22 items (Aspergillus novofumigatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A2I1CDF1	Polyketide_cyc domain-containing protein. (239 aa)
	A0A2I1BU98	Uncharacterized protein. (362 aa)
	A0A2I1BUL7	Uncharacterized protein. (357 aa)
	A0A2I1BYN9	Putative UDP-galactose 4-epimerase. (344 aa)
	COQ4	Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family. (285 aa)
	COQ6	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (510 aa)
	COQ3	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (342 aa)
	A0A2I1C5B0	NAD(P)-binding protein. (287 aa)
	A0A2I1C6F9	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. (414 aa)
	A0A2I1CBM3	NAD(P)-binding protein. (696 aa)
	A0A2I1CBR8	S-adenosyl-L-methionine-dependent methyltransferase. (241 aa)
	A0A2I1CBS5	Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. (297 aa)
	A0A2I1CBY2	Uncharacterized protein. (266 aa)
	COQ5	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (313 aa)
	A0A2I1CN57	NADPH:adrenodoxin oxidoreductase, mitochondrial. (537 aa)
	A0A2I1CNS8	Putative methyltransferase. (239 aa)
	A0A2I1CPI3	Uncharacterized protein. (405 aa)
	A0A2I1CE19	Putative molecular chaperone. (738 aa)
	A0A2I1CGC0	2Fe-2S iron-sulfur cluster binding domain protein. (200 aa)
	A0A2I1CHB7	Putative ubiE/COQ5 methyltransferase. (264 aa)
	A0A2I1CI34	F-box domain protein. (447 aa)
	COQ7	5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. (257 aa)

Your Current Organism:

Aspergillus novofumigatus

NCBI taxonomy Id: 1392255
Other names: A. novofumigatus IBT 16806, Aspergillus novofumigatus IBT 16806

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A2I1BU98	A0A2I1C5B0	A0A2I1BU98	A0A2I1C5B0	Uncharacterized protein.	NAD(P)-binding protein.	0.403
A0A2I1BU98	A0A2I1CBR8	A0A2I1BU98	A0A2I1CBR8	Uncharacterized protein.	S-adenosyl-L-methionine-dependent methyltransferase.	0.458
A0A2I1BU98	A0A2I1CE19	A0A2I1BU98	A0A2I1CE19	Uncharacterized protein.	Putative molecular chaperone.	0.688
A0A2I1BU98	A0A2I1CHB7	A0A2I1BU98	A0A2I1CHB7	Uncharacterized protein.	Putative ubiE/COQ5 methyltransferase.	0.580
A0A2I1BU98	A0A2I1CI34	A0A2I1BU98	A0A2I1CI34	Uncharacterized protein.	F-box domain protein.	0.458
A0A2I1BU98	A0A2I1CNS8	A0A2I1BU98	A0A2I1CNS8	Uncharacterized protein.	Putative methyltransferase.	0.458
A0A2I1BU98	A0A2I1CPI3	A0A2I1BU98	A0A2I1CPI3	Uncharacterized protein.	Uncharacterized protein.	0.458
A0A2I1BU98	COQ3	A0A2I1BU98	A0A2I1C514	Uncharacterized protein.	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	0.590
A0A2I1BU98	COQ4	A0A2I1BU98	A0A2I1C1Z1	Uncharacterized protein.	Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family.	0.583
A0A2I1BU98	COQ5	A0A2I1BU98	A0A2I1CCY3	Uncharacterized protein.	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2).	0.638
A0A2I1BU98	COQ6	A0A2I1BU98	A0A2I1C4F8	Uncharacterized protein.	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.	0.608
A0A2I1BU98	COQ7	A0A2I1BU98	A0A2I1CKF6	Uncharacterized protein.	5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides.	0.843
A0A2I1BUL7	A0A2I1C5B0	A0A2I1BUL7	A0A2I1C5B0	Uncharacterized protein.	NAD(P)-binding protein.	0.403
A0A2I1BUL7	A0A2I1CBR8	A0A2I1BUL7	A0A2I1CBR8	Uncharacterized protein.	S-adenosyl-L-methionine-dependent methyltransferase.	0.458
A0A2I1BUL7	A0A2I1CE19	A0A2I1BUL7	A0A2I1CE19	Uncharacterized protein.	Putative molecular chaperone.	0.688
A0A2I1BUL7	A0A2I1CHB7	A0A2I1BUL7	A0A2I1CHB7	Uncharacterized protein.	Putative ubiE/COQ5 methyltransferase.	0.580
A0A2I1BUL7	A0A2I1CI34	A0A2I1BUL7	A0A2I1CI34	Uncharacterized protein.	F-box domain protein.	0.458
A0A2I1BUL7	A0A2I1CNS8	A0A2I1BUL7	A0A2I1CNS8	Uncharacterized protein.	Putative methyltransferase.	0.458
A0A2I1BUL7	A0A2I1CPI3	A0A2I1BUL7	A0A2I1CPI3	Uncharacterized protein.	Uncharacterized protein.	0.458
A0A2I1BUL7	COQ3	A0A2I1BUL7	A0A2I1C514	Uncharacterized protein.	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	0.590