12 items (Sporothrix schenckii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	U7PM29_SPOS1	Uncharacterized protein. (554 aa)
	U7PND5_SPOS1	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family. (504 aa)
	U7PSU0_SPOS1	Uncharacterized protein. (1719 aa)
	U7PW08_SPOS1	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1721 aa)
	U7PXX9_SPOS1	Uncharacterized protein. (705 aa)
	U7PZU4_SPOS1	Ubiquitin-like domain-containing protein. (107 aa)
	U7PZZ8_SPOS1	Uncharacterized protein. (477 aa)
	U7Q5E2_SPOS1	Vezatin domain-containing protein. (694 aa)
	U7Q6Z7_SPOS1	SUMO-conjugating enzyme ubc9; Belongs to the ubiquitin-conjugating enzyme family. (157 aa)
	U7Q781_SPOS1	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (259 aa)
	U7Q7S5_SPOS1	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (894 aa)
	U7Q9G4_SPOS1	Uncharacterized protein. (230 aa)

Your Current Organism:

Sporothrix schenckii

NCBI taxonomy Id: 1391915
Other names: S. schenckii ATCC 58251, Sporothrix schenckii ATCC 58251

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
U7PM29_SPOS1	U7PZU4_SPOS1	U7PM29	U7PZU4	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.850
U7PM29_SPOS1	U7Q5E2_SPOS1	U7PM29	U7Q5E2	Uncharacterized protein.	Vezatin domain-containing protein.	0.643
U7PM29_SPOS1	U7Q6Z7_SPOS1	U7PM29	U7Q6Z7	Uncharacterized protein.	SUMO-conjugating enzyme ubc9; Belongs to the ubiquitin-conjugating enzyme family.	0.789
U7PM29_SPOS1	U7Q781_SPOS1	U7PM29	U7Q781	Uncharacterized protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.643
U7PM29_SPOS1	U7Q7S5_SPOS1	U7PM29	U7Q7S5	Uncharacterized protein.	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]	0.920
U7PND5_SPOS1	U7PSU0_SPOS1	U7PND5	U7PSU0	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family.	Uncharacterized protein.	0.987
U7PND5_SPOS1	U7PXX9_SPOS1	U7PND5	U7PXX9	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family.	Uncharacterized protein.	0.800
U7PND5_SPOS1	U7PZU4_SPOS1	U7PND5	U7PZU4	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family.	Ubiquitin-like domain-containing protein.	0.740
U7PND5_SPOS1	U7PZZ8_SPOS1	U7PND5	U7PZZ8	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family.	Uncharacterized protein.	0.999
U7PND5_SPOS1	U7Q6Z7_SPOS1	U7PND5	U7Q6Z7	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family.	SUMO-conjugating enzyme ubc9; Belongs to the ubiquitin-conjugating enzyme family.	0.729
U7PND5_SPOS1	U7Q9G4_SPOS1	U7PND5	U7Q9G4	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family.	Uncharacterized protein.	0.800
U7PSU0_SPOS1	U7PND5_SPOS1	U7PSU0	U7PND5	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family.	0.987
U7PSU0_SPOS1	U7PXX9_SPOS1	U7PSU0	U7PXX9	Uncharacterized protein.	Uncharacterized protein.	0.786
U7PSU0_SPOS1	U7PZU4_SPOS1	U7PSU0	U7PZU4	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.673
U7PSU0_SPOS1	U7PZZ8_SPOS1	U7PSU0	U7PZZ8	Uncharacterized protein.	Uncharacterized protein.	0.999
U7PSU0_SPOS1	U7Q6Z7_SPOS1	U7PSU0	U7Q6Z7	Uncharacterized protein.	SUMO-conjugating enzyme ubc9; Belongs to the ubiquitin-conjugating enzyme family.	0.743
U7PSU0_SPOS1	U7Q9G4_SPOS1	U7PSU0	U7Q9G4	Uncharacterized protein.	Uncharacterized protein.	0.786
U7PW08_SPOS1	U7PZU4_SPOS1	U7PW08	U7PZU4	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	Ubiquitin-like domain-containing protein.	0.872
U7PW08_SPOS1	U7Q5E2_SPOS1	U7PW08	U7Q5E2	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	Vezatin domain-containing protein.	0.645
U7PW08_SPOS1	U7Q6Z7_SPOS1	U7PW08	U7Q6Z7	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	SUMO-conjugating enzyme ubc9; Belongs to the ubiquitin-conjugating enzyme family.	0.856