U7Q456_SPOS1 U7Q4D7_SPOS1 U7Q4D7_SPOS1 LSM5 LSM5 U7Q4F5_SPOS1 U7Q4F5_SPOS1 U7Q4S2_SPOS1 U7Q4S2_SPOS1 U7Q4V0_SPOS1 U7Q4V0_SPOS1 U7Q4Z0_SPOS1 U7Q4Z0_SPOS1 ALA1 ALA1 U7Q570_SPOS1 U7Q570_SPOS1 U7Q5J8_SPOS1 U7Q5J8_SPOS1 U7Q5S4_SPOS1 U7Q5S4_SPOS1 U7Q5W1_SPOS1 U7Q5W1_SPOS1 U7Q632_SPOS1 U7Q632_SPOS1 U7Q6C8_SPOS1 U7Q6C8_SPOS1 U7Q6E1_SPOS1 U7Q6E1_SPOS1 U7Q6K6_SPOS1 U7Q6K6_SPOS1 U7Q6Q9_SPOS1 U7Q6Q9_SPOS1 U7Q6T2_SPOS1 U7Q6T2_SPOS1 U7Q7R0_SPOS1 U7Q7R0_SPOS1 U7Q8D4_SPOS1 U7Q8D4_SPOS1 U7Q825_SPOS1 U7Q825_SPOS1 U7PHD5_SPOS1 U7PHD5_SPOS1 U7PIX4_SPOS1 U7PIX4_SPOS1 LSM1 LSM1 U7PK96_SPOS1 U7PK96_SPOS1 U7PKC8_SPOS1 U7PKC8_SPOS1 U7PKJ8_SPOS1 U7PKJ8_SPOS1 U7PKM0_SPOS1 U7PKM0_SPOS1 U7PKQ3_SPOS1 U7PKQ3_SPOS1 U7PKV1_SPOS1 U7PKV1_SPOS1 PRT1 PRT1 U7PLF3_SPOS1 U7PLF3_SPOS1 U7PLU2_SPOS1 U7PLU2_SPOS1 U7PLY4_SPOS1 U7PLY4_SPOS1 U7PM14_SPOS1 U7PM14_SPOS1 U7PM22_SPOS1 U7PM22_SPOS1 LSM8 LSM8 U7PMB2_SPOS1 U7PMB2_SPOS1 U7PME6_SPOS1 U7PME6_SPOS1 U7PMF8_SPOS1 U7PMF8_SPOS1 U7PMS9_SPOS1 U7PMS9_SPOS1 U7PMZ2_SPOS1 U7PMZ2_SPOS1 U7PN20_SPOS1 U7PN20_SPOS1 U7PN84_SPOS1 U7PN84_SPOS1 U7PNB1_SPOS1 U7PNB1_SPOS1 U7PNB7_SPOS1 U7PNB7_SPOS1 U7Q9L8_SPOS1 U7Q9L8_SPOS1 U7PNK1_SPOS1 U7PNK1_SPOS1 U7PNQ0_SPOS1 U7PNQ0_SPOS1 U7PNU0_SPOS1 U7PNU0_SPOS1 U7PNY4_SPOS1 U7PNY4_SPOS1 LSM4 LSM4 U7PPT4_SPOS1 U7PPT4_SPOS1 U7PQ67_SPOS1 U7PQ67_SPOS1 U7PQA5_SPOS1 U7PQA5_SPOS1 U7PQB0_SPOS1 U7PQB0_SPOS1 U7PQJ1_SPOS1 U7PQJ1_SPOS1 U7PQK3_SPOS1 U7PQK3_SPOS1 U7PQL9_SPOS1 U7PQL9_SPOS1 U7PSI7_SPOS1 U7PSI7_SPOS1 U7PT44_SPOS1 U7PT44_SPOS1 U7PT78_SPOS1 U7PT78_SPOS1 U7PTD0_SPOS1 U7PTD0_SPOS1 U7PTF0_SPOS1 U7PTF0_SPOS1 U7PTF1_SPOS1 U7PTF1_SPOS1 U7PTG0_SPOS1 U7PTG0_SPOS1 U7PTH7_SPOS1 U7PTH7_SPOS1 TIF35 TIF35 U7PTI8_SPOS1 U7PTI8_SPOS1 U7PTK5_SPOS1 U7PTK5_SPOS1 U7PU18_SPOS1 U7PU18_SPOS1 U7PU83_SPOS1 U7PU83_SPOS1 U7PV50_SPOS1 U7PV50_SPOS1 U7PV74_SPOS1 U7PV74_SPOS1 U7PVF4_SPOS1 U7PVF4_SPOS1 LSM3 LSM3 U7PVU9_SPOS1 U7PVU9_SPOS1 NCS6 NCS6 U7PWM3_SPOS1 U7PWM3_SPOS1 U7PWS4_SPOS1 U7PWS4_SPOS1 U7PWU6_SPOS1 U7PWU6_SPOS1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
U7PWX5_SPOS1rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (376 aa)
U7PX18_SPOS1Sm domain-containing protein. (85 aa)
U7PX89_SPOS1Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (756 aa)
U7PXA2_SPOS1Uncharacterized protein. (635 aa)
U7PXC1_SPOS1Matrin-type domain-containing protein. (339 aa)
U7PXD2_SPOS1Uncharacterized protein. (324 aa)
U7PXN5_SPOS1Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (493 aa)
U7PXY6_SPOS1RRM domain-containing protein. (365 aa)
U7PY86_SPOS1Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (96 aa)
U7PYF3_SPOS1Nuclear cap-binding protein subunit 2. (230 aa)
U7PYI6_SPOS1RRM domain-containing protein. (302 aa)
CLU1Clustered mitochondria protein homolog; mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. (1307 aa)
U7PYY7_SPOS1RRM domain-containing protein. (388 aa)
U7PYZ1_SPOS1ATP-dependent RNA helicase DBP10. (1076 aa)
TRM8tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (316 aa)
U7Q0P8_SPOS1Uncharacterized protein. (812 aa)
U7Q0T2_SPOS1Uncharacterized protein; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (612 aa)
U7Q0V7_SPOS1Exportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Belongs to the exportin family. (1071 aa)
U7Q151_SPOS1Uncharacterized protein. (1275 aa)
U7Q198_SPOS140S ribosomal protein S3-B; Belongs to the universal ribosomal protein uS3 family. (359 aa)
U7Q1F6_SPOS1Uncharacterized protein. (637 aa)
U7Q1N4_SPOS1RRM domain-containing protein. (205 aa)
U7Q1R1_SPOS1Uncharacterized protein. (1826 aa)
U7Q1R5_SPOS1Uncharacterized protein. (535 aa)
U7Q1T1_SPOS1RRM domain-containing protein. (196 aa)
U7Q202_SPOS1RRM domain-containing protein. (574 aa)
TIF32Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (1109 aa)
U7Q237_SPOS1HTH La-type RNA-binding domain-containing protein. (1092 aa)
U7Q264_SPOS1Uncharacterized protein. (242 aa)
U7Q2I3_SPOS1Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (422 aa)
U7Q2M7_SPOS1Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (533 aa)
U7Q334_SPOS1KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. (329 aa)
U7Q3D2_SPOS1Uncharacterized protein; Belongs to the DEAD box helicase family. (917 aa)
U7Q3I6_SPOS1U6 snRNA-associated Sm-like protein LSm6. (84 aa)
U7Q3Y8_SPOS15'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins. (1492 aa)
U7Q456_SPOS1RRM domain-containing protein. (639 aa)
U7Q4D7_SPOS1RRM domain-containing protein. (914 aa)
LSM5U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (80 aa)
U7Q4F5_SPOS1Uncharacterized protein. (316 aa)
U7Q4S2_SPOS1RRM domain-containing protein. (433 aa)
U7Q4V0_SPOS1Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (267 aa)
U7Q4Z0_SPOS1Uncharacterized protein. (510 aa)
ALA1Alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family. (960 aa)
U7Q570_SPOS1Uncharacterized protein. (455 aa)
U7Q5J8_SPOS1Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (246 aa)
U7Q5S4_SPOS1tRNA-binding domain-containing protein. (409 aa)
U7Q5W1_SPOS1RNA helicase. (861 aa)
U7Q632_SPOS1Uncharacterized protein. (209 aa)
U7Q6C8_SPOS1Uncharacterized protein. (641 aa)
U7Q6E1_SPOS1N2,N2-dimethylguanosine tRNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (722 aa)
U7Q6K6_SPOS1RNA helicase. (647 aa)
U7Q6Q9_SPOS1U3 small nucleolar RNA-associated protein 22. (1220 aa)
U7Q6T2_SPOS1RRM domain-containing protein. (462 aa)
U7Q7R0_SPOS1THUMP domain-containing protein. (218 aa)
U7Q8D4_SPOS1D-aminoacyl-tRNA deacylase. (164 aa)
U7Q825_SPOS160S ribosome subunit biogenesis protein NIP7; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (188 aa)
U7PHD5_SPOS1RRM domain-containing protein. (172 aa)
U7PIX4_SPOS1Uncharacterized protein. (655 aa)
LSM1U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation. (181 aa)
U7PK96_SPOS1RRM domain-containing protein. (785 aa)
U7PKC8_SPOS1U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (102 aa)
U7PKJ8_SPOS1Ribosomal RNA small subunit methyltransferase B; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (760 aa)
U7PKM0_SPOS1Uncharacterized protein. (839 aa)
U7PKQ3_SPOS1RNA-dependent RNA polymerase. (1301 aa)
U7PKV1_SPOS1RRM domain-containing protein. (481 aa)
PRT1Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family. (752 aa)
U7PLF3_SPOS1Uncharacterized protein. (468 aa)
U7PLU2_SPOS1Uncharacterized protein. (427 aa)
U7PLY4_SPOS1S4 RNA-binding domain-containing protein. (183 aa)
U7PM14_SPOS1Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (276 aa)
U7PM22_SPOS1Uncharacterized protein. (413 aa)
LSM8U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (100 aa)
U7PMB2_SPOS1SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (659 aa)
U7PME6_SPOS1Uncharacterized protein. (621 aa)
U7PMF8_SPOS1Uncharacterized protein. (350 aa)
U7PMS9_SPOS1RRM domain-containing protein. (389 aa)
U7PMZ2_SPOS1RRM domain-containing protein. (350 aa)
U7PN20_SPOS1Uncharacterized protein; Belongs to the helicase family. Dicer subfamily. (1514 aa)
U7PN84_SPOS1Uncharacterized protein. (495 aa)
U7PNB1_SPOS1RRM domain-containing protein. (288 aa)
U7PNB7_SPOS1SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (936 aa)
U7Q9L8_SPOS1RRM domain-containing protein. (580 aa)
U7PNK1_SPOS1RRM domain-containing protein. (264 aa)
U7PNQ0_SPOS1Eukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7- methylguanosine cap of a subset of mRNAs. (584 aa)
U7PNU0_SPOS1RNA helicase. (724 aa)
U7PNY4_SPOS1Uncharacterized protein. (1156 aa)
LSM4U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (159 aa)
U7PPT4_SPOS1Small nuclear ribonucleoprotein G. (86 aa)
U7PQ67_SPOS1RRM domain-containing protein. (581 aa)
U7PQA5_SPOS1Uncharacterized protein; Belongs to the helicase family. Dicer subfamily. (1676 aa)
U7PQB0_SPOS1RRM domain-containing protein. (382 aa)
U7PQJ1_SPOS1RNA-dependent RNA polymerase. (1442 aa)
U7PQK3_SPOS1Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (127 aa)
U7PQL9_SPOS1S4 RNA-binding domain-containing protein. (419 aa)
U7PSI7_SPOS1Uncharacterized protein. (416 aa)
U7PT44_SPOS1Uncharacterized protein. (310 aa)
U7PT78_SPOS1Uncharacterized protein. (416 aa)
U7PTD0_SPOS1Uncharacterized protein. (557 aa)
U7PTF0_SPOS1Cleavage and polyadenylation specificity factor subunit 2. (1059 aa)
U7PTF1_SPOS140S ribosomal protein S9; Belongs to the universal ribosomal protein uS4 family. (190 aa)
U7PTG0_SPOS1H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (192 aa)
U7PTH7_SPOS1Uncharacterized protein. (790 aa)
TIF35Eukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA. (306 aa)
U7PTI8_SPOS1Signal recognition particle subunit SRP68; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP68 family. (659 aa)
U7PTK5_SPOS1RRM domain-containing protein. (334 aa)
U7PU18_SPOS1RRM domain-containing protein. (109 aa)
U7PU83_SPOS1RRM domain-containing protein. (431 aa)
U7PV50_SPOS1RRM domain-containing protein. (207 aa)
U7PV74_SPOS140S ribosomal protein S4; Belongs to the eukaryotic ribosomal protein eS4 family. (259 aa)
U7PVF4_SPOS1Uncharacterized protein. (404 aa)
LSM3U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (92 aa)
U7PVU9_SPOS1Uncharacterized protein. (945 aa)
NCS6Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. (445 aa)
U7PWM3_SPOS1Uncharacterized protein. (712 aa)
U7PWS4_SPOS1RRM domain-containing protein. (351 aa)
U7PWU6_SPOS1RRM domain-containing protein. (210 aa)
Your Current Organism:
Sporothrix schenckii
NCBI taxonomy Id: 1391915
Other names: S. schenckii ATCC 58251, Sporothrix schenckii ATCC 58251
Server load: medium (52%) [HD]
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