(29 nodes) Cellular response to topologically incorrect protein network (Aspergillus novofumigatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A2I1C621	DUF1977-domain-containing protein. (349 aa)
	A0A2I1CDW4	Putative Hsp70 nucleotide exchange factor. (216 aa)
	A0A2I1CGL5	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (263 aa)
	A0A2I1CHH6	Putative C2H2 finger and ankyrin domain protein. (616 aa)
	A0A2I1CHW4	Bax inhibitor family protein; Belongs to the BI1 family. (249 aa)
	A0A2I1CHW5	Putative clock controled protein (Ccg-8). (576 aa)
	A0A2I1CJU1	LysM domain-containing protein. (205 aa)
	A0A2I1C7X7	Ubiquitin-like domain-containing protein. (605 aa)
	A0A2I1C811	Ubiquitin carboxyl-terminal hydrolase. (291 aa)
	A0A2I1C841	Putative heat shock protein Hsp98/Hsp104/ClpA; Belongs to the ClpA/ClpB family. (927 aa)
	A0A2I1C9P9	Uncharacterized protein. (707 aa)
	A0A2I1CA82	Heat shock protein 70; Belongs to the heat shock protein 70 family. (629 aa)
	A0A2I1CAH1	Golgi phospho protein 3 domain-containing protein. (353 aa)
	A0A2I1CAP6	BAG domain protein. (391 aa)
	A0A2I1CMR8	U-box domain protein. (307 aa)
	A0A2I1CPQ0	Cell division control protein Cdc48; Belongs to the AAA ATPase family. (819 aa)
	A0A2I1CMF3	Heat shock protein 70; Belongs to the heat shock protein 70 family. (662 aa)
	A0A2I1BWF0	Putative endoplasmic reticulum and nuclear membrane proteinc Npl4. (603 aa)
	A0A2I1BWI4	Putative ubiquitin fusion degradation protein Ufd1. (369 aa)
	A0A2I1CM99	Putative antigenic mitochondrial protein HSP60; Belongs to the chaperonin (HSP60) family. (588 aa)
	A0A2I1BWR7	Protein kinase domain-containing protein. (224 aa)
	A0A2I1BWY5	Uncharacterized protein. (1147 aa)
	A0A2I1C017	Putative misfolded glyco proteins degradation protein Yos9. (510 aa)
	A0A2I1C1S3	Putative OTU-like cysteine protease. (338 aa)
	A0A2I1CKB6	Putative sulfate transporter. (437 aa)
	A0A2I1CKJ7	Putative UDP-glucose:glyco protein glucosyltransferase. (1487 aa)
	A0A2I1CL83	Putative ER Hsp70 chaperone BiP; Belongs to the heat shock protein 70 family. (672 aa)
	A0A2I1C612	Tethering factor for nuclear proteasome sts1; Involved in ubiquitin-mediated protein degradation. Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates. Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins. (313 aa)
	A0A2I1C616	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (465 aa)

Your Current Organism:

Aspergillus novofumigatus

NCBI taxonomy Id: 1392255
Other names: A. novofumigatus IBT 16806, Aspergillus novofumigatus IBT 16806

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A2I1BWF0	A0A2I1BWI4	Putative endoplasmic reticulum and nuclear membrane proteinc Npl4.	Putative ubiquitin fusion degradation protein Ufd1.	0.998
A0A2I1BWF0	A0A2I1C017	Putative endoplasmic reticulum and nuclear membrane proteinc Npl4.	Putative misfolded glyco proteins degradation protein Yos9.	0.867
A0A2I1BWF0	A0A2I1C1S3	Putative endoplasmic reticulum and nuclear membrane proteinc Npl4.	Putative OTU-like cysteine protease.	0.968
A0A2I1BWF0	A0A2I1CGL5	Putative endoplasmic reticulum and nuclear membrane proteinc Npl4.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.967
A0A2I1BWF0	A0A2I1CHH6	Putative endoplasmic reticulum and nuclear membrane proteinc Npl4.	Putative C2H2 finger and ankyrin domain protein.	0.542
A0A2I1BWF0	A0A2I1CPQ0	Putative endoplasmic reticulum and nuclear membrane proteinc Npl4.	Cell division control protein Cdc48; Belongs to the AAA ATPase family.	0.998
A0A2I1BWI4	A0A2I1BWF0	Putative ubiquitin fusion degradation protein Ufd1.	Putative endoplasmic reticulum and nuclear membrane proteinc Npl4.	0.998
A0A2I1BWI4	A0A2I1C017	Putative ubiquitin fusion degradation protein Ufd1.	Putative misfolded glyco proteins degradation protein Yos9.	0.501
A0A2I1BWI4	A0A2I1C1S3	Putative ubiquitin fusion degradation protein Ufd1.	Putative OTU-like cysteine protease.	0.972
A0A2I1BWI4	A0A2I1CGL5	Putative ubiquitin fusion degradation protein Ufd1.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.972
A0A2I1BWI4	A0A2I1CHH6	Putative ubiquitin fusion degradation protein Ufd1.	Putative C2H2 finger and ankyrin domain protein.	0.503
A0A2I1BWI4	A0A2I1CPQ0	Putative ubiquitin fusion degradation protein Ufd1.	Cell division control protein Cdc48; Belongs to the AAA ATPase family.	0.995
A0A2I1BWR7	A0A2I1C017	Protein kinase domain-containing protein.	Putative misfolded glyco proteins degradation protein Yos9.	0.486
A0A2I1BWR7	A0A2I1CL83	Protein kinase domain-containing protein.	Putative ER Hsp70 chaperone BiP; Belongs to the heat shock protein 70 family.	0.969
A0A2I1BWR7	A0A2I1CMR8	Protein kinase domain-containing protein.	U-box domain protein.	0.617
A0A2I1BWR7	A0A2I1CPQ0	Protein kinase domain-containing protein.	Cell division control protein Cdc48; Belongs to the AAA ATPase family.	0.401
A0A2I1BWY5	A0A2I1C017	Uncharacterized protein.	Putative misfolded glyco proteins degradation protein Yos9.	0.501
A0A2I1BWY5	A0A2I1CL83	Uncharacterized protein.	Putative ER Hsp70 chaperone BiP; Belongs to the heat shock protein 70 family.	0.987
A0A2I1BWY5	A0A2I1CMR8	Uncharacterized protein.	U-box domain protein.	0.618
A0A2I1BWY5	A0A2I1CPQ0	Uncharacterized protein.	Cell division control protein Cdc48; Belongs to the AAA ATPase family.	0.401